Cited by 112Myofascial pain diagnosis and treatmentTemporomandibular Joint DisordersPain Mechanisms and Treatments

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Does Mobilization of the Upper Cervical Spine Affect Pain Sensitivity and Autonomic Nervous System Function in Patients With Cervico-craniofacial Pain?: A Randomized-controlled Trial

La Touche, Roy, París-Alemany, Alba, Mannheimer, Jeffrey S., Angulo-Díaz-Parreño, Santiago, Bishop, Mark D., Lopéz-Valverde-Centeno, Antonio, von Piekartz, Harry, Fernández-Carnero, Josue·2013·The Clinical Journal of Pain

DOI 10.1097/ajp.0b013e318250f3cd

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Abstract

Objectives The aims were to investigate the effects of anterior-posterior upper cervical mobilization (APUCM) on pain modulation in craniofacial and cervical regions and its influence on the sympathetic nervous system. Methods Thirty-two patients with cervico-craniofacial pain of myofascial origin were randomly allocated into experimental or placebo groups. Each patient received 3 treatments. Outcome measures included bilateral pressure pain thresholds assessed at craniofacial and cervical points preintervention, after the second intervention and after the final treatment. Pain intensity and sympathetic nervous system variables (skin conductance, breathing rate, heart rate, and skin temperature) were assessed before and immediately after each intervention. Results The pressure pain thresholds in the craniofacial and cervical regions significantly increased (P Discussion This study provided preliminary evidence of a short-term hypoalgesic effect of APUCM on craniofacial and cervical regions of patients with cervico-craniofacial pain of myofascial origin, suggesting that APUCM may cause an immediate nociceptive modulation in the trigeminocervical complex. We also observed a sympathoexcitatory response, which could be related to the hypoalgesic effect induced by the technique, but this aspect should be confirmed in future studies.

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Untitled work
(1992) · PubMed · Cited by 3,804
The Neck Disability Index: a study of reliability and validity.
Vernon, H. T., & Mior, S. A. (1991) · PubMed · Cited by 3,048
Myofascial pain and dysfunction : the trigger point manual
Travell, J. G., & Simons, D. G. (1982) · Medical Entomology and Zoology · Cited by 2,735
Reliability of the Visual Analog Scale for Measurement of Acute Pain
Bijur, P. E., Silver, W. G., & Gallagher, E. J. (2001) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2001.tb01132.x · Cited by 2,091
Clinical Significance of Reported Changes in Pain Severity☆☆☆★
Todd, K. H., Funk, K. G., Funk, J. P., & Bonacci, R. P. (1996) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(96)70238-x · Cited by 1,110
Acute and Chronic Craniofacial Pain: Brainstem Mechanisms of Nociceptive Transmission and Neuroplasticity, and Their Clinical Correlates
Sessle, B. J. (2000) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411000110010401 · Cited by 702
Interrater Reliability of Algometry in Measuring Pressure Pain Thresholds in Healthy Humans, Using Multiple Raters
Chesterton, L. S., Sim, J., Wright, C. C., & Foster, N. E. (2007) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318154b6ae · Cited by 690
Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input
Bartsch, T. (2002) · Brain · doi:10.1093/brain/awf166 · Cited by 475
Cervical mobilisation: concurrent effects on pain, sympathetic nervous system activity and motor activity
Sterling, M. M., Jull, G. A., & Wright, A. (2001) · Manual Therapy · doi:10.1054/math.2000.0378 · Cited by 431
Central distribution of trigeminal and upper cervical primary afferents in the rat studied by anterograde transport of horseradish peroxidase conjugated to wheat germ agglutinin
Pfaller, K., & Arvidsson, J. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902680110 · Cited by 423

