Cited by 114Burn Injury Management and OutcomesAntioxidant Activity and Oxidative StressVitamin C and Antioxidants Research

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Supplementation of Vitamin E, Vitamin C, and Zinc Attenuates Oxidative Stress in Burned Children: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Barbosa, Eliana, Faintuch, Joel, Machado Moreira, Emilia Addison, Gonçalves da Silva, Viviane Rodrigues, Lopes Pereima, Maurício José, Martins Fagundes, Regina Lúcia, Filho, Danilo Wilhelm·2009·Journal of Burn Care & Research

DOI 10.1097/bcr.0b013e3181b487a8

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Abstract

The aim of this study was to investigate the effect of supplementation of vitamin E, vitamin C, and zinc on the oxidative stress in burned children. In a prospective double-blind placebo controlled pilot study, 32 patients were randomized as no supplementation (n = 15) or antioxidant supplementation (n = 17) groups. Supplementation consisted of the antioxidant mixture of vitamin C (1.5 times upper intake level), vitamin E (1.35 times upper intake level), and zinc (2.0 times recommended dietary allowance) administered during 7 days starting on the second day of admittance into the hospital. Energy requirement was calculated by the Curreri equation, and protein input was 3.0 g/kg of ideal body mass index (percentile 50). Total antioxidant capacity of plasma and malondialdehyde were used to monitor oxidative stress. The time of wound healing was evaluated as the main clinical feature. Patients (age 54.2 +/- 48.9 months, 65.6% males), who exhibited 15.5 +/- 6.7% of total burn area, showed no differences in age and sex, when compared with controls. Intake of the administered antioxidants was obviously higher in treated subjects (P = .005), and serum differences were confirmed for vitamin E and C, but not for zinc (P = .180). There was a decrease in lipid peroxidation (malondialdehyde level) (P = .006) and an increase in vitamin E concentrations in the antioxidant supplementation group (P = .016). The time of wound healing was lower in the supplemented group (P < .001). The antioxidant supplementation through vitamin E and C and the mineral zinc apparently enhanced antioxidant protection against oxidative stress and allowed less time for wound healing.

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Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial
(1999) · The Lancet · doi:10.1016/s0140-6736(99)07072-5 · Cited by 3,812
A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates
Miller, N. J., Rice-Evans, C. A., Davies, M. J., Gopinathan, V., & Milner, A. D. (1993) · Clinical Science · doi:10.1042/cs0840407 · Cited by 3,108
A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress
Rio, D. D., Stewart, A. J., & Pellegrini, N. (2005) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2005.05.003 · Cited by 2,789
Atomic Absorption Spectrometry
Robinson, J. W., Frame, E. S., & Frame, G. M., II (2014) · CRC Press eBooks · doi:10.1201/b15921-10 · Cited by 1,221
Total antioxidant capacity as a tool to assess redox status: critical view and experimental data.
Ghiselli, A., Serafini, M., Natella, F., & Scaccini, C. (2000) · Free Radical Biology & Medicine · doi:10.1016/s0891-5849(00)00394-4 · Cited by 1,112
Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general Practice
Roncaglioni, M. C. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03539-x · Cited by 993
Randomized, Prospective Trial of Antioxidant Supplementation in Critically Ill Surgical Patients
Nathens, A. B., Neff, M. J., Jurkovich, G. J., Klotz, P., Farver, K., RUZINSKI, J. T., Radella, F., Garcia, I. A., & Maier, R. V. (2002) · Annals of Surgery · doi:10.1097/00000658-200212000-00014 · Cited by 544
Free Radicals in Biology and Medicine 4th ed.
Halliwell, B. B., & Gutteridge, J. M. C. (2007) · Cited by 517
Methods in clinical chemistry
Pesce, A. J., & Kaplan, L. A. (1987) · Mosby eBooks · Cited by 452
Reduction of Resuscitation Fluid Volumes in Severely Burned Patients Using Ascorbic Acid Administration: A Randomized, Prospective Study
Tanaka, H. (2000) · Archives of Surgery · doi:10.1001/archsurg.135.3.326 · Cited by 438

Show all 39 references

Research works printed but not linked: 8

Jutkiewicz-Sypniewska, 2006, Adv Med Sci, 51, 316
Lehr, 2006, Eur J Med Res, 11, 516
Day, 1986, Proc Am Burn Assoc, 18, 86
Prelack, 2001, J Trauma, 51, 601
Goodarzi, 2008, Saudi Med J, 29, 503
Fischer, 1999, Am J Physiol, 276, H2194
Shepherd, 2003, Nurs Stand, 18, 55
Scholl, 2001, J Intraven Nurs, 24, 124

