Natural Antioxidants from Plant Extracts in Skincare Cosmetics: Recent Applications, Challenges and Perspectives
Open accessAbstract
In recent years, interest in the health effects of natural antioxidants has increased due to their safety and applicability in cosmetic formulation. Nevertheless, efficacy of natural antioxidants in vivo is less documented than their prooxidant properties in vivo. Plant extracts rich in vitamins, flavonoids, and phenolic compounds can induce oxidative damage by reacting with various biomolecules while also providing antioxidant properties. Because the biological activities of natural antioxidants differ, their effectiveness for slowing the aging process remains unclear. This review article focuses on the use of natural antioxidants in skincare and the possible mechanisms underlying their desired effect, along with recent applications in skincare formulation and their limitations.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cosmeceuticals are a growing sector of the personal care industry.
“Cosmeceuticals are a growing sector of the personal care industry [2].”
From Licorice (Glycyrrhiza glabra, G. uralensis, and G. inflata) and Their Constituents as Active Cosmeceutical Ingredients (2022) · cites this paper as [2]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
No citation lists for this paper
No citation lists for this paper yet — checked again daily.
References 226 · Cited by 329
Research works printed but not linked: 120
- Abels, C.; Angelova-Fischer, I. Skin Care Products: Age-Appropriate Cosmetics. Curr. Probl. Dermatol. 2018, 54, 173-182. [CrossRef] [PubMed] · DOI
- Nilforoushzadeh, M.A.; Amirkhani, M.A.; Zarintaj, P.; Ms, A.S.M.; Mehrabi, T.; Alavi, S.; Sisakht, M.M. Skin care and rejuvenation by cosmeceutical facial mask. J. Cosmet. Dermatol. 2018, 17, 693-702. [CrossRef] [PubMed] · DOI
- Yosipovitch, G.; Misery, L.; Proksch, E.; Metz, M.; Ständer, S.; Schmelz, M. Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions. Acta Derm. Venereol. 2019, 99, 1201-1209. [CrossRef] · DOI
- Husein el Hadmed, H.; Castillo, R.F. Cosmeceuticals: Peptides, proteins, and growth factors. J. Cosm. Dermatol. 2016, 15, 514-519. [CrossRef] [PubMed] · DOI
- Thiyagarasaiyar, K.; Goh, B.-H.; Jeon, Y.-J.; Yow, Y.-Y. Algae Metabolites in Cosmeceutical: An Overview of Current Applications and Challenges. Mar. Drugs 2020, 18, 323. [CrossRef] [PubMed] · DOI
- Veeresham, C. Natural products derived from plants as a source of drugs. J. Adv. Pharm. Technol. Res. 2012, 3, 200-201. [CrossRef] · DOI
- Fowler, J.F., Jr.; Woolery-Lloyd, H.; Waldorf, H.; Saini, R. Innovations in natural ingredients and their use in skin care. J. Drugs Dermatol. 2010, 9 (Suppl. S6), S72-S81. [PubMed]
- Jesumani, V.; Du, H.; Aslam, M.; Pei, P.; Huang, N. Potential Use of Seaweed Bioactive Compounds in Skincare-A Review. Mar. Drugs 2019, 17, 688. [CrossRef] [PubMed] · DOI
- Bowe, W.P. Advances in natural ingredients and their use in skin care. Introduction. J. Drugs Dermatol. 2013, 12, s122. [PubMed]
- Speit, G. How to assess the mutagenic potential of cosmetic products without animal tests? Mutat. Res. Toxicol. Environ. Mutagen. 2009, 678, 108-112. [CrossRef] [PubMed] · DOI
- Hameury, S.; Borderie, L.; Monneuse, J.; Skorski, G.; Pradines, D. Prediction of skin anti-aging clinical benefits of an association of ingredients from marine and maritime origins: Ex vivo evaluation using a label-free quantitative proteomic and customized data processing approach. J. Cosmet. Dermatol. 2018, 18, 355-370. [CrossRef] · DOI
- Sumpio, B.E.; Cordova, A.C.; Berke-Schlessel, D.W.; Qin, F.; Chen, Q.H. Green tea, the "Asian paradox," and cardiovascular disease. J. Am. Coll. Surg. 2006, 202, 813-825. [CrossRef] [PubMed] · DOI
- Trovato, M.; Ballabio, C. Botanical products: General aspects. In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects; Springer: Cham, Switzerland, 2018; pp. 3-26.
- Koch, W.; Zagórska, J.; Marzec, Z.; Kukula-Koch, W. Applications of Tea (Camellia sinensis) and its Active Constituents in Cosmetics. Molecules 2019, 24, 4277. [CrossRef] [PubMed] · DOI
- Kottner, J.; Lichterfeld, A.; Blume-Peytavi, U. Maintaining skinintegrity in the aged: A systematic review. Br. J. Dermatol. 2013, 169, 528-542. [CrossRef] [PubMed] · DOI
- De Lima Cherubim, D.J.; Buzanello Martins, C.V.; Oliveira Fariña, L.; da Silva de Lucca, R.A. Polyphenols as natural antioxidants in cosmetics applications. J. Cosmet. Dermatol. 2020, 19, 33-37. [CrossRef] [PubMed] · DOI
- Silva, S.; Ferreira, M.; Oliveira, A.S.; Magalhaes, C.; Sousa, M.E.; Pinto, M.; Sousa Lobo, J.M.; Almeida, I.F. Evolution of the use of anti-oxidants in anti-ageing cosmetics. Int. J. Cosmet. Sci. 2019, 41, 378-386. [CrossRef] [PubMed] · DOI
- Babbush, K.; Babbush, R.; Khachemoune, A. The Therapeutic Use of Antioxidants for Melasma. J. Drugs Dermatol. 2020, 19, 788-792. [CrossRef] [PubMed] · DOI
- Augustyniak, A.; Bartosz, G.; Čipak, A.; Duburs, G.; Horáková, L.U.; Łuczaj, W.; Majekova, M.; Odysseos, A.D.; Rackova, L.; Skrzydlewska, E.; et al. Natural and synthetic antioxidants: An updated overview. Free Radic. Res. 2010, 44, 1216-1262. [CrossRef] [PubMed] · DOI · Paper page
- Kim, J.J.; Kim, K.S.; Yu, B.J. Optimization of Antioxidant and Skin-Whitening Compounds Extraction Condition from Tenebrio molitor Larvae (Mealworm). Molecules 2018, 23, 2340. [CrossRef] · DOI
- Zhang, S.; Duan, E. Fighting against skin aging: The way from bench to bedside. Cell Transplant. 2018, 27, 729-738. [CrossRef] [PubMed] · DOI · Paper page
