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Cited by 40Cardiovascular Health and Disease PreventionCardiac Health and Mental HealthCardiovascular Health and Risk Factors

Childhood Hyperactivity as a Predictor of Carotid Artery Intima Media Thickness Over a Period of 21 Years: The Cardiovascular Risk in Young Finns Study

Keltikangas-Järvinen, Liisa, Pulkki-Råback, Laura, Puttonen, Sampsa, Viikari, Jorma, Raitakari, Olli T.·2006·Psychosomatic Medicine
DOI 10.1097/01.psy.0000227752.24292.3e
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Abstract

OBJECTIVE: We investigated whether childhood temperament was able to predict carotid artery intima media thickness (IMT) and/or its risk factors in adulthood 21 years later. METHODS: The subjects were the three youngest age cohorts of the population-based sample of the Cardiovascular Risk in Young Finns study, i.e., those who were aged 3 to 9 years (n = 708) at the baseline. IMT was assessed by ultrasound, and temperament in terms of negative emotionality, hyperactivity, and sociability (following Buss and Plomin). In addition, the levels of traditional risk factors for atherosclerosis were measured in both childhood and adulthood. RESULTS: Childhood temperament was found to predict adulthood risk factors such as smoking in both genders and body mass index (BMI), systolic blood pressure (SBP), and educational level in women. In women, childhood hyperactivity predicted adulthood IMT after adjustment for childhood and adulthood risk factors for atherosclerosis. CONCLUSION: These findings suggest that temperament may contribute to the development of IMT in two ways: indirectly through risk factors in both genders and in women directly through a mechanism that is not considered in the present study. There were no significant gender-related differences in temperament, but it seemed to play different roles in different genders. Hyperactivity was a greater risk for girls than for boys.

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  • It is not known whether children with ADHD have a coexisting increased incidence of hypertension, although there is evidence of a link.

    “It is not known whether children with ADHD have a coexisting increased incidence of hypertension, although there is evidence of a link [66].”

    From European guidelines on managing adverse effects of medication for ADHD (2011) · cites this paper as [66]

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Authors
Keltikangas-Järvinen, L., Pulkki-Råback, L., Puttonen, S., Viikari, J., & Raitakari, O. T.
Affiliations
University of Helsinki (FI)
ORCID
Venue
Psychosomatic Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2006-07
Volume
68
Issue
4
Pages
509-516
ISSN
0033-3174 (ISSN-L)
DOI
10.1097/01.psy.0000227752.24292.3e
OpenAlex
W2059842747
Cited by
40
References
49
Citations by year
2023: 1 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 1 · 2017: 2 · 2016: 4 · 2015: 1 · 2014: 3 · 2013: 6 · 2012: 2
FWCI
2.13
Type
journal article
Language
en
Open access
closed
Locations
  • Psychosomatic Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
hyperactive children, temperament, carotid intima-media thickness, atherosclerosis, cardiovascular risk factors, smoking, body mass index, systolic blood pressure, educational attainment, sex differences, long-term forecasting, Cardiovascular Risk in Young Finns Study
MeSH terms
Adolescent, Adult, Age Factors, Attention Deficit Disorder with Hyperactivity, Carotid Artery Diseases, Child, Educational Status, Female, Finland, Humans, Longitudinal Studies, Male, Prognosis, Risk Factors, Sex Factors, Smoking, Temperament, Cohort Studies, Comorbidity, Body Mass Index, Prevalence, Carotid Stenosis, Tunica Intima, Tunica Media

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