The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.
Statistical Evaluation of a Biomarker
Abstract
A biomarker may provide a diagnosis, assess disease severity or risk, or guide other clinical interventions such as the use of drugs. Although considerable progress has been made in standardizing the methodology and reporting of randomized trials, less has been accomplished concerning the assessment of biomarkers. Biomarker studies are often presented with poor biostatistics and methodologic flaws that precludes them from providing a reliable and reproducible scientific message. A host of issues are discussed that can improve the statistical evaluation and reporting of biomarker studies. Investigators should be aware of these issues when designing their studies, editors and reviewers when analyzing a manuscript, and readers when interpreting results.
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Cites
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Basic principles of ROC analysis
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Cited by
Hatib, F., Jian, Z., Buddi, S., Lee, C., Settels, J., Sibert, K., Rinehart, J., & Cannesson, M. (2018) · Anesthesiology · doi:10.1097/aln.0000000000002300 · Cited by 614
Cannesson, M., Le Manach, Y., Hofer, C. K., Goarin, J. P., Lehot, J.-J., Vallet, B., & Tavernier, B. (2011) · Anesthesiology · doi:10.1097/aln.0b013e318225b80a · Cited by 554
Deiuliis, J. A. (2016) · International Journal of Obesity · doi:10.1038/ijo.2015.170 · Cited by 349
Savin, I. A., Zenkova, M. A., & Sen’kova, A. V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314959 · Cited by 279
Lemay, K. R., Tulloch, H. E., Pipe, A. L., & Reed, J. L. (2019) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000379 · Cited by 280
Metadata
- Authors
- Ray, P., Manach, Y. L., Riou, B., Houle, T. T., & Warner, D. S.
- Venue
- Anesthesiology
- Published
- 2010-04-01
- Volume
- 112
- Issue
- 4
- Pages
- 1023-1040
- ISSN
- 0003-3022 (ISSN-L)
- OpenAlex
- W2080564894
- Cited by
- 503
- References
- 88
- FWCI
- 22.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ray, P., Manach, Y. L., Riou, B., Houle, T. T., & Warner, D. S. (2010). Statistical Evaluation of a Biomarker. Anesthesiology. https://doi.org/10.1097/aln.0b013e3181d47604
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
