The DOI matches its Crossref record; 55 of the 57 references it cites were found in a registry or an index.
Relation of blood pressure and body mass index during childhood to cardiovascular risk factor levels in young adults
Open accessAbstract
INTRODUCTION: Adult obesity and hypertension are leading causes of cardiovascular morbidity/mortality. Although childhood BMI and blood pressure (BP) track into adulthood, how they influence adult cardiovascular risk independent of each other is not well defined. METHODS: Participants were from two longitudinal studies with a baseline evaluation at mean age of 13 years and a follow-up at mean age of 24 years. Regression models using childhood BP and BMI to predict young adult cardiovascular risk factors were performed. RESULTS: In univariate analysis, childhood BMI predicted young adult BP, lipids, glucose, insulin and insulin resistance, whereas childhood BP predicted young adult BP, lipids and glucose. In a multivariable regression model (adjusted for age, sex and race), which included change in BMI and BP from age 13 to 24 years, BMI predicted all young adult risk factors except BP and glucose. Baseline SBP predicted young adult BP, cholesterol, triglycerides and glucose whereas baseline DBP predicted young adult BP, BMI and glucose. CONCLUSION: The results from this study show that BP and BMI act independently in children to influence future cardiovascular risk factors and the combination of high BP and BMI in childhood has an additive effect in predicting the highest levels of young adult cardiovascular risk. Thus, there should be a focus on treating hypertension in overweight and obese children, in addition to attempting to reduce weight.
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“Factors that increase cardiovascular risk have been shown to emerge early in life.”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [187]
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“For example, blood pressure and body mass index in adolescence predict future adult cardiovascular risk (187).”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [187]
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Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961
Prevalence of Overweight and Obesity in the United States, 1999-2004
Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720
National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) · PEDIATRICS · doi:10.1542/peds.114.2.s2.555 · Cited by 6,913
Prevalence and Trends in Overweight Among US Children and Adolescents, 1999-2000
Ogden, C. L. (2002) · JAMA · doi:10.1001/jama.288.14.1728 · Cited by 4,060
Obesity and the risk of heart failure
Kenchaiah, S., Evans, J. C., Levy, D., Wilson, P. W. F., Benjamin, E. J., Larson, M. G., Kannel, W. B., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020245 · Cited by 3,093
Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome
Wajchenberg, B. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0415 · Cited by 2,961
Fox, C. S., Massaro, J. M., Hoffmann, U., Pou, K. M., Maurovich-Horvat, P., Liu, C.-Y., Vasan, R. S., Murabito, J. M., Meigs, J. B., Cupples, L. A., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.675355 · Cited by 2,882
Skinfold equations for estimation of body fatness in children and youth.
Slaughter, M. H., Lohman, T. G., Boileau, R. A., Horswill, C. A., Stillman, R. J., Loan, M. D. V., & Bemben, D. A. (1988) · PubMed · Cited by 2,712
Reactive oxygen species have a causal role in multiple forms of insulin resistance
Houstis, N., Rosen, E. D., & Lander, E. S. (2006) · Nature · doi:10.1038/nature04634 · Cited by 2,525 · cited 1×
“While a cause-effect relationship has not been documented in humans thus far, in mice it has been shown that reactive oxygen species increase before the development of insulin resistance [40].”
BackgroundFreedman, D. S., Khan, L. K., Dietz, W. H., Srinivasan, S. R., & Berenson, G. S. (2001) · PEDIATRICS · doi:10.1542/peds.108.3.712 · Cited by 1,359
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Minneapolis Childhood Cohort Studies
Urbina, E. M., & Sinaiko, A. R. (2026) · Contemporary cardiology · doi:10.1007/978-3-032-14256-6_16
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Metadata
- Authors
- Rademacher, E. R., Jacobs, D. R., Moran, A., Steinberger, J., Prineas, R. J., & Sinaiko, A.
- Affiliations
- University of Rochester Medicine (US)
- University of Minnesota (US)
- Wake Forest University Health Sciences (US)
- Corresponding author
- Rademacher, Erin R
- Venue
- Journal of Hypertension
- Published
- 2009-09
- Volume
- 27
- Issue
- 9
- Pages
- 1766-1774
- ISSN
- 0263-6352 (ISSN-L)
- PMC
- PMC2886129
- OpenAlex
- W2118259361
- Cited by
- 101
- References
- 57
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 7 · 2021: 9 · 2020: 5 · 2019: 2 · 2018: 6 · 2017: 5 · 2016: 7 · 2015: 11 · 2014: 7 · 2013: 10 · 2012: 6
- FWCI
- 4.76
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Hypertension (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Aging
- National Heart, Lung, and Blood Institute (R01HL034659, R01HL052851, HL-52851)
- National Center for Research Resources (M01RR000400, M01-RR00400)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- childhood blood pressure, childhood body mass index, childhood obesity, pediatric hypertension, cardiovascular risk factors, young adults, serum lipids, glucose, insulin resistance
- MeSH terms
- Adolescent, Adult, Aging, Blood Glucose, Blood Pressure, Cardiovascular Diseases, Child, Female, Humans, Insulin Resistance, Longitudinal Studies, Male, Obesity, Risk Factors, Body Mass Index, Lipid Metabolism, Young Adult
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