The DOI matches its Crossref record; 58 of the 59 references it cites were found in a registry or an index.
A peer-education intervention to reduce injection risk behaviors for HIV and hepatitis C virus infection in young injection drug users
Abstract
OBJECTIVES: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (IDU). DESIGN: We conducted a randomized controlled trial involving HIV and HCV antibody-negative IDU, aged 15-30 years, recruited in five United States cities. A six-session, small-group, cognitive behavioral, skills-building intervention in which participants were taught peer education skills (n = 431) was compared with a time-equivalent attention control (n = 423). Baseline visits included interviews for sociodemographic, psychosocial, and behavioral factors during the previous 3 months; HIV and HCV antibody testing; and pre/posttest counselling. Procedures were repeated 3 and 6 months postintervention. RESULTS: The intervention produced a 29% greater decline in overall injection risk 6 months postintervention relative to the control [proportional odds ratio 0.71; 95% confidence limit (CL) 0.52, 0.97], and a 76% decrease compared with baseline. Decreases were also observed for sexual risk behaviors, but they did not differ by trial arm. Overall HCV infection incidence (18.4/100 person-years) did not differ significantly across trial arms (relative risk 1.15; 95% CL 0.72, 1.82). No HIV seroconversions were observed. CONCLUSION: Interventions providing information, enhancing risk-reduction skills, and motivating behavior change through peer education training can reduce injection risk behaviors, although risk elimination might be necessary to prevent HCV transmission.
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“These RDS interventions have been shown to be quite effective at reducing risk behavior [62].”
From Social Network Analysis for Program Implementation (2015) · cites this paper as [62]
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“behavior change interventions based on cognitive– behavioral skills-building [34] andpeer-based interventions [35] have been evaluated, those studies included non-IDU or IDU who were not recent initiates.”
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Metadata
- Authors
- Garfein, R. S., Golub, E. T., Greenberg, A. E., Hagan, H., Hanson, D. L., Hudson, S. M., Kapadia, F., Latka, M. H., Ouellet, L. J., Purcell, D. W., Strathdee, S. A., & Thiede, H.
- Affiliations
- Centers for Disease Control and Prevention (US)
- Johns Hopkins University (US)
- National Development and Research Institutes (US)
- New York Academy of Medicine (US)
- University of Illinois Chicago (US)
- University of California San Diego (US)
- Public Health – Seattle & King County (US)
- Corresponding author
- Garfein, Richard S
- ORCID
- Venue
- AIDS
- Published
- 2007-09
- Volume
- 21
- Issue
- 14
- Pages
- 1923-1932
- ISSN
- 0269-9370 (ISSN-L)
- OpenAlex
- W2065686470
- Cited by
- 159
- References
- 59
- Citations by year
- 2025: 2 · 2024: 6 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 11 · 2019: 4 · 2018: 7 · 2017: 9 · 2016: 4 · 2015: 7 · 2014: 10 · 2013: 12 · 2012: 13
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- AIDS (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (U64 CCU 017615, U64/CCU317662, U64/CCU217659, U64/CCU517656, U64/CCU917655)
- Topics
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- peer education, people who inject drugs, HIV prevention, hepatitis C virus, injection risk behavior, sexual risk behavior, cognitive-behavioral intervention, young adults, HCV transmission, HIV seroconversion
- MeSH terms
- Adolescent, Adolescent Behavior, Adult, Behavior Therapy, Female, Health Education, Hepatitis C, Humans, Male, Peer Group, Sexual Behavior, United States, HIV Infections, Substance Abuse, Intravenous, Incidence, Treatment Outcome, Risk Reduction Behavior
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