The DOI matches its Crossref record; 53 of the 54 references it cites were found in a registry or an index.
The opioid epidemic and national guidelines for opioid therapy for chronic noncancer pain: a perspective from different continents
Open accessAbstract
Introduction: A marked rise in opioid prescriptions for patients with chronic noncancer pain (CNCP) with a parallel increase in opioid abuse/misuse, and resulting deaths was noted in the Unites states in the past decade (opioid epidemic). In response, the US Center of Diseases Control (CDC) developed a guideline for prescribing of opioids for patients with CNCP. Objectives: To assess (1) if there is an opioid epidemic in Australia, Canada, and Germany (2) to compare Australian, Canadian, German, and Center of Diseases Control guidelines recommendations for long-term opioid therapy for CNCP. Methods: National evidence-based guidelines and PubMed were searched for recommendations for opioid prescriptions for CNCP. Results: There are signs of an opioid epidemic in Australia and Canada, but not in Germany. Guidelines in all 4 countries provide similar recommendations: opioids are not the first-line therapy for patients with CNCP; regular clinical assessments of benefits and harms are necessary; excessive doses should be avoided (recommended morphine equivalent daily doses range from 50 to 200 mg/d); stopping rules should be followed. All guidelines do not recommend the use of opioids in chronic pain conditions without an established nociceptive or neuropathic cause such as fibromyalgia and primary headache. Conclusion: Implementation of opioid prescribing guidelines should ensure that physicians prescribe opioids only for appropriate indications in limited doses for selected patients and advice patients on their safe use. These measures could contribute to reduce prescription opioid misuse/abuse and deaths.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70251-0 · Cited by 3,980
AGREE II: advancing guideline development, reporting and evaluation in health care
Brouwers, M. C., Kho, M. E., Browman, G. P., Burgers, J. S., Cluzeau, F., Feder, G., Fervers, B., Graham, I. D., Grimshaw, J., Hanna, S. E., et al. (2010) · Canadian Medical Association Journal · doi:10.1503/cmaj.090449 · Cited by 3,790
Hochberg, M. C., Altman, R. D., April, K. T., Benkhalti, M., Guyatt, G., McGowan, J., Towheed, T., Welch, V., Wells, G., & Tugwell, P. (2012) · Arthritis Care & Research · doi:10.1002/acr.21596 · Cited by 3,068
CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016
Dowell, D., Haegerich, T. M., & Chou, R. (2016) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6501e1 · Cited by 2,697
Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain
Chou, R., Fanciullo, G. J., Fine, P. G., Adler, J. A., Ballantyne, J. C., Davies, P., Donovan, M. I., Fishbain, D. A., Foley, K. M., Fudin, J., et al. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2008.10.008 · Cited by 2,192
Shea, B. J., Hamel, C., Wells, G. A., Bouter, L. M., Kristjansson, E., Grimshaw, J., Henry, D. A., & Boers, M. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.10.009 · Cited by 1,755
Opioid Prescriptions for Chronic Pain and Overdose
Dunn, K. M., Saunders, K. W., Rutter, C. M., Banta‐Green, C. J., Merrill, J. O., Sullivan, M. D., Weisner, C. M., Silverberg, M. J., Campbell, C. I., Psaty, B. M., et al. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-152-2-201001190-00006 · Cited by 1,265
Opioid Epidemic in the United States
Manchikanti, L. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/es9 · Cited by 1,180
Trends in Opioid Analgesic Abuse and Mortality in the United States
Dart, R. C., Surratt, H. L., Cicero, T. J., Parrino, M. W., Severtson, S. G., Bucher‐Bartelson, B., & Green, J. L. (2015) · New England Journal of Medicine · doi:10.1056/nejmsa1406143 · Cited by 1,140
Barriers and Strategies in Guideline Implementation—A Scoping Review
Fischer, F., Lange, K., Klose, K., Greiner, W., & Kraemer, A. (2016) · Healthcare · doi:10.3390/healthcare4030036 · Cited by 960
Research works printed but not linked: 3
- 2012, UAW-News International Die unkritische Anwendung von Fentanylpflastern erhöht das Risiko für schwerwiegende Nebenwirkungen (The uncritical use of fentanyl patches increases the risk of serious adverse events, Dtsch Ärztebl, 109, A724
- Brennan, 2004, Pain relief as a human right, Pain Clinical Updates, 12, 1
- Müller-Schwefe, 1998, Aktionsprogramm Schmerz, Z Angew Schmerzth, 4, 1
Cited by
Sorted by citations
Opioids for Chronic Noncancer Pain
Busse, J. W., Wang, L., Kamaleldin, M., Craigie, S., Riva, J. J., Montoya, L., Mulla, S. M., Lopes, L. C., Vogel, N., Chen, E., et al. (2018) · JAMA · doi:10.1001/jama.2018.18472 · Cited by 766
Recent trends in life expectancy across high income countries: retrospective observational study
Ho, J. Y., & Hendi, A. S. (2018) · BMJ · doi:10.1136/bmj.k2562 · Cited by 439
Häuser, W., Finn, D. P., Kalso, E. A., Krcevski‐Škvarč, N., Kress, H. G., Morlion, B. J., Perrot, S., Schäfer, M., Wells, C., & Brill, S. (2018) · European Journal of Pain · doi:10.1002/ejp.1297 · Cited by 211
Self-citationBacteriophage interactions with mammalian tissue: Therapeutic applications
Huh, H., Wong, S. L., Jean, J. S., & Slavcev, R. A. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.003 · Cited by 190
The Modified WHO Analgesic Ladder: Is It Appropriate for Chronic Non-Cancer Pain?
Yang, J., Bauer, B. A., Wahner‐Roedler, D. L., Chon, T. Y., & Xiao, L. (2020) · Journal of Pain Research · doi:10.2147/jpr.s244173 · Cited by 192
Metadata
- Authors
- Häuser, W., Schug, S., & Furlan, A. D.
- Affiliations
- Klinikum Saarbrücken (DE)
- The University of Western Australia (AU)
- University of Toronto (CA)
- Corresponding author
- Häuser, Winfried
- Venue
- PAIN Reports
- Published
- 2017-05
- Volume
- 2
- Issue
- 3
- Pages
- e599
- ISSN
- 2471-2531 (ISSN-L)
- PMC
- PMC5741305
- OpenAlex
- W2613863269
- Cited by
- 154
- References
- 54
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 11 · 2023: 4 · 2022: 19 · 2021: 22 · 2020: 26 · 2019: 26 · 2018: 30 · 2017: 4
- FWCI
- 22.08
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PAIN Reports (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Pfizer
- Seqirus
- Pfizer Pharmaceuticals
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Keywords
- opioid epidemic, chronic non-cancer pain, opioid prescribing guidelines, opioid misuse, opioid abuse, opioid-related deaths, CDC opioid prescribing guidelines, morphine equivalent daily dose, fibromyalgia, primary headache, Australia, Canada, Germany
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
