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Cited by 438

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Physical Therapy for the Critically Ill in the ICU: A Systematic Review and Meta-Analysis*

Kayambu, Geetha, Boots, Robert, Paratz, Jennifer·2013·Critical Care Medicine

Abstract

OBJECTIVE: The purpose of this systematic review was to review the evidence base for exercise in critically ill patients. DATA SOURCES AND STUDY SELECTION: Using keywords critical care and physical therapy and related synonyms, randomized controlled trials, meta-analyses, and systematic reviews were identified through electronic database searches and citation tracking. Clinical trials with outcomes of mortality, length of hospital and ICU stay, physical function and quality of life, muscle strength, and ventilator-free days were included. DATA EXTRACTION AND SYNTHESIS: Two reviewers abstracted data and assessed quality independently. Effect sizes and 95% confidence intervals were calculated. From 3,126 screened abstracts, 10 randomized controlled trials and five reviews were found. The mean Physiotherapy Evidence Database score was 5.4. Overall there was a significant positive effect favoring physical therapy for the critically ill to improve the quality of life (g = 0.40, 95% confidence interval 0.08, 0.71), physical function (g = 0.46, 95% confidence interval 0.13, 0.78), peripheral muscle strength (g = 0.27, 95% confidence interval 0.02, 0.52), and respiratory muscle strength (g = 0.51, 95% confidence interval 0.12, 0.89). Length of hospital (g = -0.34, 95% confidence interval -0.53, -0.15) and ICU stay (g = -0.34, 95% confidence interval -0.51, -0.18) significantly decreased and ventilator-free days increased (g = 0.38, 95% confidence interval 0.16, 0.59) following physical therapy in the ICU. There was no effect on mortality. CONCLUSION: Physical therapy in the ICU appears to confer significant benefit in improving quality of life, physical function, peripheral and respiratory muscle strength, increasing ventilator-free days, and decreasing hospital and ICU stay. However, further controlled trials of better quality and larger sample sizes are required to verify the strength of these tentative associations.

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Metadata

Authors
Kayambu, G., Boots, R., & Paratz, J.
Venue
Critical Care Medicine
Published
2013-06
Volume
41
Issue
6
Pages
1543-1554
ISSN
0090-3493 (ISSN-L)
OpenAlex
W2051978755
Cited by
438
References
65
FWCI
31.33
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Physical Therapy for the Critically Ill in the ICU: A Systematic Review and Meta-Analysis*. https://app.cochat.ai/papers/10.1097/ccm.0b013e31827ca637
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Kayambu, G., Boots, R., & Paratz, J. (2013). Physical Therapy for the Critically Ill in the ICU: A Systematic Review and Meta-Analysis*. Critical Care Medicine. https://doi.org/10.1097/ccm.0b013e31827ca637

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