Shunt Lesions Part I: Patent Ductus Arteriosus, Atrial Septal Defect, Ventricular Septal Defect, and Atrioventricular Septal Defect
Abstract
OBJECTIVES: This review summarizes the current understanding of the pathophysiology and perioperative management of patent ductus arteriosus, atrial septal defect, ventricular septal defect, and atrioventricular septal defect. DATA SOURCE: MEDLINE and PubMed. CONCLUSIONS: The four congenital cardiac lesions that are the subject of this review, patent ductus arteriosus, atrial septal defect, ventricular septal defect, and atrioventricular septal defect, are the most commonly found defects causing a left-to-right shunt. These defects frequently warrant transcatheter or surgical intervention. Although the perioperative care is relatively straightforward for many of these patients, there are a number of management strategies and complications associated with each intervention. The treatment outcomes for all of these lesions are very good in the current era.
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The top seven congenital heart diseases include ventricular septal defect, atrial septal defect, atrioventricular septal defect, Ebstein's anomaly, tetralogy of Fallot, transposition of great arteries, and hypoplastic left heart syndrome.
“The top seven CHDs include ventricular septal defect (VSD), atrial septal defect (ASD), atrioventricular septal defect (AVSD), Ebstein’s anomaly (EA), tetralogy of Fallot (TOF), transposition of great arteries (TGA), and hypoplastic left heart syndrome (HLHS) [3,4].”
From Deep Learning for Improving the Effectiveness of Routine Prenatal Screening for Major Congenital Heart Diseases (2022) · cites this paper as [4]
Cites
Application of a mechanical heart and lung apparatus to cardiac surgery.
(1954) · Cited by 1,028 · see citing works
Patent Ductus Arteriosus of the Preterm Infant
Hamrick, S. E. G., & Hansmann, G. (2010) · PEDIATRICS · doi:10.1542/peds.2009-3506 · Cited by 543 · see citing works
Amin, Z., Hijazi, Z. M., Bass, J. L., Cheatham, J. P., Hellenbrand, W. E., & Kleinman, C. S. (2004) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.20211 · Cited by 527 · see citing works
SURGICAL LIGATION OF A PATENT DUCTUS ARTERIOSUS
Gross, R. E., & Hubbard, J. P. (1939) · JAMA · doi:10.1001/jama.1939.02800080049011 · Cited by 506 · see citing works
Surgical Ligation of a Patent Ductus Arteriosus
Gross, R. E. (1984) · JAMA · doi:10.1001/jama.1984.03340330059026 · Cited by 494 · see citing works
Lewis, F. J., & Taufic, M. (1953) · PubMed · Cited by 468 · see citing works
A Comparison of Ibuprofen and Indomethacin for Closure of Patent Ductus Arteriosus
Overmeire, B. V., Smets, K., Lecoutere, D., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200009073431001 · Cited by 453 · see citing works
Graham, T. P. (2006) · Yearbook of Cardiology · doi:10.1016/s0145-4145(07)70085-0 · Cited by 404 · see citing works
Multicenter USA Amplatzer Patent Ductus Arteriosus Occlusion Device Trial
Pass, R. H., Hijazi, Z. M., Hsu, D. T., et al. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.03.074 · Cited by 345 · see citing works
Ohlsson, A., Walia, R., & Shah, S. S. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003481.pub6 · Cited by 334 · see citing works
Lillehei, C. W., COHEN, M., Warden, H. E., & Varco, R. L. (1955) · PubMed · Cited by 290 · see citing works
Walsh, E. P., Saul, J. P., Sholler, G. F., Triedman, J. K., Jonas, R. A., Mayer, J. E., & WESSEL, D. L. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00040-5 · Cited by 220 · see citing works
Jones, T. K., Latson, L., Zahn, E. M., Fleishman, C. E., Jacobson, J. L., Vincent, R. N., & Kanter, K. R. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.11.053 · Cited by 179 · see citing works
Intravenous Amiodarone for Incessant Tachyarrhythmias in Children
Saul, J. P., Scott, W. A., Brown, S., Marantz, P. M., Acevedo, V. S., Etheridge, S. P., Perry, J. C., Triedman, J. K., Burriss, S. W., Cargo, P., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.534149 · Cited by 176 · see citing works
BACHA, E. A., Cao, Q., Starr, J. P., et al. (2003) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(03)01043-2 · Cited by 168 · see citing works
Transcatheter Device Closure of Congenital and Postoperative Residual Ventricular Septal Defects
Knauth, A. L., Lock, J. E., Perry, S. B., et al. (2004) · Circulation · doi:10.1161/01.cir.0000137116.12176.a6 · Cited by 168 · see citing works
PDA Ligation and Health Outcomes: A Meta-analysis
Weisz, D. E., More, K., McNamara, P. J., et al. (2014) · PEDIATRICS · doi:10.1542/peds.2013-3431 · Cited by 158 · see citing works
Fourty-Six Years of Patent Ductus Arteriosus Division at Childrenʼs Memoreal Hospital of Chicago
&NA; (1994) · Annals of Surgery · doi:10.1097/00000658-199409000-00016 · Cited by 147 · see citing works
Stewart, R. D., Bailliard, F., Kelle, A. M., Backer, C. L., Young, L., & Mavroudis, C. D. (2007) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2007.04.130 · Cited by 147 · see citing works
Self-citationMcNamara, P. J., Stewart, L., Shivananda, S. P., et al. (2010) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2010.01.011 · Cited by 140 · see citing works
Restrictive ventricular septal defect: How small is too small to close?
