The Chimera of Low Back Pain Etiology: A Clinical Rehabilitation Perspective
Abstract
From the Physical and Rehabilitation Medicine, University of Brescia, Brescia, Italy (SN); IRCCS Don Gnocchi Foundation, Italy (SN); and ISICO (Italian Scientific Spine Institute), Milan, Italy (FZ). All correspondence and requests for reprints should be addressed to: Stefano Negrini, MD, Physical and Rehabilitation Medicine, Department of Clinical Experimental Sciences, University of Brescia, Viale Europa 11, 25123 Brescia, Italy. Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article. This commentary is being published in cooperation with the European Journal of Physical and Rehabilitation Medicine as part of a collaborative project that started in 2008.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Chronic low back pain is often non-specific and may arise from multiple biologic and behavioral causes that differ across individuals.
“Such cLBP is often termed non-specific, and may be due to multiple biologic and behavioral etiologies.”
From Report of the NIH Task Force on research standards for chronic low back pain. (2014) · cites this paper as [87]
Cites
1987 Volvo Award in Clinical Sciences: A New Clinical Model for the Treatment of Low-Back Pain
Waddell, G. (1987) · Spine · doi:10.1097/00007632-198709000-00002 · Cited by 1,244 · see citing works
Lumbar Degenerative Disk Disease
Modic, M. T., & Ross, J. S. (2007) · Radiology · doi:10.1148/radiol.2451051706 · Cited by 505 · see citing works
Pain genetics: past, present and future
Mogil, J. S. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.02.004 · Cited by 318 · see citing works
Genetic factors in pain and its treatment
Stamer, U. M., & Stüber, F. (2007) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0b013e3282ef6b2c · Cited by 159 · see citing works
Genetics of chronic pain states
Buskila, D. (2007) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2007.02.011 · Cited by 109 · see citing works
Muralidharan, A., & Smith, M. T. (2011) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.2011.01340.x · Cited by 52 · see citing works
Intervertebral disc biomechanical analysis using the finite element modeling based on medical images
Li, H., & Wang, Z. (2006) · Computerized Medical Imaging and Graphics · doi:10.1016/j.compmedimag.2006.09.004 · Cited by 50 · see citing works
Gene therapy for disc degeneration
Vadalà, G., Sowa, G., & Kang, J. D. (2007) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.7.2.185 · Cited by 37 · see citing works
Massé‐Alarie, H., & Schneider, C. (2011) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2011.03.004 · Cited by 14 · see citing works
Evidence (and research) are the only possible basis of medicine
Négrini, S. (2011) · Rehabilitación · doi:10.1016/j.rh.2011.05.008 · Cited by 7 · see citing works
Négrini, S. (2006) · PubMed · Cited by 6 · see citing works
PubMed in progress: latest changes in MeSH and MyNCBI.
Giglia, E. (2011) · PubMed · Cited by 4 · see citing works
PubMed in progress: further changes in the redesigned interface.
Giglia, E., & Spinelli, O. M. (2010) · PubMed · Cited by 4 · see citing works
Zaina, F., & Négrini, S. (2012) · PubMed · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Report of the NIH Task Force on research standards for chronic low back pain.
Deyo, R. A., Dworkin, S. F., Amtmann, D., Andersson, G., Borenstein, D., Carragee, E., Carrino, J., Chou, R., Cook, K., DeLitto, A., et al. (2014) · The Journal of Pain · doi:10.1016/j.jpain.2014.03.005 · Cited by 533 · see citing works
- Authors
- Negrini, S., & Zaina, F.
- Affiliations
- Istituto Scientifico Italiano Colonna Vertebrale (IT)
- ORCID
- Zaina, Fabio
- Venue
- American Journal of Physical Medicine & Rehabilitation
- Published
- 2013-01
- Volume
- 92
- Issue
- 1
- Pages
- 93-97
- ISSN
- 0894-9115 (ISSN-L)
- OpenAlex
- W2030772257
- Cited by
- 33
- References
- 14
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 3 · 2019: 2 · 2018: 2 · 2016: 2 · 2015: 3 · 2014: 10
- FWCI
- 3.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physical Medicine & Rehabilitation (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- low back pain, etiology, spinal pain
- MeSH terms
- Adaptation, Psychological, Humans, Physical and Rehabilitation Medicine, Low Back Pain, Evidence-Based Medicine, Genetic Predisposition to Disease, Epigenesis, Genetic, Intervertebral Disc Degeneration, Pain Perception
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
