The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Autograft, Allograft, and Bone Graft Substitutes: Clinical Evidence and Indications for Use in the Setting of Orthopaedic Trauma Surgery
Abstract
Summary: Bone grafts are the second most common tissue transplanted in the United States, and they are an essential treatment tool in the field of acute and reconstructive traumatic orthopaedic surgery. Available in cancellous, cortical, or bone marrow aspirate form, autogenous bone graft is regarded as the gold standard in the treatment of posttraumatic conditions such as fracture, delayed union, and nonunion. However, drawbacks including donor-site morbidity and limited quantity of graft available for harvest make autograft a less-than-ideal option for certain patient populations. Advancements in allograft and bone graft substitutes in the past decade have created viable alternatives that circumvent some of the weak points of autografts. Allograft is a favorable alternative for its convenience, abundance, and lack of procurement-related patient morbidity. Options include structural, particulate, and demineralized bone matrix form. Commonly used bone graft substitutes include calcium phosphate and calcium sulfate synthetics—these grafts provide their own benefits in structural support and availability. In addition, different growth factors including bone morphogenic proteins can augment the healing process of bony defects treated with grafts. Autograft, allograft, and bone graft substitutes all possess their own varying degrees of osteogenic, osteoconductive, and osteoinductive properties that make them better suited for different procedures. It is the purpose of this review to characterize these properties and present clinical evidence supporting their indications for use in the hopes of better elucidating treatment options for patients requiring bone grafting in an orthopaedic trauma setting.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Morbidity at Bone Graft Donor Sites
Younger, E. M., & Chapman, M. W. (1989) · Journal of Orthopaedic Trauma · doi:10.1097/00005131-198909000-00002 · Cited by 2,012
Carragee, E. J., Hurwitz, E. L., & Weiner, B. K. (2011) · The Spine Journal · doi:10.1016/j.spinee.2011.04.023 · Cited by 1,395
GOVENDER, S., CSIMMA, C., GENANT, H. K., & VALENTIN-OPRAN, A. (2002) · The Journal of Bone and Joint Surgery-American Volume · doi:10.2106/00004623-200212000-00001 · Cited by 1,308
BONE-GRAFTING AND BONE-GRAFT SUBSTITUTES
FINKEMEIER, C. G. (2002) · The Journal of Bone and Joint Surgery-American Volume · doi:10.2106/00004623-200203000-00020 · Cited by 1,099
The Biology of Bone Graft Repair
BURCHARDT, H. (1983) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-198304000-00005 · Cited by 1,078
The Concept of Induced Membrane for Reconstruction of Long Bone Defects
Masquelet, A. C., & Begue, T. (2010) · Orthopedic Clinics of North America · doi:10.1016/j.ocl.2009.07.011 · Cited by 860
Dimitriou, R., Mataliotakis, G. I., Angoules, A. G., Kanakaris, N. K., & Giannoudis, P. V. (2011) · Injury · doi:10.1016/j.injury.2011.06.015 · Cited by 858
Khan, S. N., Cammisa, F. P., Sandhu, H. S., Diwan, A. D., Girardi, F. P., & Lane, J. M. (2005) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/00124635-200501000-00010 · Cited by 857
Hernigou, P. (2005) · The Journal of Bone and Joint Surgery (American) · doi:10.2106/jbjs.d.02215 · Cited by 787
Bone-Graft Substitutes: Facts, Fictions, and Applications
Greenwald, A. S., Boden, S. D., Goldberg, V. M., Khan, Y., Laurencin, C. T., & Rosier, R. N. (2001) · The Journal of Bone and Joint Surgery-American Volume · doi:10.2106/00004623-200100022-00007 · Cited by 703
Cited by
Natural and Synthetic Polymers for Bone Scaffolds Optimization
Donnaloja, F., Jacchetti, E., Soncini, M., & Raimondi, M. T. (2020) · Polymers · doi:10.3390/polym12040905 · Cited by 324
Tan, S. H. S., Wong, J. R. Y., Sim, S. J. Y., Tjio, C. K. E., Wong, K. L., Chew, J. R. J., Hui, J. H. P., & Toh, W. S. (2020) · Materials Today Bio · doi:10.1016/j.mtbio.2020.100067 · Cited by 152
Nanoclay-composite hydrogels for bone tissue engineering
Hwang, H. S., & Lee, C.-S. (2024) · Gels · doi:10.3390/gels10080513 · Cited by 60
Rupp, M., Klute, L., Baertl, S., Walter, N., Mannala, G., Frank, L., Pfeifer, C., Alt, V., & Kerschbaum, M. (2022) · Journal of Biomedical Materials Research Part B: Applied Biomaterials · doi:10.1002/jbm.b.34911 · Cited by 58
Lu, H., Zhang, Y., Xiong, S., Zhou, Y., Xiao, L., Ma, Y., Xiao, Y., & Wang, X. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.699802 · Cited by 36
Metadata
- Authors
- Baldwin, P., Li, D. J., Auston, D. A., Mir, H. S., Yoon, R. S., & Koval, K. J.
- Venue
- Journal of Orthopaedic Trauma
- Published
- 2019-04
- Volume
- 33
- Issue
- 4
- Pages
- 203-213
- ISSN
- 0890-5339 (ISSN-L)
- OpenAlex
- W2909816341
- Cited by
- 773
- References
- 45
- FWCI
- 40.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Autograft, Allograft, and Bone Graft Substitutes: Clinical Evidence and Indications for Use in the Setting of Orthopaedic Trauma Surgery. https://app.cochat.ai/papers/10.1097/bot.0000000000001420
- The paper
- Baldwin, P., Li, D. J., Auston, D. A., Mir, H. S., Yoon, R. S., & Koval, K. J. (2019). Autograft, Allograft, and Bone Graft Substitutes: Clinical Evidence and Indications for Use in the Setting of Orthopaedic Trauma Surgery. Journal of Orthopaedic Trauma. https://doi.org/10.1097/bot.0000000000001420
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