- Farage, M.A.; Miller, K.W.; Elsner, P.; Maibach, H.I. Intrinsic and extrinsic factors in skin ageing: A review. Int. J. Cosmet. Sci. 2008, 30, 87-95. [CrossRef] [PubMed] · DOI · Paper page
- Rees, J.L. The Genetics of Sun Sensitivity in Humans. Am. J. Hum. Genet. 2004, 75, 739-751. [CrossRef] [PubMed] · DOI
- Krutmann, J.; Schikowski, T.; Morita, A.; Berneburg, M. Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms. J. Investig. Dermatol. 2021, 141, 1096-1103. [CrossRef] · DOI · Paper page
- Coppé, J.P.; Desprez, P.Y.; Krtolica, A.; Campisi, J. The senescence-associated secretory phenotype: The dark side of tumor suppres-sion. Annu. Rev. Pathol. Mech. Dis. 2010, 5, 99-118. [CrossRef] · DOI · Paper page
- Flament, F.; Bazin, R.; Qiu, H.; Ye, C.; Laquieze, S.; Rubert, V.; Decroux, A.; Simonpietri, E.; Piot, B. Solar exposure(s) and facial clinical signs of aging in Chinese women: Impacts upon age perception. Clin. Cosmet. Investig. Dermatol. 2015, 8, 75-84. [CrossRef] · DOI
- Morais, M.L.; Silva, A.C.; Araújo, C.R.; Esteves, E.A.; Dessimoni-Pinto, N.A. Determinação do potencial antioxidante in vitro de frutos do cerrado brasileiro. Rev. Bras. Fruticult. 2013, 35, 355-360. [CrossRef] · DOI
- Bose, B.; Choudhury, H.; Tandon, P.; Kumaria, S. Studies on secondary metabolite profiling, anti-inflammatory potential, in vitro photoprotective and skin-aging related enzyme inhibitory activities of Malaxis acuminata, a threatened orchid of nutraceutical importance. J. Photochem. Photobiol. B Biol. 2017, 173, 686-695. [CrossRef] · DOI
- Leopoldini, M.; Russo, N.; Toscano, M. The molecular basis of working mechanism of natural polyphenolic antioxidants. Food Chem. 2011, 125, 288-306. [CrossRef] · DOI
- Cavinato, M.; Waltenberger, B.; Baraldo, G.; Grade, C.V.; Stuppner, H.; Jansen-Dürr, P. Plant extracts and natural compounds used against UVB-induced photoaging. Biogerontology 2017, 18, 499-516. [CrossRef] [PubMed] · DOI · Paper page
- Pisoschi, A.M.; Pop, A. The Role of Antioxidants in the Chemistry of Oxidative Stress: A review. Eur. J. Med. Chem. 2015, 97, 55-74. [CrossRef] · DOI
- Aune, D. Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence. Adv. Nutr. 2019, 10, S404-S421. [CrossRef] · DOI
- Xu, D.-P.; Li, Y.; Meng, X.; Zhou, T.; Zhou, Y.; Zheng, J.; Zhang, J.-J.; Li, H.-B. Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources. Int. J. Mol. Sci. 2017, 18, 96. [CrossRef] [PubMed] · DOI
- Jenab, M.; Riboli, E.; Ferrari, P.; Sabate, J.; Slimani, N.; Norat, T.; Friesen, M.; Tjonneland, A.; Olsen, A.; Overvad, K.; et al. Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Carcinogenesis 2006, 27, 2250-2257. [CrossRef] · DOI
- Li, A.-N.; Li, S.; Zhang, Y.-J.; Xu, X.-R.; Chen, Y.-M.; Li, H.-B. Resources and Biological Activities of Natural Polyphenols. Nutrients 2014, 6, 6020-6047. [CrossRef] · DOI
- Salomone, F.; Godos, J.; Zelber-Sagi, S. Natural antioxidants for non-alcoholic fatty liver disease: Molecular targets and clinical perspectives. Liver Int. 2016, 36, 5-20. [CrossRef] [PubMed] · DOI
- Balmus, I.M.; Ciobica, A.; Trifan, A.; Stanciu, C. The implications of oxidative stress and antioxidant therapies in Inflammatory Bowel Disease: Clinical aspects and animal models. Saudi J. Gastroenterol. 2016, 22, 3-17. [CrossRef] · DOI
- Khan, B.A.; Mahmood, T.; Menaa, F.; Shahzad, Y.; Yousaf, A.M.; Hussain, T.; Ray, S.D. New Perspectives on the Efficacy of Gallic Acid in Cosmetics & Nanocosmeceuticals. Curr. Pharm. Des. 2019, 24, 5181-5187. [CrossRef] · DOI
- Neha, K.; Haider, R.; Pathak, A.; Yar, M.S. Medicinal prospects of antioxidants: A review. Eur. J. Med. Chem. 2019, 178, 687-704. [CrossRef] [PubMed] · DOI
- Valko, M.; Leibfritz, D.; Moncol, J.; Cronin, M.T.; Mazur, M.; Telser, J. Free Radicals and Antioxidants in Normal Physiological Functions and Human Disease. Int. J. Biochem. Cell Biol. 2007, 39, 44-84. [CrossRef] [PubMed] · DOI · Paper page
- Nalimu, F.; Oloro, J.; Kahwa, I.; Ogwang, P.E. Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox. Futur. J. Pharm. Sci. 2021, 7, 1-21. [CrossRef] [PubMed] · DOI
- Burke, K.E. Protection From Environmental Skin Damage With Topical Antioxidants. Cl. Pharmacol. Ther. 2018, 105, 36-38. [CrossRef] [PubMed] · DOI
- Pandey, K.B.; Rizvi, S.I. Plant Polyphenols as Dietary Antioxidants in Human Health and Disease. Oxid. Med. Cell. Longev. 2009, 2, 270-278. [CrossRef] [PubMed] · DOI
- Cartea, M.E.; Francisco, M.; Soengas, P.; Velasco, P. Phenolic Compounds in Brassica Vegetables. Molecules 2010, 16, 251-280. [CrossRef] [PubMed] · DOI
- Rao, S.; Kurakula, M.; Mamidipalli, N.; Tiyyagura, P.; Patel, B.; Manne, R. Pharmacological Exploration of Phenolic Compound: Raspberry Ketone-Update 2020. Plants 2021, 10, 1323. [CrossRef] [PubMed] · DOI
- De Oliveira Raphaelli, C.; Azevedo, J.G.; dos Santos Pereira, E.; Vinholes, J.R.; Camargo, T.M.; Hoffmann, J.F.; Ribeiro, J.A.; Vizzotto, M.; Rombaldi, C.V.; Wink, M.R.; et al. Phenolic-rich apple extracts have photoprotective and anti-cancer effect in dermal cells. Phytomed. Plus. 2021, 1, 100112. [CrossRef] · DOI
- Rabelo, A.C.S.; Costa, D. A review of biological and pharmacological activities of Baccharis trimera. Chem. Interact. 2018, 296, 65-75. [CrossRef] · DOI
- Sikora, M.; Złotek, U.; Kordowska-Wiater, M.; Świeca, M. Effect of Basil Leaves and Wheat Bran Water Extracts on Antioxidant Capacity, Sensory Properties and Microbiological Quality of Shredded Iceberg Lettuce during Storage. Antioxidants 2020, 9, 355. [CrossRef] [PubMed] · DOI