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Hammerle, M. H., Lu, L. H., Thomas, L. C., Swan, A. A., Hoppes, C. W., Nelson, J. T., & Treleaven, J. M. (2022) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2022.2085850 · Cited by 10
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Jupin, C., Aibar, V. B., & Sarhan, F. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14113830 · Cited by 9
Autonomic nervous system and endocrine system response to upper and lower cervical spine mobilization in healthy male adults: a randomized crossover trial
Farrell, G., Reily-Bell, M., Chapple, C., Kennedy, E., Sampath, K. K., Gisselman, A. S., Cook, C. E., Katare, R., & Tumilty, S. (2023) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2023.2177071 · Cited by 9
Comparative analysis of the autonomic nervous system response during movement representation in healthy individuals and patients with chronic low back pain: a prospective cohort study
Díaz-Sáez, M. C., Touche, R. L., & Cuenca‐Martínez, F. (2020) · Somatosensory & Motor Research · doi:10.1080/08990220.2020.1845137 · Cited by 9
Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A ‘trustworthy’ systematic review and meta-analysis
Riley, S. P., Swanson, B. T., Shaffer, S. M., Flowers, D. W., Hofbauer, M. A., & Liebano, R. E. (2023) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2023.2247235 · Cited by 8
Effect of high voltage electrical stimulation in temporomandibular disorders: a randomized controlled trial
Arıkan, H., Çıtaker, S., Üçok, C., & Üçok, Ö. (2024) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2024.2321215 · Cited by 7
Restoration of normal central pain processing following manual therapy in nonspecific chronic neck pain
Mata, J. Z., Azkue, J. J., Bialosky, J. E., Sáez, M., López, E. D., Araolaza-Arrieta, M., & Lascurain‐Aguirrebeña, I. (2024) · PLoS ONE · doi:10.1371/journal.pone.0294100 · Cited by 8
Facial Pain and Temporomandibular Joint Dysfunction Secondary to Acromegaly: Treatment With Manual Therapy, Neuromuscular Reeducation—A Case Report
Wechsler, S. (2019) · Rehabilitation Oncology · doi:10.1097/01.reo.0000000000000190 · Cited by 7
Are there differences between a real C0-C1 mobilization and a sham technique in function and pressure pain threshold in patients with chronic neck pain and upper cervical restriction? A randomised controlled clinical trial
Arias-Álvarez, G., Muñoz-Bustos, M., Hidalgo-García, C., Córdova-León, K., Pérez‐Bellmunt, A., López-de–Celis, C., & Rodríguez‐Sanz, J. (2022) · Journal of Back and Musculoskeletal Rehabilitation · doi:10.3233/bmr-220008 · Cited by 7
Graded exposure and orthopedic manual physical therapy for kinesiophobia and function in chronic temporomandibular dysfunction: A case report
Blanchard, L., Goostree, S., & Duncombe, A. (2020) · CRANIO® · doi:10.1080/08869634.2020.1779483 · Cited by 6
Orofacial pain of cervical origin: A case report
Ganesh, G. S., Sahu, M. M., & Tigga, P. (2017) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2017.07.001 · Cited by 6
Autonomic nervous system and viscera-related responses to manual therapy: A narrative overview
Alanazi, M. S., Degenhardt, B. F., Kelley-Franklin, G., Jacobson, E., Fritz, S., Kettner, N. W., Křemen, V., Lipke, L., & Reed, W. R. (2024) · International journal of osteopathic medicine · doi:10.1016/j.ijosm.2024.100735 · Cited by 5
EFFECTS OF BOWEN THERAPY IN PATIENTS WITH TENSION-TYPE HEADACHE: A RANDOMIZED CONTROLLED TRIAL
Qamar, M. M., Basharat, A., Kiran, Q., & Fatima, M. (2023) · Pakistan Journal of Rehabilitation · doi:10.36283/pjr.zu.12.1/005 · Cited by 5
Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of randomised controlled trials
Gordon, T. C., Hope-Bell, J., Draper‐Rodi, J., MacMillan, A., Miller, D., & Edwards, D. J. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-095933 · Cited by 7
Chiropractic care for hypertension: Review of the literature and study of biological and genetic bases.
Sullivan, S. G., Paolacci, S., Kiani, A. K., & Bertelli, M. (2020) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v91i13-s.10524 · Cited by 5
Impact of Indoor Air Quality and Breathing on Back and Neck Pain: A Systematic Review
Gherscovici, E., & Mayer, J. M. (2023) · Cureus · doi:10.7759/cureus.43945 · Cited by 4
Endogenous Neurostimulation and Physiotherapy in Cluster Headache: A Clinical Case
Navarro-Fernández, G., de-la-Puente-Ranea, L., Gandía-González, M. L., & Gil‐Martínez, A. (2019) · Brain Sciences · doi:10.3390/brainsci9030060 · Cited by 4
Temporomandibular Disorders
Armijo-Olivo, S. L., & Gadotti, I. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-31072-7.00004-x · Cited by 4
