The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Human C-reactive protein and the metabolic syndrome
Open accessAbstract
PURPOSE OF REVIEW: Low-grade inflammation is characteristic of the metabolic syndrome (MetS). C-reactive protein (CRP), the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. The purpose of this review is to outline the role of inflammation and high sensitivity CRP in the MetS. RECENT FINDINGS: Emerging laboratory and epidemiological data now link inflammation and high sensitivity CRP to insulin resistance and adiposity and other features of MetS. Furthermore, in large prospective studies, increased high sensitivity CRP levels in MetS confer greater cardiovascular risk. CRP has been shown to impair insulin signaling and contributes to atherothrombosis. SUMMARY: Thus, although a high CRP level predisposes to increased cardiovascular risk in MetS, future investigation is warranted on the in-vivo role of CRP in mediating vascular effects and resulting in increased cardiovascular events in MetS patients.
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Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
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THE INSULIN RESISTANCE SYNDROME: Definition and Dietary Approaches to Treatment
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The effect of including C-reactive protein in cardiovascular risk prediction models for women
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Cited by
Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training
Roberts, C. K., Hevener, A. L., & Barnard, R. J. (2013) · Comprehensive Physiology · doi:10.1002/cphy.c110062 · Cited by 831
Nutrients and Oxidative Stress: Friend or Foe?
Tan, B. L., Norhaizan, M. E., & Liew, W.-P.-P. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/9719584 · Cited by 403
Mozaffarian, D., Cao, H., King, I. B., Lemaitre, R. N., Song, X., Siscovick, D. S., & Hotamisligil, G. S. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-153-12-201012210-00005 · Cited by 363
Metabolic syndrome is an inflammatory disorder: A conspiracy between adipose tissue and phagocytes
Reddy, P., Lent-Schochet, D., Ramakrishnan, N., McLaughlin, M., & Jialal, I. (2019) · Clinica Chimica Acta · doi:10.1016/j.cca.2019.06.019 · Cited by 297
Self-citationSchwingshackl, L., & Hoffmann, G. (2013) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2013.04.008 · Cited by 271
Metadata
- Authors
- Devaraj, S., Singh, U., & Jialal, I.
- Venue
- Current Opinion in Lipidology
- Published
- 2009-06
- Volume
- 20
- Issue
- 3
- Pages
- 182-189
- ISSN
- 0957-9672 (ISSN-L)
- OpenAlex
- W2100896781
- Cited by
- 292
- References
- 12
- FWCI
- 12.95
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