- Anand, U.; Tudu, C.K.; Nandy, S.; Sunita, K.; Tripathi, V.; Loake, G.J.; Dey, A.; Proćków, J. Ethnodermatological use of medicinal plants in India: From ayurvedic formulations to clinical perspectives-A review. J. Ethnopharmacol. 2021, 284, 114744. [CrossRef] [PubMed] · DOI
- Curutchet, A.; Cozzano, S.; Tárrega, A.; Arcia, P. Blueberry pomace as a source of antioxidant fibre in cookies: Consumer's ex-pectations and critical attributes for developing a new product. Food Sci. Technol. Int. 2019, 25, 642-648. [CrossRef] [PubMed] · DOI
- Routray, W.; Orsat, V. Blueberries and Their Anthocyanins: Factors Affecting Biosynthesis and Properties. Compr. Rev. Food Sci. Food Saf. 2011, 10, 303-320. [CrossRef] · DOI
- Chaves-Gómez, J.L.; Cotes-Prado, A.M.; Gómez-Caro, S.; Restrepo-Díaz, H. Physiological Response of Cape Gooseberry Seedlings to Two Organic Additives and Their Mixture under Inoculation with Fusarium oxysporum f. sp. physali. HortScience 2020, 55, 55-62. [CrossRef] · DOI
- Hassanien, M.F.R.; Serag, H.M.; Qadir, M.S.; Ramadan, M.F. Cape gooseberry (Physalis peruviana) juice as a modulator agent for hepatocellular carcinoma-linked apoptosis and cell cycle arrest. Biomed. Pharmacother. 2017, 94, 1129-1137. [CrossRef] [PubMed] · DOI
- Zerres, S.; Stahl, W. Carotenoids in human skin. Biochim. Biophys. Acta BBA-Mol. Cell Biol. Lipids. 2020, 1865, 158588. [CrossRef] [PubMed] · DOI
- Pinto, D.; Vieira, E.F.; Peixoto, A.F.; Freire, C.; Freitas, V.; Costa, P.; Delerue-Matos, C.; Rodrigues, F. Optimizing the extraction of phenolic antioxidants from chestnut shells by subcritical water extraction using response surface methodology. Food Chem. 2020, 334, 127521. [CrossRef] [PubMed] · DOI
- Ribeiro, A.S.; Estanqueiro, M.; Oliveira, M.B.; Lobo, J.M.S. Main Benefits and Applicability of Plant Extracts in Skin Care Products. Cosmetics 2015, 2, 48-65. [CrossRef] · DOI
- Monteiro, Â.; Colomban, S.; Azinheira, H.G.; Guerra-Guimarães, L.; Silva, M.D.C.; Navarini, L.; Resmini, M. Dietary Antioxidants in Coffee Leaves: Impact of Botanical Origin and Maturity on Chlorogenic Acids and Xanthones. Antioxidants 2019, 9, 6. [CrossRef] · DOI
- Dos Santos, É.M.; de Macedo, L.M.; Tundisi, L.L.; Ataide, J.A.; Camargo, G.A.; Alves, R.C.; Oliveira, M.B.; Mazzola, P.G. Coffee by-products in topical formulations: A review. Trends Food Sci. Technol. 2021, 111, 280-291. [CrossRef] · DOI
- Sganzerla, W.G.; Ferreira, A.L.A.; Rosa, G.B.; Azevedo, M.S.; Ferrareze, J.P.; Komatsu, R.A.; Nunes, M.R.; Da Rosa, C.G.; Schmit, R.; Costa, M.D.; et al. Feijoa [Acca sellowiana (Berg) Burret] accessions characterization and discrimination by chemometrics. J. Sci. Food Agric. 2020, 100, 5373-5384. [CrossRef] [PubMed] · DOI
- Smeriglio, A.; Denaro, M.; De Francesco, C.; Cornara, L.; Barreca, D.; Bellocco, E.; Ginestra, G.; Mandalari, G.; Trombetta, D. Feijoa Fruit Peel: Micro-morphological Features, Evaluation of Phytochemical Profile, and Biological Properties of Its Essential Oil. Antioxidants 2019, 8, 320. [CrossRef] [PubMed] · DOI
- Fang, J.; Wang, Z.; Wang, P.; Wang, M. Extraction, structure and bioactivities of the polysaccharides from Ginkgo biloba: A review. Int. J. Biol. Macromol. 2020, 162, 1897-1905. [CrossRef] [PubMed] · DOI
- Wang, X.; Gong, X.; Zhang, H.; Zhu, W.; Jiang, Z.; Shi, Y.; Li, L. In vitro anti-aging activities of ginkgo biloba leaf extract and its chemical constituents. Food Sci. Technol. 2020, 40, 476-482. [CrossRef] · DOI
- Ma, Z.F.; Zhang, H.; Teh, S.S.; Wang, C.W.; Zhang, Y.; Hayford, F.; Wang, L.; Ma, T.; Dong, Z.; Zhang, Y.; et al. Goji Berries as a Potential Natural Antioxidant Medicine: An Insight into Their Molecular Mechanisms of Action. Oxid. Med. Cell. Longev. 2019, 2019, 2437397. [CrossRef] · DOI
- Medina, S.; Collado-González, J.; Ferreres, F.; Londoño-Londoño, J.; Jiménez-Cartagena, C.; Guy, A.; Durand, T.; Galano, J.M.; Gil- Izquierdo, Á. Potential of Physalis peruviana calyces as a low-cost valuable resource of phytoprostanes and phenolic com-pounds. J. Sci. Food Agric. 2019, 99, 2194-2204. [CrossRef] · DOI
- Nocetti, D.; Núñez, H.; Puente, L.; Espinosa, A.; Romero, F. Composition and biological effects of goldenberry byproducts: An overview. J. Sci. Food Agric. 2020, 100, 4335-4346. [CrossRef] · DOI
- Rauf, A.; Imran, M.; Butt, M.S.; Nadeem, M.; Peters, D.G.; Mubarak, M.S. Resveratrol as an anti-cancer agent: A review. Crit. Rev. Food Sci. Nutr. 2018, 58, 1428-1447. [CrossRef] [PubMed] · DOI
- Bito, T.; Okumura, E.; Fujishima, M.; Watanabe, F. Potential of Chlorella as a Dietary Supplement to Promote Human Health. Nutrients 2020, 12, 2524. [CrossRef] [PubMed] · DOI
- Dantas Silva, R.P.; Machado, B.A.; Barreto, G.D.; Costa, S.S.; Andrade, L.N.; Amaral, R.G.; Carvalho, A.A.; Padilha, F.F.; Barbosa, J.D.; Umsza-Guez, M.A. Antioxidant, antimicrobial, antiparasitic, and cytotoxic properties of various Brazilian propolis extracts. PLoS ONE 2017, 12, e0172585. [CrossRef] · DOI
- Berthon, J.-Y.; Kappes, R.N.; Bey, M.; Cadoret, J.-P.; Renimel, I.; Filaire, E. Marine algae as attractive source to skin care. Free. Radic. Res. 2017, 51, 555-567. [CrossRef] [PubMed] · DOI
- Carvalho, A.G.; Silva, K.A.; Silva, L.O.; Costa, A.M.; Akil, E.; Coelho, M.A.; Torres, A.G. Jussara berry (Euterpe edulis M.) oil-in-water emulsions are highly stable: The role of natural antioxidants in the fruit oil. J. Sci. Food Agric. 2019, 99, 90-99. [CrossRef] · DOI
- Lupatini, N.R.J.; Danopoulos, P.; Swikidisa, R.; Alves, P.V. Evaluation of the Antibacterial Activity of Green Propolis Extract and Meadowsweet Extract Against Staphylococcus aureus Bacteria: Importance in Would Care Compounding Preparations. Int. J. Pharm. Compd. 2016, 20, 333-337.