Backer, C. L., Winters, R. C., Zales, V. R., et al. (1993) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(95)90006-3 · Cited by 105 · see citing works
Self-citationProgress in Late Results Among Pediatric Cardiac Surgery Patients
Raissadati, A., Nieminen, H. P., Jokinen, E. V., & Sairanen, H. I. (2014) · Circulation · doi:10.1161/circulationaha.114.011190 · Cited by 104 · see citing works
Percutaneous Treatment of Patent Foramen Ovale and Atrial Septal Defects
Tobis, J. M., & Shenoda, M. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.01.086 · Cited by 98 · see citing works
Need for closure of secundum atrial septal defect in infancy
Lammers, A. E., Hager, A., Eicken, A., et al. (2005) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2004.10.007 · Cited by 92 · see citing works
Backer, C. L., Stewart, R. D., Bailliard, F., et al. (2007) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2007.04.129 · Cited by 90 · see citing works
Self-citationThe diagnostic features of atrioventricular septal defect with common atrioventricular junction
Anderson, R. H., Ho, S. Y., Falcão, S. D. R., et al. (1998) · Cardiology in the Young · doi:10.1017/s1047951100004613 · Cited by 78 · see citing works
Jacobs, J. P., Giroud, J. M., Quintessenza, J. A., et al. (2003) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(03)01035-x · Cited by 54 · see citing works
Device Closure of Secundum Atrial Septal Defects in Children <15 kg
Bartakian, S., Fagan, T. E., Schaffer, M. S., et al. (2012) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2012.07.009 · Cited by 46 · see citing works
Transcatheter Closure of Large Atrial Septal Defects
Baruteau, A., Petit, J., Lambert, V., Gouton, M., Piot, D., Brénot, P., Angel, C.-Y., Houyel, L., Bret, E. L., Roussin, R., et al. (2014) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.113.001254 · Cited by 44 · see citing works
Recovery of vocal fold immobility following isolated patent ductus arteriosus ligation
Nichols, B. G., Jabbour, J., Hehir, D. A., et al. (2014) · International Journal of Pediatric Otorhinolaryngology · doi:10.1016/j.ijporl.2014.05.019 · Cited by 42 · see citing works
Assessment of Vocal Fold Mobility Before and After Cardiothoracic Surgery in Children
Carpes, L. F., Kozak, F. K., LeBlanc, J. G., et al. (2011) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archoto.2011.84 · Cited by 42 · see citing works
Anderson, R. H., Henry, G. W., & Nuttall, G. L. (1998) · Cardiology in the Young · doi:10.1017/s1047951100004583 · Cited by 33 · see citing works
Coronary artery perfusion and myocardial performance after patent ductus arteriosus ligation
Sehgal, A., & McNamara, P. J. (2011) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2011.10.035 · Cited by 32 · see citing works
Devlin, P. J., Russell, H. M., Mongé, M. C., et al. (2014) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2014.01.059 · Cited by 28 · see citing works
Self-citationCardiac Tamponade Complicating Postpericardiotomy Syndrome
Scarfone, R. J., Donoghue, A. J., & Alessandrini, E. A. (2003) · Pediatric Emergency Care · doi:10.1097/01.pec.0000092573.40174.74 · Cited by 16 · see citing works
Advanced pulmonary vascular disease: the Eisenmenger syndrome
Kumar, R., & Sandoval, J. (2009) · Cardiology in the Young · doi:10.1017/s1047951109990783 · Cited by 15 · see citing works
Pathophysiology of acute pulmonary vasoconstriction
Kulik, T. J. (2010) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0b013e3181c766c6 · Cited by 8 · see citing works
Öç, M., Farsak, B., Öç, B., et al. (2012) · The Heart Surgery Forum · doi:10.1532/hsf98.20121069 · Cited by 1 · see citing works
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Nurmaini, S., Partan, R. U., Bernolian, N., Sapitri, A. I., Tutuko, B., Rachmatullah, M. N., Darmawahyuni, A., Firdaus, F., & Mose, J. C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11216454 · Cited by 61 · see citing works
- Authors
- Backer, C. L., Eltayeb, O., Mongé, M. C., Mazwi, M. L., & Costello, J. M.
- Affiliations
- Northwestern University (US)
- Venue
- Pediatric Critical Care Medicine
- Published
- 2016-08
- Volume
- 17
- Issue
- 8
- Pages
- S302-S309
- ISSN
- 1529-7535 (ISSN-L)
- OpenAlex
- W2512839304
- Cited by
- 13
- References
- 38
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 3 · 2018: 1 · 2017: 1
- FWCI
- 0.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatric Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiovascular Conditions and Treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
- Keywords
- patent ductus arteriosus, atrial septal defect, ventricular septal defect, atrioventricular septal defect, left-to-right shunt, congenital heart disease, pathophysiology, perioperative care, transcatheter interventions, surgical treatment
- MeSH terms
- Child, Child, Preschool, Ductus Arteriosus, Patent, Heart Septal Defects, Heart Septal Defects, Atrial, Heart Septal Defects, Ventricular, Cardiac Surgical Procedures, Humans, Infant, Infant, Newborn, Treatment Outcome, Perioperative Care
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