The addition of thoracic mobilization to aerobic exercise did not alter autonomic function and pain pressure threshold acutely in asymptomatic young people: A randomized controlled trial
Pessoa, M. D. V., de Araujo, F. X., Schell, M. S., da Silva, M. F., & Macagnan, F. E. (2021) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2021.04.008 · Cited by 3
Short-Term Effects of Different Rates of Thoracic Mobilization on Pressure Pain Thresholds in Asymptomatic Individuals: A Randomized Crossover Trial
Araujo, F. X., Schell, M. S., Ferreira, G. E., Pessoa, M. D. V., do Pinho, A. S., Plentz, R. D. M., & da Silva, M. F. (2019) · Journal of Chiropractic Medicine · doi:10.1016/j.jcm.2018.10.002 · Cited by 3
Manuelle Therapietechniken an der Wirbelsäule zur Stimulation des autonomen Nervensystems - ein Scoping Review
Rogan, S., Taeymans, J., Berger, I., & Baur, H. (2023) · Sportverletzung · Sportschaden · doi:10.1055/a-1958-2730 · Cited by 2
Manual therapy and exercise for patients with cluster headache
de-la-Puente-Ranea, L., Gil‐Martínez, A., Rodríguez-López, Ó., González-Gutiérrez, P., Mangas-Guijarro, M. Á., & Navarro-Fernández, G. (2021) · EXCLI journal · doi:10.17179/excli2021-3763 · Cited by 2
Temporomandibular disorders and benefits of a cervical therapeutic approach in facial myalgia treatment: A review of the literature
Aguila, M., Benichou, M., Hennequin, A., Grégoire, G., & Destruhaut, F. (2019) · Oral Health and Care · doi:10.15761/ohc.1000174 · Cited by 2
Larger amplitude spinal mobilization is more effective to decrease pain systematically: A clinical trial using pressure pain thresholds in chronic low back pain participants
Khanmohammadi, M., Rostami, M., Salesi, M., Khazaeipour, Z., Shadmehr, A., Moghadam, B. A., Shirvani, H., Shamsoddini, A., Ghanjal, A., & Sobhani, V. (2020) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2020.11.015 · Cited by 2
Manual therapy and exercise targeted to the neck and orofacial regions for patients with orofacial pain: a systematic review and meta-analysis
Pelai, E. B., de Castro‐Carletti, E. M., Tavares, L. F., Michelotti, A., Pitance, L., Rodrigues-Bigaton, D., Mescollotto, F. F., Dennett, L., & Armijo-Olivo, S. L. (2025) · Disability and Rehabilitation · doi:10.1080/09638288.2025.2539469 · Cited by 1
The Effect of Upper Cervical Manipulation on Autonomic Nervous System in Young Healthy Individuals
Lee, S., & Lee, Y. (2021) · Physical therapy rehabilitation science · doi:10.14474/ptrs.2021.10.2.134 · Cited by 1
The Immediate Hypoalgesic Effect of Low and High Force Thoracic Mobilizations in Asymptomatic Subjects as Measured by Pain Pressure Thresholds (PPT)
Syrgiamiotis, C., Krekoukias, G., Gkouzioti, K., & Hebron, C. (2023) · Diagnostics · doi:10.3390/diagnostics13030544 · Cited by 1
Cervical Spine Range of Motion and Sleep Disturbances in Patients With Atopic Dermatitis: A Cross-Sectional Study
Hosono, S., Fujita, K., Nimura, A., Ibara, T., & Akita, K. (2024) · Cureus · doi:10.7759/cureus.75449 · Cited by 1
Narrative Review: Effects of manipulation and mobilization techniques of cervical spine on pressure pain threshold in neck and shoulder muscles
Zamani, S., Okhovatian, F., & Naimi, S. S. (2016) · Journal of Clinical Physiotherapy Research · doi:10.22037/jcpr.v1i1.10385 · Cited by 1
Tratamiento de fisioterapia multimodal basado en un paradigma bioconductual en el abordaje de migraña crónica: Estudio de un caso.
Suso‐Martí, L., Atger, S., & Cuenca‐Martínez, F. (2019) · Journal of MOVE and Therapeutic Science · doi:10.37382/jomts.v1i1.11 · Cited by 1
Autonomic effects after anterior-to-posterior cervical mobilization.
de Araujo, F. X., Macagnan, F. E., Plentz, R. D. M., & Silva, M. F. (2015) · PubMed · Cited by 1
Herzratenvariabilität: Messung und Anwendungsmöglichkeiten in der Osteopathie
Günther-Borstel, J., Schmidt, T., & Liem, T. (2015) · Osteopathische Medizin · doi:10.1016/s1615-9071(15)30033-2
Upper cervical manual techniques and measures of autonomic nervous system control
Chippendale, E. (2013) · International journal of osteopathic medicine · doi:10.1016/j.ijosm.2013.04.009
January 2015 Letter to the Editor-in-Chief
de Araujo, F. X., Macagnan, F. E., Plentz, R. D. M., & Silva, M. F. (2015) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2015.0201
Posteroanterior Joint Mobilization for Cervical Somatic Dysfunction
Lee, P. J., & Seffinger, M. A. (2017) · Journal of Osteopathic Medicine · doi:10.7556/jaoa.2017.127
Peer Review #2 of "Combining motor imagery with action observation training does not lead to a greater autonomic nervous system response than motor imagery alone during simple and functional movements: a randomized controlled trial (v0.1)"
(2018) · PeerJ · doi:10.7287/peerj.5142v0.1/reviews/2