- Costanzo, G.; Iesce, M.R.; Naviglio, D.; Ciaravolo, M.; Vitale, E.; Arena, C. Comparative studies on different citrus cultivars: A re-valuation of waste mandarin components. Antioxidants 2020, 9, 517. [CrossRef] [PubMed] · DOI
- Braga, A.R.C.; Mesquita, L.M.D.S.; Martins, P.; Habu, S.; de Rosso, V.V. Lactobacillus fermentation of jussara pulp leads to the enzymatic conversion of anthocyanins increasing antioxidant activity. J. Food Compos. Anal. 2018, 69, 162-170. [CrossRef] · DOI
- Liu, N.; Li, X.; Zhao, P.; Zhang, X.; Qiao, O.; Huang, L.; Guo, L.; Gao, W. A review of chemical constituents and health-promoting effects of citrus peels. Food Chem. 2021, 365, 130585. [CrossRef] [PubMed] · DOI
- Umamahesh, K.; Gandhi, A.D.; Reddy, O.V. Ethnopharmacological Applications of Mango (Mangifera indica L.) Peel-A Review. Curr. Pharm. Biotechnol. 2020, 21, 1298-1303. [CrossRef] [PubMed] · DOI
- Patravale, V.; Mandawgade, S. Formulation and evaluation of exotic fat based cosmeceuticals for skin repair. Indian J. Pharm. Sci. 2008, 70, 539-542. [CrossRef] [PubMed] · DOI
- Safari, R.; Hoseinifar, S.H.; Van Doan, H.; Dadar, M. The effects of dietary Myrtle (Myrtus communis) on skin mucus immune parameters and mRNA levels of growth, antioxidant and immune related genes in zebrafish (Danio rerio). Fish. Shellfish Immunol. 2017, 66, 264-269. [CrossRef] [PubMed] · DOI
- Ozcan, O.; Ipekci, H.; Alev, B.; Ustundag, U.V.; Ak, E.; Sen, A.; Alturfan, E.E.; Sener, G.; Yarat, A.; Cetinel, S.; et al. Protective effect of Myrtle (Myrtus communis) on burn induced skin injury. Burns 2019, 45, 1856-1863. [CrossRef] [PubMed] · DOI
- Gorzynik-Debicka, M.; Przychodzen, P.; Cappello, F.; Kuban-Jankowska, A.; Gammazza, A.M.; Knap, N.; Wozniak, M.; Gorska- Ponikowska, M. Potential Health Benefits of Olive Oil and Plant Polyphenols. Int. J. Mol. Sci. 2018, 19, 686. [CrossRef] [PubMed] · DOI
- Danby, S.G.; AlEnezi, T.; Sultan, A.; Lavender, T.; Chittock, J.; Brown, K.; Cork, M.J. Effect of olive and sunflower seed oil on the adult skin barrier: Implications for neonatal skin care. Pediatr. Dermatol. 2013, 30, 42-50. [CrossRef] [PubMed] · DOI · Paper page
- Yap, J.Y.; Hii, C.L.; Ong, S.P.; Lim, K.H.; Abas, F.; Pin, K.Y. Effects of drying on total polyphenols content and antioxidant properties of Carica papaya leaves. J. Sci. Food Agric. 2020, 100, 2932-2937. [CrossRef] · DOI
- Sharma, A.; Bachheti, A.; Sharma, P.; Bachheti, R.K.; Husen, A. Phytochemistry, pharmacological activities, nanoparticle fabrication, commercial products and waste utilization of Carica papaya L.: A comprehensive review. Curr. Res. Biotechnol. 2020, 2, 145-160. [CrossRef] · DOI
- Drogoudi, P.; Gerasopoulos, D.; Kafkaletou, M.; Tsantili, E. Phenotypic characterization of qualitative parameters and antioxidant contents in peach and nectarine fruit and changes after jam preparation. J. Sci. Food Agric. 2017, 97, 3374-3383. [CrossRef] · DOI
- Noratto, G.; Porter, W.; Byrne, D.; Cisneros-Zevallos, L. Polyphenolics from peach (Prunus persica var. Rich Lady) inhibit tumor growth and metastasis of MDA-MB-435 breast cancer cells in vivo. J. Nutr. Biochem. 2014, 25, 796-800. [CrossRef] [PubMed] · DOI
- Gurbuz, N.; Uluişik, S.; Frary, A.; Frary, A.; Do ganlar, S. Health benefits and bioactive compounds of eggplant. Food Chem. 2018, 268, 602-610. [CrossRef] [PubMed] · DOI
- Topal, U.; Sasaki, M.; Goto, M.; Otles, S. Chemical compositions and antioxidant properties of essential oils from nine species of Turkish plants obtained by supercritical carbon dioxide extraction and steam distillation. Int. J. Food Sci. Nutr. 2008, 59, 619-634. [CrossRef] [PubMed] · DOI
- Ali, M.M.; Hashim, N.; Aziz, S.A.; Lasekan, O. Pineapple (Ananas comosus): A comprehensive review of nutritional values, volatile compounds, health benefits, and potential food products. Food Res. Int. 2020, 137, 109675. [CrossRef] · DOI
- Ajayi, A.M.; Coker, A.I.; Oyebanjo, O.T.; Adebanjo, I.M.; Ademowo, O.G. Ananas comosus (L) Merrill (pineapple) fruit peel extract demonstrates antimalarial, anti-nociceptive and anti-inflammatory activities in experimental models. J. Ethnopharmacol. 2021, 282, 114576. [CrossRef] [PubMed] · DOI