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Nutrient plasma levels achieved during treatment that reduces noise-induced hearing loss
Prell, C. G. L., Dolan, D. F., Bennett, D. C., & Boxer, P. A. (2011) · Translational research · doi:10.1016/j.trsl.2011.02.003 · Cited by 33
Effects of Vitamin and Amino Acid-Enriched Hyaluronic Acid Gel on the Healing of Oral Mucosa: In Vivo and In Vitro Study
Canciani, E., Sirello, R., Pellegrini, G., Henin, D., Perrotta, M., Toma, M., Khomchyna, N., & Dellavia, C. P. B. (2021) · Medicina · doi:10.3390/medicina57030285 · Cited by 32
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Ellinger, S. (2013) · Advances in Wound Care · doi:10.1089/wound.2013.0482 · Cited by 31
A randomized double-blind clinical trial to evaluate the efficacy of chlorhexidine, antioxidant, and hyaluronic acid mouthwashes in the management of biofilm-induced gingivitis.
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Stucki, P., Perez, M., Cotting, J., Shenkin, A., & Berger, M. M. (2010) · Critical Care · doi:10.1186/cc9198 · Cited by 16
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Leichtle, S. W., Sarma, A. K., Strein, M., Yajnik, V., Rivet, D. J., Sima, A. P., & Brophy, G. M. (2019) · Neurocritical Care · doi:10.1007/s12028-019-00829-x · Cited by 16
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Use of antioxidants in oral healthcare.
Miguel, S. M. S., Opperman, L. A., Allen, E. P., & Svoboda, K. K. H. (2011) · PubMed · Cited by 13
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[Advances in the knowledge of the use of micronutrients in artificial nutrition].
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Micronutrients
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Vitamin and trace element homeostasis following severe burn injury
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Nutrition artificielle en réanimation
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Clinical Management of Shock
Eiseman, B. (1985) · Archives of Surgery · doi:10.1001/archsurg.1985.01390280093028 · Cited by 3
Infectious and Inflammatory Disorders
Tsukahara, H., Yashiro, M., Nagaoka, Y., & Morishima, T. (2014) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-1-4939-0679-6_22 · Cited by 3
Dietary intake and Biochemical Indicators and their association with Wound Healing Process among Adult Burned Patients in the Gaza Strip
HAMMAD, S. M., Naser, I. A., Taleb, M., & Abutair, A. S. (2019) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.7.1.17 · Cited by 2
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Enas, A. E. (2023) · Tropical biomedicine · doi:10.47665/tb.40.2.012 · Cited by 2
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Ellinger, S. (2015) · Springer eBooks · doi:10.1007/978-1-4614-7836-2_49 · Cited by 2
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Aiko, S. (2014) · Springer eBooks · doi:10.1007/978-1-4614-8503-2_117-1 · Cited by 1
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Underdown, M. J. (2013) · Digital Commons - East Tennessee State University (East Tennessee State University) · Cited by 1
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Aiko, S. (2015) · Springer eBooks · doi:10.1007/978-1-4614-7836-2_117 · Cited by 1
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Baranwal, N., Gong, J. H., Arnoff, T. E., & Mehrzad, R. (2024) · European Journal of Plastic Surgery · doi:10.1007/s00238-024-02165-6 · Cited by 1
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Tsukahara, H. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_36 · Cited by 1
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Castro, C. C. (2013) · Enfermería Global · doi:10.6018/eglobal.12.3.152041 · Cited by 1
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Leichtle, S. W., Almohaish, S., Sandler, M., Yajnik, V., Rivet, D. J., Kashiouris, M. G., Fowler, A. A., & Brophy, G. M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-89835-5.00040-5 · Cited by 1
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Hardway, R. M. (1970) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-197002000-00045 · Cited by 1
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de Diego‐Otero, Y., Quintero-Navarro, C., Medina, R. C., Heredia‐Farfan, R., Salido, L. S., Lima‐Cabello, E., Higuero-Tapiador, A., Del, I., Fernández-Carvajal, I., Ferrando-Lucas, T., et al. (2012) · InTech eBooks · doi:10.5772/29480
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Wilson, R. F. (1985) · JAMA · doi:10.1001/jama.1985.03360080103042
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Perro, G. (2016) · Europe PMC (PubMed Central)
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lecturer, W. H. A. A. A. (2017) · IOSR Journal of Nursing and health Science · doi:10.9790/1959-0601056579

Authors: Barbosa, E., Faintuch, J., Machado Moreira, E. A., Gonçalves da Silva, V. R., Lopes Pereima, M. J., Martins Fagundes, R. L., & Filho, D. W.
Affiliations: Universidade Federal de Santa Catarina (BR)
Universidade de São Paulo (BR)
ORCID: Barbosa, Eliana
Filho, Danilo Wilhelm
Venue: Journal of Burn Care & Research
Publisher: Oxford University Press (OUP)
Published: 2009-09
Volume: 30
Issue: 5
Pages: 859-866
ISSN: 1559-047X (ISSN-L)
DOI: 10.1097/bcr.0b013e3181b487a8
OpenAlex: W2075521402
Cited by: 114
References: 39
Citations by year: 2026: 1 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 9 · 2021: 8 · 2020: 8 · 2019: 9 · 2018: 9 · 2017: 5 · 2016: 4 · 2015: 5 · 2014: 11 · 2013: 11 · 2012: 4
FWCI: 3.82
Type: journal article
Language: en
Open access: closed
Locations: Journal of Burn Care & Research (publishedVersion)
PubMed (publishedVersion)
Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico) (publishedVersion)
Topics: Health Sciences › Medicine › Surgery › Burn Injury Management and Outcomes
Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
Keywords: burns, pediatric burns, antioxidant supplementation, vitamin E, vitamin C, zinc, oxidative stress, lipid peroxidation, malondialdehyde, total antioxidant capacity, wound healing
MeSH terms: Adolescent, Analysis of Variance, Ascorbic Acid, Burns, Child, Child, Preschool, Double-Blind Method, Female, Humans, Male, Pilot Projects, Placebos, Prospective Studies, Vitamin E, Wound Healing, Zinc, Chi-Square Distribution, Treatment Outcome, Oxidative Stress, Statistics, Nonparametric

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Supplementation of Vitamin E, Vitamin C, and Zinc Attenuates Oxidative Stress in Burned Children: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

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