VSL#3 Improves Symptoms in Children With Irritable Bowel Syndrome: A Multicenter, Randomized, Placebo‐Controlled, Double‐Blind, Crossover Study

Guandalini, Stefano; Magazzù, Giuseppe; Chiaro, Andrea; La Balestra, Valeria; Di Nardo, Giovanni; Gopalan, Sarath; Sibal, A; Romano, Claudio; Canani, Roberto Berni; Lionetti, Paolo; Setty, Mala

doi:10.1097/mpg.0b013e3181ca4d95

VSL#3 Improves Symptoms in Children With Irritable Bowel Syndrome: A Multicenter, Randomized, Placebo‐Controlled, Double‐Blind, Crossover Study

Background and Objectives: Irritable bowel syndrome (IBS) is a common problem in pediatrics, for which no safe and effective treatment is available. Probiotics have shown some promising results in adult studies, but no positive study has been published on pediatric age. We aimed at investigating …