Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort
Open accessAbstract
Chronic transfusion therapy has played a central role in extending life expectancy for patients with hemoglobinopathies such as thalassemia. However, this life-saving therapy is associated with numerous complications that now comprise the bulk of management considerations for patients with thalassemia. This review reports on the experience of the Thalassemia Longitudinal Cohort and reviews available literature to establish guidelines for the management of patients with thalassemia.
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Risks of serious complications from transfusion-related iron toxicity and viral infections persist despite improvements in care.
“The risks of serious complications from transfusion-related iron toxicity and viral infections persist despite improvements in care.10,11”
From Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia (2018) · cites this paper as [10]
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Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia
Thompson, A. A., Walters, M. C., Kwiatkowski, J., Rasko, J. E. J., Ribeil, J.-A., Hongeng, S., Magrin, E., Schiller, G. J., Payen, E., Semeraro, M., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1705342 · Cited by 684 · see citing works
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- Authors
- Tubman, V. N., Fung, E. B., Vogiatzi, M., Thompson, A. A., Rogers, Z. R., Neufeld, E. J., & Kwiatkowski, J. L.
- Affiliations
- Boston Children's Hospital (US)
- Weill Cornell Medicine (US)
- Lurie Children's Hospital (US)
- The University of Texas Southwestern Medical Center (US)
- Children's Hospital of Philadelphia (US)
- Corresponding author
- Tubman, Venée N.
- Neufeld, Ellis J.
- ORCID
- Venue
- Journal of Pediatric Hematology/Oncology
- Published
- 2015-04
- Volume
- 37
- Issue
- 3
- Pages
- e162-e169
- ISSN
- 1077-4114 (ISSN-L)
- PMC
- PMC4511957
- OpenAlex
- W2317789348
- Cited by
- 68
- References
- 68
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 8 · 2022: 10 · 2021: 12 · 2020: 9 · 2019: 5 · 2018: 8 · 2017: 1 · 2016: 6
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Pediatric Hematology/Oncology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR002384)
- National Heart, Lung, and Blood Institute (U01-HL-65244, U01-HL72291, U01-HL-65238, U01-HL65233, U01HL065232, U01HL072291, U01-HL-65239, U01-HL65232, U01HL065244, U01HL065238, U01HL065233, U01HL065239, T32HL007574)
- National Center for Research Resources (UL1RR024131, ULI-RR024131, UL1RR025758, UL1RR024134, UL1RR024996)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Genetics › Hemoglobinopathies and Related Disorders
- Health Sciences › Medicine › Biochemistry › Blood transfusion and management
- Health Sciences › Medicine › Hematology › Blood groups and transfusion
- Keywords
- thalassemia, chronic transfusion, transfusion reactions, patient monitoring, hemoglobinopathies, longitudinal cohort, clinical management guidelines
- MeSH terms
- Blood Transfusion, Hemoglobinopathies, Humans, Longitudinal Studies, Monitoring, Physiologic, Thalassemia
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