- Vučić, V.; Grabež, M.; Trchounian, A.; Arsić, A. Composition and Potential Health Benefits of Pomegranate: A Review. Curr. Pharm. Des. 2019, 25, 1817-1827. [CrossRef] · DOI
- Cervi, V.F.; Saccol, C.P.; Sari, M.H.M.; Martins, C.C.; da Rosa, L.S.; Ilha, B.D.; Soares, F.Z.; Luchese, C.; Wilhelm, E.A.; Cruz, L. Pullulan film incorporated with nanocapsules improves pomegranate seed oil anti-inflammatory and antioxidant effects in the treatment of atopic dermatitis in mice. Int. J. Pharm. 2021, 609, 121144. [CrossRef] [PubMed] · DOI
- Pasupuleti, V.R.; Sammugam, L.; Ramesh, N.; Gan, S.H. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxid. Med. Cell. Longev. 2017, 2017, 1259510. [CrossRef] 100. · DOI
- Abdellatif, M.M.; Elakkad, Y.E.; Elwakeel, A.A.; Allam, R.M.; Mousa, M.R. Formulation and characterization of propolis and tea tree oil nanoemulsion loaded with clindamycin hydrochloride for wound healing: In-vitro and in-vivo wound healing assessment. Saudi Pharm. J. 2021. [CrossRef] 101. Vega, J.; Bonomi-Barufi, J.; Gómez-Pinchetti, J.L.; Figueroa, F.L. Cyanobacteria and Red Macroalgae as Potential Sources of Anti-oxidants and UV Radiation-Absorbing Compounds for Cosmeceutical Applications. Mar. Drugs 2020, 18, 659. [CrossRef] 102. Aslam, A.; Bahadar, A.; Liaqat, R.; Saleem, M.; Waqas, A.; Zwawi, M. Algae as an attractive source for cosmetics to counter envi-ronmental stress. Sci. Total Environ. 2021, 772, 144905. [CrossRef] [PubMed] 103. Septembre-Malaterre, A.; Stanislas, G.; Douraguia, E.; Gonthier, M.-P. Evaluation of nutritional and antioxidant properties of the tropical fruits banana, litchi, mango, papaya, passion fruit and pineapple cultivated in Réunion French Island. Food Chem. 2016, 212, 225-233. [CrossRef] [PubMed] 104. Al-Mqbali, L.R.A.; Hossain, M.A. Cytotoxic and antimicrobial potential of different varieties of ripe banana used traditionally to treat ulcers. Toxicol. Rep. 2019, 6, 1086-1090. [CrossRef] [PubMed] 105. Bonifácio-Lopes, T.; Boas, A.A.; Coscueta, E.R.; Costa, E.M.; Silva, S.; Campos, D.; Teixeira, J.A.; Pintado, M. Bioactive extracts from brewer's spent grain. Food Funct. 2020, 11, 8963-8977. [CrossRef] [PubMed] 106. Connolly, A.; Cermeño, M.; Alashi, A.M.; Aluko, R.E.; FitzGerald, R.J. Generation of phenolic-rich extracts from brewers' spent grain and characterisation of their in vitro and in vivo activities. Innov. Food Sci. Emerg. Technol. 2021, 68, 102617. [CrossRef] 107. Kocaadam, B.; Şanlier, N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit. Rev. Food Sci. Nutr. 2015, 57, 2889-2895. [CrossRef] [PubMed] 108. · DOI
- Manuguerra, S.; Caccamo, L.; Mancuso, M.; Arena, R.; Rappazzo, A.C.; Genovese, L.; Santulli, A.; Messina, C.M.; Maricchiolo, G. The antioxidant power of horseradish, Armoracia rusticana, underlies antimicrobial and antiradical effects, exerted in vitro. Nat. Prod. Res. 2018, 34, 1567-1570. [CrossRef] [PubMed] 116. · DOI
- Saleem, S.; Muhammad, G.; Hussain, M.A.; Altaf, M.; Bukhari, S.N. Withania somnifera L.: Insights into the phytochemical profile, therapeutic potential, clinical trials, and future prospective. Iran. J. Basic Med. Sci. 2020, 23, 1501. [PubMed] 117. Kim, D.Y.; Kim, M.K.; Kim, B.-W. The Antioxidant and Skin Whitening Effect of Withania somnifera (Winter Cherry). J. Food Hyg. Saf. 2015, 30, 258-264. [CrossRef] 118. Lupo, M.P. Antioxidants and vitamins in cosmetics. Clin. Dermatol. 2001, 19, 467-473. [CrossRef] 119. Shapiro, S.S.; Saliou, C. Role of vitamins in skin care. Nutrition 2001, 17, 839-844. [CrossRef] 120. Lobo, V.; Patil, A.; Phatak, A.; Chandra, N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn. Rev. 2010, 4, 118-126. [CrossRef] 121. De Oliveira Pinto, C.A.; Martins, T.E.; Martinez, R.M.; Freire, T.B.; Velasco, M.V.; Baby, A.R. Vitamin E in Human Skin: Functionality and Topical Products; InTech Open: London, UK, 2021. 122. · DOI · Paper page
- Tozer, S.; O'Mahony, C.; Hannah, J.; O'Brien, J.; Kelly, S.; Kosemund-Meynen, K.; Alexander-White, C. Aggregate exposure modelling of vitamin A from cosmetic products, diet and food supplements. Food Chem. Toxicol. 2019, 131, 110549. [CrossRef] [PubMed] 123. Gaspar, L.R.; Campos, P.M.B.G.M. A HPLC method to evaluate the influence of photostabilizers on cosmetic formulations containing UV-filters and vitamins A and E. Talanta 2010, 82, 1490-1494. [CrossRef] [PubMed] 124. · DOI
