Genital and extragenital gonorrhea and chlamydia in children and adolescents evaluated for sexual abuse.
Abstract
OBJECTIVE: The aim of this study was to describe the use of a nucleic acid amplification test in detecting genital and extragenital Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) in children and adolescents assessed for sexual abuse/assault. METHODS: The charts of children aged 0 to 17 years, consecutively evaluated for sexual victimization, in emergency department and outpatient settings were reviewed. Data extracted included age, sex, type of sexual contact, anogenital findings, previous sexual contact, toxicology results, and sites tested for NG and CT. RESULTS: Of the 1319 patients who were tested, 579 were tested at more than 1 site, and 120 had at least 1 infected site. Chlamydia trachomatis was identified in 104 patients, and NG was found in 33. In bivariate analysis, a positive test was associated with female sex, age older than 11 years, previous sexual contact, acute or healed genital injury, drug/alcohol intoxication, and examination within 72 hours of sexual contact. Fifty-one patients had positive anal tests, and 24 had positive oral tests. More than 75% of patients with positive extragenital tests had additional positive tests or anogenital injury. Most with a positive anal (59%) or oral (77%) test did not report that the assailant's genitals came into contact with that site. CONCLUSIONS: Positive tests for NG and CT in patients evaluated for sexual victimization may represent infection from sexual contact, contiguous spread of infection, or the presence of infected assailant secretions. Relying on patient reports of symptoms, or types of sexual contact, to determine need for testing may miss NG and CT infections in patients evaluated for sexual victimization.
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History and reported type of sexual contact might not be a reliable indicator.
“History and reported type of sexual contact might not be a reliable indicator, and urogenital, pharyngeal, and rectal testing should be considered for preverbal children and children who cannot verbalize details of the assault (1438,1449).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1449]
Cites
Sexually Transmitted Diseases Treatment Guidelines, 2006
SKOLNIK, N. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-313-4_17 · Cited by 3,129 · see citing works
Papp, J. R., Schachter, J., Gaydos, C. A., & Pol, B. J. V. D. (2014) · Europe PMC (PubMed Central) · Cited by 593 · see citing works
The evaluation of children in the primary care setting when sexual abuse is suspected.
Jenny, C., Crawford-Jakubiak, J. E., COMMITTEE ON CHILD ABUSE AND NEGLECT, Jenny, C., Crawford-Jakubiak, J. E., Christian, C. W., Crawford-Jakubiak, J. E., Flaherty, E. G., Leventhal, J. M., Lukefahr, J. L., et al. (2013) · PEDIATRICS · doi:10.1542/peds.2013-1741 · Cited by 222 · see citing works
Self-citationNucleic Acid Amplification Testing for Neisseria gonorrhoeae
Whiley, D. M., TAPSALL, J. W., & Sloots, T. P. (2006) · Journal of Molecular Diagnostics · doi:10.2353/jmoldx.2006.050045 · Cited by 192 · see citing works
Bachmann, L. H., Johnson, R. E., Cheng, H. M., Markowitz, L. E., Papp, J. R., Palella, F. J., & Hook, E. W. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02398-09 · Cited by 170 · see citing works
Tabrizi, S. N., Unemo, M., Limnios, A. E., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.01217-11 · Cited by 146 · see citing works
Nucleic Acid Amplification Tests for Diagnosis of Neisseria gonorrhoeae Oropharyngeal Infections
Bachmann, L. H., Johnson, R. E., Cheng, H. M., et al. (2009) · Journal of Clinical Microbiology · doi:10.1128/jcm.01581-08 · Cited by 138 · see citing works
Epidemiology of Sexually Transmitted Infections in Suspected Child Victims of Sexual Assault
Girardet, R. G., Lahoti, S. L., Howard, L. A., Fajman, N. N., Sawyer, M. K., Driebe, E. M., Lee, F. L. F., Sautter, R. L., Greenwald, E. F., Beck‐Sagué, C. M., et al. (2009) · PEDIATRICS · doi:10.1542/peds.2008-2947 · Cited by 129 · see citing works
Siegel, R. M., Schubert, C. J., Myers, P. A., et al. (1995) · PEDIATRICS · doi:10.1542/peds.96.6.1090 · Cited by 103 · see citing works
Black, C. M., Driebe, E. M., Howard, L. A., Fajman, N. N., Sawyer, M. K., Girardet, R. G., Sautter, R. L., Greenwald, E. F., Beck‐Sagué, C. M., Unger, E. R., et al. (2009) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e31819b592e · Cited by 99 · see citing works
Schachter, J., Chow, J. M., Howard, H., et al. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.02620-05 · Cited by 82 · see citing works