Authors: La Touche, R., París-Alemany, A., Mannheimer, J. S., Angulo-Díaz-Parreño, S., Bishop, M. D., Lopéz-Valverde-Centeno, A., von Piekartz, H., & Fernández-Carnero, J.
Affiliations: Columbia University (US)
University of Florida Health (US)
Universidad Europea de Madrid (ES)
ORCID: Bishop, Mark D.
von Piekartz, Harry
Venue: The Clinical Journal of Pain
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2013-03
Volume: 29
Issue: 3
Pages: 205-215
ISSN: 0749-8047 (ISSN-L)
DOI: 10.1097/ajp.0b013e318250f3cd
OpenAlex: W2156862303
Cited by: 112
References: 72
Citations by year: 2026: 3 · 2025: 4 · 2024: 7 · 2023: 12 · 2022: 7 · 2021: 6 · 2020: 16 · 2019: 12 · 2018: 13 · 2017: 7 · 2016: 9 · 2015: 11 · 2014: 3 · 2013: 2
FWCI: 2.42
Type: journal article
Language: en
Open access: closed
Locations: Clinical Journal of Pain (publishedVersion)
PubMed (publishedVersion)
ABACUS. Repositorio de Producción Científica (Universidad Europea) (submittedVersion)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Keywords: myofascial pain, pain modulation, pressure pain threshold, sympathetic nervous system, skin conductance, trigeminocervical complex, hypoalgesia, cervical manipulation
MeSH terms: Adult, Autonomic Nervous System, Cervical Vertebrae, Facial Pain, Female, Heart Rate, Humans, Male, Skin Temperature, Spain, Respiratory Mechanics, Treatment Outcome, Musculoskeletal Manipulations, Pain Perception

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Does Mobilization of the Upper Cervical Spine Affect Pain Sensitivity and Autonomic Nervous System Function in Patients With Cervico-craniofacial Pain?: A Randomized-controlled Trial

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