- Alaluf, S.; Heinrich, U.; Stahl, W.; Tronnier, H.; Wiseman, S. Dietary Carotenoids Contribute to Normal Human Skin Color and UV Photosensitivity. J. Nutr. 2002, 132, 399-403. [CrossRef] [PubMed] 129. · DOI
- Köpcke, W.; Krutmann, J. Protection from Sunburn with β-Carotene-A Meta-analysis. Photochem. Photobiol. 2008, 84, 284-288. [CrossRef] [PubMed] 130. · DOI · Paper page
- Chiu, C.-J.; Taylor, A. Nutritional antioxidants and age-related cataract and maculopathy. Exp. Eye Res. 2007, 84, 229-245. [CrossRef] 131. Zizola, C.F.; Frey, S.K.; Jitngarmkusol, S.; Kadereit, B.; Yan, N.; Vogel, S. Cellular Retinol-Binding Protein Type I (CRBP-I) Regulates Adipogenesis. Mol. Cell. Biol. 2010, 30, 3412-3420. [CrossRef] [PubMed] 132. Darlenski, R.; Surber, C.; Fluhr, J.W. Topical retinoids in the management of photodamaged skin: From theory to evidence-based practical approach. Br. J. Dermatol. 2010, 163, 1157-1165. [CrossRef] 133. Sorg, O.; Kuenzli, S.; Kaya, G.; Saurat, J.-H. Proposed mechanisms of action for retinoid derivatives in the treatment of skin aging. J. Cosmet. Dermatol. 2005, 4, 237-244. [CrossRef] [PubMed] 134. Sorg, O.; Saurat, J.-H. Topical Retinoids in Skin Ageing: A Focused Update with Reference to Sun-Induced Epidermal Vitamin A Deficiency. Dermatology 2014, 228, 314-325. [CrossRef] [PubMed] 135. Shao, Y.; He, T.; Fisher, G.J.; Voorhees, J.J.; Quan, T. Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo. Int. J. Cosmet. Sci. 2016, 39, 56-65. [CrossRef] · DOI · Paper page
- Rossetti, D.; Kielmanowicz, M.G.; Vigodman, S.; Hu, Y.P.; Chen, N.; Nkengne, A.; Oddos, T.; Fischer, D.; Seiberg, M.; Lin, C.B. A novel anti-ageing mechanism for retinol: Induction of dermal elastin synthesis and elastin fibre formation. Int. J. Cosmet. Sci. 2011, 33, 62-69. [CrossRef] [PubMed] 137. · DOI · Paper page
- Kligman, A.M.; Grove, G.L.; Hirose, R.; Leyden, J.J. Topical tretinoin for photoaged skin. J. Am. Acad. Dermatol. 1986, 15, 836-859. [CrossRef] 138. Bauer, E.A.; Seltzer, J.L.; Eisen, A.Z. Retinoic Acid Inhibition of Collagenase and Gelatinase Expression in Human Skin Fibroblast Cultures. Evidence for a Dual Mechanism. J. Investig. Dermatol. 1983, 81, 162-169. [CrossRef] 139. Michalak, M.; Pierzak, M.; Kręcisz, B.; Suliga, E. Bioactive Compounds for Skin Health: A Review. Nutrients 2021, 13, 203. [CrossRef] 140. Everts, H.B. Endogenous retinoids in the hair follicle and sebaceous gland. Biochim. Biophys. Acta Mol. Cell Biol. Lipids 2012, 1821, 222-229. [CrossRef] [PubMed] 141. Mukherjee, S.; Date, A.; Patravale, V.; Korting, H.C.; Roeder, A.; Weindl, G. Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clin. Interv. Aging 2006, 1, 327-348. [CrossRef] 142. Dawson, M.I.; Hobbs, P.D.; Peterson, V.J.; Leid, M.; Lange, C.W.; Feng, K.C.; Chen, G.Q.; Gu, J.; Li, H.; Kolluri, S.K.; et al. Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity. Cancer Res. 2001, 61, 4723-4730. 143. Duvic, M.; Nagpal, S.; Asano, A.T.; Chandraratna, R.A. Molecular mechanisms of tazarotene action in psoriasis. J. Am. Acad. Dermatol. 1997, 37, S18-S24. [CrossRef] 144. Tanno, O.; Ota, Y.; Kitamura, N.; Katsube, T.; Inoue, S. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br. J. Dermatol. 2000, 143, 524-531. [CrossRef] [PubMed] 145. · DOI
- Forbat, E.; Al-Niaimi, F.; Ali, F.R. Use of nicotinamide in dermatology. Clin. Exp. Dermatol. 2017, 42, 137-144. [CrossRef] [PubMed] 146. · DOI
- Bains, P.; Kaur, M.; Kaur, J.; Sharma, S. Nicotinamide: Mechanism of action and indications in dermatology. Indian J. Dermatol. Venereol. Leprol. 2018, 84, 234-237. [CrossRef] [PubMed] 147. · DOI
- Seemal Desai, M.D.; Eloisa Ayres, M.D.; Hana Bak, M.D.; Green, B.S.; PhDg, Q.Z. Effect of a tranexamic acid, kojic acid, and niacin-amide containing serum on facial dyschromia: A clinical evaluation. J. Drugs Dermatol. 2019, 18, 454-459. 148. Cosmetic Ingredient Review Expert Panel. Final report of the safety assessment of niacinamide and niacin. Int. J. Toxicol. 2005, 24, 1-31. 149.
