Cited by 29Blood Pressure and Hypertension StudiesCardiovascular Health and Disease PreventionCardiovascular Function and Risk Factors

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Home and ambulatory blood pressure monitoring in children, adolescents and young adults: comparison, diagnostic agreement and association with preclinical organ damage

Abstract

Objectives: To compare the association of home (HBP), ambulatory (ABP) and office blood pressure (OBP) measurements with preclinical organ damage in young individuals. Methods: Individuals referred for elevated blood pressure and healthy volunteers aged 6–25 years were evaluated with OBP (2–3 visits), 7-day HBP and 24-h ABP monitoring. Organ damage was assessed by echocardiographic left ventricular mass index (LVMI), carotid ultrasonography [intima--media thickness (IMT)] and pulse wave velocity (PWV) using piezo-electronic or oscillometric technique. Results: Analysis included 251 individuals (mean age 14 ± 3.9 years, 70.9% men: 31.1% children, 54.6% adolescents, 14.3% young adults) of whom 189 had LVMI, 123 IMT and 198 PWV measurements. Office, ambulatory and home hypertension was diagnosed in 29.5, 27.1 and 26.3% of participants. The agreement of OBP with ABP was 74.5% (kappa 0.37) and HBP 76.1% (kappa 0.41), with closer agreement between HBP and ABP (84.9%, kappa 0.61). LVMI gave comparable correlations with systolic OBP, 24-h ABP and HBP ( r = 0.31/0.31/0.30, all P < 0.01). The same was the case for IMT (0.33/0.32/0.37, all P < 0.01) and piezo-electronic PWV (0.55/0.53/0.52, all P < 0.01), whereas oscillometric PWV gave stronger correlations with OBP than ABP or HBP. In linear regression analysis, the variation of LVMI was determined by night-time ABP, of IMT by HBP and of PWV by OBP and 24-h ABP. Conclusion: These data suggest that in young individuals, target organ damage is mainly determined by out-of-office rather than office BP. Home and ambulatory BP give comparable associations with preclinical organ damage.

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Metadata

Authors
Zeniodi, M. E., Ntineri, A., Kollias, A., Servos, G., Moyssakis, I., Destounis, A., Harokopakis, A., Vazeou, A., & Stergiou, G. S.
Affiliations
  • National and Kapodistrian University of Athens (GR)
  • Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital
  • Panagiotis & Aglaia Kyriakou Children's Hospital (GR)
  • Laiko General Hospital of Athens (GR)
  • Hygeia Hospital (GR)
Corresponding author
  • Zeniodi, Maria Elena
  • Ntineri, Angeliki
Venue
Journal of Hypertension
Published
2020-06
Volume
38
Issue
6
Pages
1047-1055
ISSN
  • 0263-6352 (ISSN-L)
  • 1473-5598
OpenAlex
W3007678587
Cited by
29
References
7
Citations by year
2026: 3 · 2025: 7 · 2024: 1 · 2023: 8 · 2022: 6 · 2021: 3 · 2020: 1
FWCI
2.82
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Hypertension (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords
home blood pressure monitoring, ambulatory blood pressure monitoring, office blood pressure, hypertension diagnosis, left ventricular mass, carotid intima-media thickness, pulse wave velocity, children and adolescents, young adults, out-of-office blood pressure, diagnostic agreement
MeSH terms
Adolescent, Adult, Ambulatory Care, Blood Pressure Determination, Child, Humans, Hypertension, Reproducibility of Results, Blood Pressure Monitoring, Ambulatory, Young Adult, Carotid Intima-Media Thickness, Pulse Wave Analysis

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