OneFlorida Clinical Research Consortium: linking a clinical and translational science institute with a community-based distributive medical education model
Open accessAbstract
Problem: Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities—the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami—created (2010–2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings. Approach: OneFlorida has four programs, which report to a steering committee with membership from each partner, community members, and the state Medicaid agency and Department of Health to ensure shared governance. The Clinical Research Program provides support to conduct research in the network and uses champions to engage community clinicians. The Citizen Scientist Program has community members who provide input on health topics of importance to them, study design, recruitment and retention strategies, and the interpretation of findings. The Data Trust Program contains electronic health record and health care claims data for 10.6 million Floridians. The Minority Education Program, in collaboration with three historically black colleges and universities, offers minority junior faculty mentoring in pragmatic clinical trials and implementation science. Outcomes: OneFlorida has implemented 27 studies with diverse patient populations and in diverse community practice settings. Next Steps: To identify evidence-based best practices from the clinical trials conducted in the network, foster their implementation, and expand research training opportunities.
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The OneFlorida Clinical Research Consortium aggregates and harmonizes clinical data from 12 healthcare organizations caring for nearly 15 million Floridians in 22 hospitals and 914 clinical practices across all 67 Florida counties.
“The OneFlorida Clinical Research Consortium is one of nine clinical data research networks funded by PCORI and aggregates, which harmonizes clinical data from 12 healthcare organizations that care for nearly 15 million Floridians in 22 hospitals and 914 clinical practices across all 67 counties of the state of Florida.”
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- Authors
- Shenkman, E., Hurt, M., Hogan, W., Carrasquillo, O., Smith, S., Brickman, A., & Nelson, D.
- Affiliations
- University of Florida Health (US)
- Florida State University (US)
- University of Miami (US)
- is chief scientific officer, Florida Hospital, Orlando, Florida.
- Health Choice Network (US)
- Corresponding author
- Shenkman, Elizabeth
- Venue
- Academic Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-03
- Volume
- 93
- Issue
- 3
- Pages
- 451-455
- ISSN
- 1040-2446 (ISSN-L)
- PMC
- PMC5839715
- OpenAlex
- W2765619636
- Cited by
- 97
- References
- 6
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 9 · 2023: 14 · 2022: 22 · 2021: 16 · 2020: 10 · 2019: 4 · 2018: 5
- FWCI
- 4.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Academic Medicine (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (UL1TR001427, 1ot2od025285-01, UL1TR002736)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Innovations in Medical Education
- Keywords
- pragmatic trials, research consortium, health insurance claims, historically Black colleges and universities, implementation science, research training, shared governance, community participation
- MeSH terms
- Academies and Institutes, Intersectoral Collaboration, Clinical Competence, Education, Medical, Florida, Humans, Practice Guidelines as Topic, Translational Research, Biomedical, Pragmatic Clinical Trials as Topic
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