Cited by 272Geriatric Care and Nursing HomesHealth Systems, Economic Evaluations, Quality of LifeAging, Health, and Disability

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The Relationship of 60 Disease Diagnoses and 15 Conditions to Preference-Based Health-Related Quality of Life in Ontario Hospital-Based Long-Term Care Residents

Lam, Jonathan M. C., Wodchis, Walter P.·2010·Medical Care

DOI 10.1097/mlr.0b013e3181ca2647

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Abstract

BACKGROUND: Population-based diagnosis- and condition-specific health-related quality of life (HRQoL) scores are required for decision-making and research purposes. These HRQoL scores do not exist for hospital-based long-term care (LTC) residents. OBJECTIVE: To estimate the impact of 60 diseases and 15 conditions on caregiver-assessed preference-based HRQoL. METHODS: Residents in hospital-based LTC facilities in Ontario, Canada were identified from administrative databases containing resident minimum data set (MDS) assessments completed between August 1st, 2003 and March 31st, 2008. A preference-based HRQoL measure, the MDS Health-Status Index (MDS-HSI) score, was calculated for 66,193 residents. Average MDS-HSI scores and multivariate linear regression models were used to estimate the impact of the diagnoses and conditions, respectively. RESULTS: After adjusting for age, sex, and other diagnoses, aphasia exhibited the largest negative relationship to the MDS-HSI (-0.085), followed by cancer (-0.072) and Alzheimer disease (-0.062). Cancer was also the second most prevalent diagnosis (27.6%). Lack of balance was a common condition (87.3%) and it had the greatest negative relationship to MDS-HSI scores among the 15 conditions (-0.099). The diagnoses and conditions regression models had R values of 0.12 and 0.34, respectively, suggesting that clinical conditions provided better explanatory variables for the MDS-HSI than diagnoses. CONCLUSIONS: The findings suggest that diseases affect preference-based HRQoL differently in a hospital-based LTC population compared with previous studies in the general population. The population-based MDS-HSI scores from this study can be used as reference values in cost-effectiveness analyses for hospital-based LTC populations.

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Authors: Lam, J. M. C., & Wodchis, W. P.
Affiliations: University of Toronto (CA)
Corresponding author: Lam, Jonathan M. C.
Wodchis, Walter P.
ORCID: Wodchis, Walter P.
Venue: Medical Care
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-04
Volume: 48
Issue: 4
Pages: 380-387
ISSN: 0025-7079 (ISSN-L)
DOI: 10.1097/mlr.0b013e3181ca2647
OpenAlex: W1987557314
Cited by: 272
References: 31
Citations by year: 2026: 26 · 2025: 34 · 2024: 25 · 2023: 34 · 2022: 28 · 2021: 26 · 2020: 26 · 2019: 13 · 2018: 9 · 2017: 15 · 2016: 8 · 2015: 12 · 2014: 4 · 2013: 5 · 2012: 5
FWCI: 6.84
Type: journal article
Language: en
Open access: closed
Locations: Medical Care (publishedVersion)
PubMed (publishedVersion)
Funders: Canadian Institutes of Health Research
Topics: Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords: health-related quality of life, clinical conditions, aphasia, cancer, Alzheimer's disease, balance disorders
MeSH terms: Aged, Aged, 80 and over, Disease, Female, Health Status Indicators, Hospitals, Humans, Long-Term Care, Male, Middle Aged, Ontario, Quality of Life, Residential Facilities, Databases as Topic, Patient Preference

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The Relationship of 60 Disease Diagnoses and 15 Conditions to Preference-Based Health-Related Quality of Life in Ontario Hospital-Based Long-Term Care Residents

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