- Caritá, A.C.; Fonseca-Santos, B.; Shultz, J.D.; Michniak-Kohn, B.; Chorilli, M.; Leonardi, G.R. Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability. Nanomed. Nanotechnol. Biol. Med. 2020, 24, 102117. [CrossRef] [PubMed] 150. · DOI
- Sunil Kumar, B.V.; Singh, S.; Verma, R. Anticancer potential of dietary vitamin D and ascorbic acid: A review. Crit. Rev. Food Sci. Nutr. 2017, 57, 2623-2635. [CrossRef] [PubMed] 151. Lin, J.-Y.; Selim, M.; Shea, C.R.; Grichnik, J.M.; Omar, M.M.; Monteiro-Riviere, N.; Pinnell, S.R. UV photoprotection by combination topical antioxidants vitamin C and vitamin E. J. Am. Acad. Dermatol. 2003, 48, 866-874. [CrossRef] [PubMed] 152. Mastrangelo, D.; Pelosi, E.; Castelli, G.; Lo-Coco, F.; Testa, U. Mechanisms of anti-cancer effects of ascorbate: Cytotoxic activity and epigenetic modulation. Blood CellsMol. Dis. 2018, 69, 57-64. [CrossRef] [PubMed] 153. · DOI
- Shearer, M.J.; Bach, A.; Kohlmeier, M. Chemistry, nutritional sources, tissue distribution and metabolism of vitamin K with special reference to bone health. J. Nutr. 1996, 126, 1181S-1186S. [CrossRef] [PubMed] 163. Fitzmaurice, S.; Sivamani, R.; Isseroff, R. Antioxidant Therapies for Wound Healing: A Clinical Guide to Currently Commercially Available Products. Ski. Pharmacol. Physiol. 2011, 24, 113-126. [CrossRef] [PubMed] 164. Ghorbanzadeh, B.; Nemati, M.; Behmanesh, M.A.; Hemmati, A.A.; Houshmand, G. Topical vitamin K1promotes repair of full thickness wound in rat. Indian J. Pharmacol. 2014, 46, 409-412. [CrossRef] [PubMed] 165. · DOI
- Katiyar, S.K.; Afaq, F.; Azizuddin, K.; Mukhtar, H. Inhibition of UVB-induced oxidative stress-mediated phosphorylation of mi-togen-activated protein kinase signaling pathways in cultured human epidermal keratinocytes by green tea polyphenol (-)-epigallocatechin-3-gallate. Toxicol. Appl. Pharmacol. 2001, 176, 110-117. [CrossRef] [PubMed] 171. Afaq, F.; Adhami, V.M.; Ahmad, N.; Mukhtar, H. Inhibition of ultraviolet B-mediated activation of nuclear factor κB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate. Oncogene 2003, 22, 1035-1044. [CrossRef] [PubMed] 172. Michna, L.; Lu, Y.-P.; Lou, Y.-R.; Wagner, G.C.; Conney, A.H. Stimulatory effect of oral administration of green tea and caffeine on locomotor activity in SKH-1 mice. Life Sci. 2003, 73, 1383-1392. [CrossRef] 173. Laine, A.-L. Resistance variation within and among host populations in a plant-pathogen metapopulation: Implications for regional pathogen dynamics. J. Ecol. 2004, 92, 990-1000. [CrossRef] 174. Afaq, F.; Adhami, V.M.; Ahmad, N. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicol. Appl. Pharmacol. 2003, 186, 28-37. [CrossRef] 175. Cao, C.; Lu, S.; Kivlin, R.; Wallin, B.; Card, E.; Bagdasarian, A.; Tamakloe, T.; Wang, W.J.; Song, X.; Chu, W.M.; et al. SIRT1 confers protection against UVB-and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. J. Cell. Mol. Med. 2009, 13, 3632-3643. [CrossRef] [PubMed] 176. · DOI
- Thimmulappa, R.K.; Mai, K.H.; Srisuma, S.; Kensler, T.W.; Yamamoto, M.; Biswal, S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 2002, 62, 5196-5203. [PubMed] 177. Suh, J.H.; Shenvi, S.V.; Dixon, B.M.; Liu, H.; Jaiswal, A.K.; Liu, R.M.; Hagen, T.M. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc. Natl. Acad. Sci. USA 2004, 101, 3381-3386. [CrossRef] 178. Kubo, E.; Chhunchha, B.; Singh, P.; Sasaki, H.; Singh, D.P. Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci. Rep. 2017, 7, 14130. [CrossRef] [PubMed] 179. · DOI
- Heo, S.-J.; Ko, S.-C.; Cha, S.-H.; Kang, D.-H.; Park, H.-S.; Choi, Y.-U.; Kim, D.; Jung, W.-K.; Jeon, Y.-J. Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol. Vitr. 2009, 23, 1123-1130. [CrossRef] [PubMed] 185. · DOI
- Heo, S.-J.; Jeon, Y.-J. Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage. J. Photochem. Photobiol. B Biol. 2009, 95, 101-107. [CrossRef] 186. Hur, S.; Lee, H.; Kim, Y.; Lee, B.-H.; Shin, J.; Kim, T.-Y. Sargaquinoic acid and sargachromenol, extracts of Sargassum sagamianum, induce apoptosis in HaCaT cells and mice skin: Its potentiation of UVB-induced apoptosis. Eur. J. Pharmacol. 2008, 582, 1-11. [CrossRef] [PubMed] 187. · DOI
- Bałan, B.J.; Niemcewicz, M.; Kocik, J.; Jung, L.; Skopi ńska-Ró żewska, E.; Skopi ński, P. Oral administration of Aloe vera gel, an-ti-microbial and anti-inflammatory herbal remedy, stimulates cell-mediated immunity and antibody production in a mouse model. Cent. Eur. J. Immunol. 2014, 39, 125. [CrossRef] [PubMed] 188. · DOI
- Hęś, M.; Dziedzic, K.; Górecka, D.; Jędrusek-Goli ńska, A.; Gujska, E. Aloe vera (L.) Webb.: Natural sources of antioxidants-A review. Plant. Foods Hum. Nutr. 2019, 74, 255-265. [CrossRef] 189. Hajheidari, Z.; Saeedi, M.; Morteza-Semnani, K.; Soltani, A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: A randomized, double-blind, prospective trial. J. Dermatol. Treat. 2013, 25, 123-129. [CrossRef] [PubMed] 190. · DOI
- Kitture, R.; Ghosh, S.; More, P.A.; Date, K.; Gaware, S.; Datar, S.; Chopade, B.A.; Kale, S.N. Curcumin-Loaded, Self-Assembled Aloevera Template for Superior Antioxidant Activity and Trans-Membrane Drug Release. J. Nanosci. Nanotechnol. 2015, 15, 4039-4045. [CrossRef] [PubMed] 191. Arct, J.; Pytkowska, K. Flavonoids as components of biologically active cosmeceuticals. Clin. Dermatol. 2008, 26, 347-357. [CrossRef] 192. Maleki, S.J.; Crespo, J.F.; Cabanillas, B. Anti-inflammatory effects of flavonoids. Food Chem. 2019, 299, 125124. [CrossRef] 193. Procházková, D.; Boušová, I.; Wilhelmová, N. Antioxidant and prooxidant properties of flavonoids. Fitoterapia 2011, 82, 513-523. [CrossRef] [PubMed] 194. · DOI
