The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Mother-to-Child Transmission of HIV in Kenya: Results From a Nationally Representative Study
Open accessAbstract
BACKGROUND: Kenya has an estimated 13,000 new infant HIV infections that occur annually. We measured the burden of HIV infection among women of childbearing age and assessed access to and coverage of key prevention of mother-to-child transmission interventions. METHODS: The second Kenya AIDS Indicator Survey was a nationally representative 2-stage cluster sample of households. We analyzed data from women aged 15-54 years who had delivered a newborn within the preceding 5 years and from whom we obtained samples for HIV testing. RESULTS: Of 3310 women who had ≥1 live birth in the preceding 5 years, 2862 (86.5%) consented to HIV testing in the survey, and 171 (6.1%) were found to be infected. Ninety-five percent received prenatal care, 93.1% were screened for HIV during prenatal care, and of those screened, 97.8% received their test results. Seventy-six women were known to be infected in their last pregnancy. Of these, 54 (72.3%) received antepartum antiretroviral prophylaxis, and 51 (69.1%) received intrapartum prophylaxis; 56 (75.3%) reported their newborns received postpartum prophylaxis. Of the 76 children born to these mothers, 63 (82.5%) were tested for HIV at the first immunization visit or thereafter, and 8 (15.1%) were HIV infected. CONCLUSIONS: We found a substantial burden of HIV in Kenyan women of childbearing age and a cumulative 5-year mother-to-child transmission rate of 15%. Although screening has improved over the past 5 years, fewer than three-quarters of infected pregnant women are receiving antiretroviral prophylaxis. Universal antiretroviral therapy for HIV-infected pregnant women will be essential in achieving Kenyan's target to eliminate mother-to-child transmission to <5% by 2015.
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“the rates are several times higher in practice because of the high drop-out rates of HIV-positive women along the PMTCT care cascade [1-3,6-9].”
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Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61728-0 · Cited by 14,070
The Kenya AIDS Indicator Survey 2012
Waruiru, W., Kim, A. A., Kimanga, D. O., et al. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000114 · Cited by 132
Self-citationNyandiko, W. M., Otieno‐Nyunya, B., Musick, B. S., et al. (2010) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181d8ad51 · Cited by 70
The Status of HIV Testing and Counseling in Kenya
Ng’ang’a, A., Waruiru, W., Ngare, C. W., Ssempijja, V., Gachuki, T., Njoroge, I., Oluoch, P., Kimanga, D. O., Maina, W. K., Mpazanje, R., et al. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000102 · Cited by 65
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Kawakyu, N., Nduati, R., Munguambe, K., Coutinho, J., Mburu, N., DeCastro, G., Inguane, C., Zunt, A., Abburi, N., Sherr, K., et al. (2019) · JMIR mHealth and uHealth · doi:10.2196/13963 · Cited by 19
Metadata
- Authors
- Sirengo, M., Muthoni, L., Kellogg, T. A., A. Kim, A., Katana, A., Mwanyumba, S., Kimanga, D. O., Maina, W. K., Muraguri, N., Elly, B., & Rutherford, G. W.
- Affiliations
- Centers for Disease Control and Prevention (US)
- University of California, San Francisco (US)
- Ministry of Health (KE)
- Corresponding author
- Sirengo, Martin
- Kimanga, Davies O.
- Maina, William K.
- Muraguri, Nicolas
- Venue
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2014-05-01
- Volume
- 66
- Issue
- Supplement 1
- Pages
- S66-S74
- ISSN
- 1525-4135 (ISSN-L)
- PMC
- PMC4790087
- OpenAlex
- W2072622199
- Cited by
- 43
- References
- 4
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 5 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 4
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- JAIDS Journal of Acquired Immune Deficiency Syndromes (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (CC999999)
- Centers for Disease Control and Prevention (U19GH000069)
- National Institute of Mental Health (P30MH062246)
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Keywords
- mother-to-child transmission, HIV, pregnant women, women of reproductive age, antenatal HIV testing, antiretroviral prophylaxis, infant HIV testing, Kenya, prevention of mother-to-child transmission, HIV prevalence
- MeSH terms
- Adolescent, Adult, Age Factors, Cross-Sectional Studies, Female, Health Surveys, HIV Seropositivity, Humans, Infant, Newborn, Kenya, Health Knowledge, Attitudes, Practice, Middle Aged, Pregnancy, Pregnancy Trimesters, Prenatal Care, Prevalence, Infectious Disease Transmission, Vertical, Perinatal Care, Anti-Retroviral Agents, Live Birth, Young Adult
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