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Low cardiorespiratory fitness is a strong predictor for clustering of cardiovascular disease risk factors in children independent of country, age and sex

Open access
Anderssen, Sigmund A., Cooper, Ashley R., Riddoch, Chris, Sardinha, Luis B., Harro, Maarike, Brage, Søren, Andersen, Lars B.·2007·European Journal of Cardiovascular Prevention & Rehabilitation

Abstract

Background and design: Few studies have investigated the association between maximal cardiorespiratory capacity (fitness) and the clustered cardiovascular disease (CVD) risk in children and youth from culturally diverse countries. This cross-sectional study examined the association between fitness and clustered CVD risk in children and adolescents from three European countries. Methods: Participants were 2845 randomly selected school children aged 9 or 15 years from Portugal ( n = 944), Denmark ( n = 849) and Estonia ( n = 1052). Cardiorespiratory fitness was determined during a maximal test on a cycle ergometer. CVD risk factors selected to assess the degree of clustering were the total cholesterol/high-density lipoprotein cholesterol ratio, plasma triglycerides, insulin resistance (homeostasis model assessment), sum of four skinfolds, and systolic blood pressure. Results: There was a strong association between cardiorespiratory fitness and the clustering of CVD risk factors. The odds ratios for clustering in each quartile of fitness, using the quartile with the highest fitness as reference, were 13.0 [95% confidence interval (CI) 8.8-19.1]; 4.8 (95% CI 3.2-7.1) and 2.5 (95% CI 1.6-3.8), respectively, after adjusting for country, age, sex, socio-economic status, pubertal stage, family history of CVD and diabetes. In stratified analyses by age group, sex and country, similar strong patterns were observed. Conclusion: Low cardiorespiratory fitness is strongly associated with the clustering of CVD risk factors in children independent of country, age and sex.

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Metadata

Authors
Anderssen, S. A., Cooper, A. R., Riddoch, C., Sardinha, L. B., Harro, M., Brage, S., & Andersen, L. B.
Venue
European Journal of Cardiovascular Prevention & Rehabilitation
Published
2007-08
Volume
14
Issue
4
Pages
526-531
ISSN
1741-8267 (ISSN-L)
OpenAlex
W1993341184
Cited by
315
References
4
FWCI
9.10
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Low cardiorespiratory fitness is a strong predictor for clustering of cardiovascular disease risk factors in children independent of country, age and sex. https://app.cochat.ai/papers/10.1097/hjr.0b013e328011efc1
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Anderssen, S. A., Cooper, A. R., Riddoch, C., Sardinha, L. B., Harro, M., Brage, S., & Andersen, L. B. (2007). Low cardiorespiratory fitness is a strong predictor for clustering of cardiovascular disease risk factors in children independent of country, age and sex. European Journal of Cardiovascular Prevention & Rehabilitation. https://doi.org/10.1097/hjr.0b013e328011efc1

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