- Weber, J.M.; Ruzindana-Umunyana, A.; Imbeault, L.; Sircar, S. Inhibition of adenovirus infection and adenain by green tea catechins. Antivir. Res. 2002, 58, 167-173. [CrossRef] 195. Alvesalo, J.; Vuorela, H.; Tammela, P.; Leinonen, M.; Saikku, P. Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures. Biochem. Pharmacol. 2006, 71, 735-741. [CrossRef] [PubMed] 196. Subarnas, A.; Wagner, H. Analgesic and anti-inflammatory activity of the proanthocyanidin shellegueain A from Polypodium feei METT. Phytomedicine 2000, 7, 401-405. [CrossRef] 197. Mladěnka, P.; Zatloukalová, L.; Filipský, T.; Hrdina, R. Cardiovascular effects of flavonoids are not caused only by direct antiox-idant activity. Free Radic. Biol. Med. 2010, 49, 963-975. [CrossRef] [PubMed] 198. Kostelac, D.; Rechkemmer, G.; Briviba, K. Phytoestrogens Modulate Binding Response of Estrogen Receptors α and β to the Estrogen Response Element. J. Agric. Food Chem. 2003, 51, 7632-7635. [CrossRef] [PubMed] 199. · DOI
- Kuiper, G.G.J.M.; Lemmen, J.G.; Carlsson, B.; Corton, J.C.; Safe, S.H.; Van Der Saag, P.T.; Van Der Burg, B.; Gustafsson, J. Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β. Endocrinology 1998, 139, 4252-4263. [CrossRef] [PubMed] 200. Guardia, T.; Rotelli, A.E.; Juarez, A.O.; Pelzer, L.E. Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat. Farmaco 2001, 56, 683-687. [CrossRef] 201. Virgili, F.; Kobuchi, H.; Packer, L. Nitrogen monoxide (NO) metabolism antioxidant properties and modulation of inducible NO synthase activity in activated macrophages by procyanidins extracted from Pinus maritima (Pycnogenol). Free Radic. Biol. Med. 1998, 24, 1120-1129. [CrossRef] 202. Kempuraj, D.; Madhappan, B.; Christodoulou, S.; Boucher, W.; Cao, J.; Papadopoulou, N.; Cetrulo, C.L.; Theoharides, T.C. Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. Br. J. Pharmacol. 2005, 145, 934-944. [CrossRef] 203. Marzocchella, L.; Fantini, M.; Benvenuto, M.; Masuelli, L.; Tresoldi, I.; Modesti, A.; Bei, R. Dietary Flavonoids: Molecular Mechanisms of Action as Anti-Inflammatory Agents. Recent Pat. Inflamm. Allergy Drug Discov. 2011, 5, 200-220. [CrossRef] [PubMed] 204. Kumazawa, Y.; Takimoto, H.; Matsumoto, T.; Kawaguchi, K. Potential Use of Dietary Natural Products, Especially Polyphenols, for Improving Type-1 Allergic Symptoms. Curr. Pharm. Des. 2014, 20, 857-863. [CrossRef] [PubMed] 205. Tanaka, T.; Takahashi, R. Flavonoids and Asthma. Nutrients 2013, 5, 2128-2143. [CrossRef] 206. Finn, D.F.; Walsh, J.J. Twenty-first century mast cell stabilizers. Br. J. Pharmacol. 2013, 170, 23-37. [CrossRef] [PubMed] 207. · DOI
- Gibis, M.; Zeeb, B.; Weiss, J. Formation, characterization, and stability of encapsulated hibiscus extract in multilayered liposomes. Food Hydrocoll. 2013, 38, 28-39. [CrossRef] 215. Kaur, C.D.; Saraf, S. Topical vesicular formulations of Curcuma longa extract on recuperating the ultraviolet radiation-damaged skin. J. Cosmet. Dermatol. 2011, 10, 260-265. [CrossRef] [PubMed] 216. Moulaoui, K.; Caddeo, C.; Manca, M.L.; Castangia, I.; Valenti, D.; Escribano, E.; Atmani, D.; Fadda, A.M.; Manconi, M. Identification and nanoentrapment of polyphenolic phytocomplex from Fraxinus angustifolia: In vitro and in vivo wound healing potential. Eur. J. Med. Chem. 2015, 89, 179-188. [CrossRef] [PubMed] 217. Takahashi, M.; Kitamoto, D.; Asikin, Y.; Takara, K.; Wada, K. Liposomes encapsulating Aloe vera leaf gel extract significantly en-hance proliferation and collagen synthesis in human skin cell lines. J. Oleo Sci. 2009, 58, 643-650. [CrossRef] 218. · DOI
- Aisha, A.F.; Majid, A.M.; Ismail, Z. Preparation and characterization of nano liposomes of Orthosiphon stamineus ethanolic extract in soybean phospholipids. BMC Biotechnol. 2014, 14, 23. [CrossRef] [PubMed] 219. · DOI
- Spigno, G.; Donsì, F.; Amendola, D.; Sessa, M.; Ferrari, G.; De Faveri, D.M. Nanoencapsulation systems to improve solubility and antioxidant efficiency of a grape marc extract into hazelnut paste. J. Food Eng. 2013, 114, 207-214. [CrossRef] 220. Tsai, W.C.; Li, W.C.; Yin, H.Y.; Yu, M.C.; Wen, H.W. Constructing liposomal nanovesicles of ginseng extract against hydrogen per-oxide-induced oxidative damage to L929 cells. Food Chem. 2012, 132, 744-751. [CrossRef] 221. Kwon, S.S.; Kim, S.Y.; Kong, B.J.; Kim, K.J.; Noh, G.Y.; Im, N.R.; Lim, J.W.; Ha, J.H.; Kim, J.; Park, S.N. Cell penetrating peptide conjugated liposomes as transdermal delivery system of Polygonum aviculare L. extract. Int. J. Pharm. 2015, 483, 26-37. [CrossRef] 222. · DOI
- Mahdi, E.S.; Sakeena, M.H.; Abdulkarim, M.F.; Sattar, M.A.; Noor, A.M.; Abdullah, G.Z. Formulation and in vitro release evaluation of newly synthesized palm kernel oil esters-based nanoemulsion delivery system for 30% ethanolic dried extract derived from local Phyllanthus urinaria for skin antiaging. Int. J. Nanomed. 2011, 6, 2499-2512. [CrossRef] [PubMed] 223. · DOI
- Zorzi, G.K.; Caregnato, F.F.; Moreira, J.C.F.; Teixeira, H.F.; Carvalho, E.L.S. Antioxidant Effect of Nanoemulsions Containing Extract of Achyrocline satureioides (Lam) D.C.-Asteraceae. AAPS PharmSciTech 2015, 17, 844-850. [CrossRef] [PubMed] · DOI · Paper page
- Authors
- Hoang, H. T., Moon, J.-Y., & Lee, Y.-C.
- Affiliations
- Gachon University (KR)
- Hansung University (KR)
- Corresponding author
- Moon, Ju-Young
- Lee, Young-Chul
- Venue
- Cosmetics
- Publisher
- MDPI AG
- Published
- 2021-11-10
- Volume
- 8
- Issue
- 4
- Pages
- 106
- ISSN
- 2079-9284 (ISSN-L)
- OpenAlex
- W3213264976
- Cited by
- 329
- References
- 226
- Citations by year
- 2026: 58 · 2025: 106 · 2024: 80 · 2023: 54 · 2022: 29 · 2021: 2
- FWCI
- 36.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cosmetics (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- natural antioxidants, plant extracts, skin care products, flavonoids, phenolic compounds, oxidative damage, aging, cosmetic formulation, pro-oxidant activity, skin aging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review