Peters, R. P. H., Nijsten, N., Mutsaers, J. A. E. M., Jansen, C. L., Morré, S. A., & van Leeuwen, A. P. (2011) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e31821890e9 · Cited by 76 · see citing works
Use of Nucleic Acid Amplification Testing for Diagnosis of Anorectal Sexually Transmitted Infections
Cosentino, L. A., Campbell, T. E., Jett, A., Macio, I. S., Zamborsky, T., Cranston, R., & Hillier, S. L. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.00185-12 · Cited by 71 · see citing works
Forensic Evidence Collection and DNA Identification in Acute Child Sexual Assault
Thackeray, J. D., Hornor, G., Benzinger, E., et al. (2011) · PEDIATRICS · doi:10.1542/peds.2010-3498 · Cited by 71 · see citing works
Collection of Forensic Evidence From Pediatric Victims of Sexual Assault
Girardet, R. G., Bolton, K. L., Lahoti, S. L., et al. (2011) · PEDIATRICS · doi:10.1542/peds.2010-3037 · Cited by 63 · see citing works
Postema, E. J., Remeijer, L., & van der Meijden, W. I. (1996) · Sexually Transmitted Infections · doi:10.1136/sti.72.3.203 · Cited by 48 · see citing works
Kellogg, N. D., Baillargeon, J., Lukefahr, J. L., et al. (2004) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2004.07.006 · Cited by 42 · see citing works
Self-citationMoncada, J., Donegan, E. A., & Schachter, J. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.02301-07 · Cited by 41 · see citing works
Chlamydia trachomatisconjunctivitis: Prevalence and association with genital tract infection
Garland, S. M., Tabrizi, S. N., Lees, M. I., et al. (1995) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1995.tb139939.x · Cited by 41 · see citing works
Sexual Assault and Abuse of Children
Hammerschlag, M. R. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir700 · Cited by 40 · see citing works
Early‐onset neonatal group B streptococcal sepsis: economics of various prevention strategies
Garland, S. M., & Kelly, N. (1995) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1995.tb139969.x · Cited by 40 · see citing works
Meader, E. J., Waters, J., & Sillis, M. (2007) · Sexually Transmitted Infections · doi:10.1136/sti.2007.027862 · Cited by 28 · see citing works
Sexually transmitted diseases in sexually abused girls and adolescents
Shapiro, R. A., & Makoroff, K. L. (2006) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/01.gco.0000242950.09997.ca · Cited by 26 · see citing works
Genital Infection with Chlamydia trachomatis in Patients with Chlamydial Conjunctivitis
Stenberg, K., & Mårdh, P. A. (1991) · Sexually Transmitted Diseases · doi:10.1097/00007435-199101000-00001 · Cited by 26 · see citing works
What's in a Name? — Medical Samples and Scientific Evidence in Sexual Assaults
Keating, S. M., & Allard, J. E. (1994) · Medicine Science and the Law · doi:10.1177/002580249403400302 · Cited by 26 · see citing works
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Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Interpretation of medical findings in suspected child sexual abuse: an update for 2018.
Adams, J. A., Farst, K. J., & Kellogg, N. D. (2018) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2017.12.011 · Cited by 163 · see citing works
Self-citation
- Authors
- Kellogg, N. D., Melville, J. D., Lukefahr, J. L., Nienow, S. M., & Russell, E. L.
- Affiliations
- The University of Texas at San Antonio Health Science Center (US)
- Medical University of South Carolina (US)
- University of New Mexico (US)
- Children's Hospital of San Antonio (US)
- Corresponding author
- Kellogg, Nancy D.
- Lukefahr, James L.
- Venue
- Pediatric Emergency Care
- Published
- 2018-11
- Volume
- 34
- Issue
- 11
- Pages
- 761-766
- ISSN
- 0749-5161 (ISSN-L)
- 1535-1815
- OpenAlex
- W2567722763
- Cited by
- 34
- References
- 25
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 3 · 2023: 5 · 2022: 1 · 2021: 6 · 2020: 4 · 2019: 4 · 2018: 1 · 2017: 2
- FWCI
- 2.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatric Emergency Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Health Professions › General Health Professions › Adolescent Sexual and Reproductive Health
- Social Sciences › Gender Studies › Sexual Assault and Victimization Studies
- Keywords
- gonorrhea, chlamydia, Neisseria gonorrhoeae, Chlamydia trachomatis, sexual abuse, child sexual assault, children and adolescents, extragenital infection, anal infection, oral infection, nucleic acid amplification tests, anogenital injuries
- MeSH terms
- Adolescent, Child, Child, Preschool, Chlamydia Infections, Chlamydia trachomatis, Female, Gonorrhea, Humans, Infant, Male, Neisseria gonorrhoeae, Retrospective Studies, Risk Factors, Sexual Behavior, Sex Offenses, Crime Victims, Nucleic Acid Amplification Techniques
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