The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Gonorrhea and chlamydia case detection increased when testing increased in a multisite US HIV cohort, 2004–2014.
Open accessAbstract
OBJECTIVES: Annual screening for gonorrhea [Neisseria gonorrhoeae (NG)] and chlamydia [Chlamydia trachomatis (CT)] is recommended for all sexually active persons living with HIV but is poorly implemented. Studies demonstrating no increases in NG and/or CT (NG/CT) case detection in clinics that successfully expanded NG/CT screening raise questions about this broad screening approach. We evaluated NG/CT case detection in the HIV Research Network during 2004-2014, a period of expanding testing. METHODS: We analyzed linear time trends in annual testing (patients tested divided by all patients in care), test positivity (patients positive divided by all tested), and case detection (the number of patients with a positive result divided by all patients in care) using multivariate repeated measures logistic regression. We determined trends overall and stratified by men who have sex with men (MSM), men who have sex exclusively with women, and women. RESULTS: Among 15,614 patients (50% MSM, 26% men who have sex exclusively with women, and 24% women), annual NG/CT testing increased from 22% in 2004 to 60% in 2014 [adjusted odds ratio (AOR) per year 1.22 (1.21-1.22)]. Despite the increase in testing, test positivity also increased [AOR per year 1.10 (1.07-1.12)], and overall case detection increased from 0.8% in 2004 to 3.9% in 2014 [AOR per year 1.20 (1.17-1.22)]. Case detection was highest among MSM but increased over time among all 3 groups. CONCLUSIONS: NG/CT case detection increased as testing expanded in the population. This supports a broad approach to NG/CT screening among persons living with HIV to decrease transmission and complications of NG/CT and of HIV.
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“On the basis of available evidence, quarterly screening for gonorrhea, chlamydia, and syphilis for certain sexually active MSM can improve case finding, which can reduce the duration of infection at the population level, reduce ongoing transmission and, ultimately, prevalence among this population (228).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [228]
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STD screening of HIV-infected MSM in HIV clinics.
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Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 3,018
Metadata
- Authors
- Raifman, J. R., Gebo, K. A., Mathews, W. C., Korthuis, P. T., Ghanem, K. G., Aberg, J. A., Moore, R. D., Nijhawan, A. E., Monroe, A. K., Berry, S. A., & for the HIV Research Network
- Affiliations
- Johns Hopkins University (US)
- University of California San Diego (US)
- Oregon Health & Science University (US)
- Icahn School of Medicine at Mount Sinai (US)
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Raifman, Julia R.
- ORCID
- Venue
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2017-12-01
- Volume
- 76
- Issue
- 4
- Pages
- 409-416
- ISSN
- 1525-4135 (ISSN-L)
- PMC
- PMC5680900
- OpenAlex
- W2744332139
- Cited by
- 21
- References
- 31
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 4 · 2017: 1
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- JAIDS Journal of Acquired Immune Deficiency Syndromes (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Mental Health (K23MH105284)
- National Institute on Drug Abuse (U01DA036935)
- National Institute of Allergy and Infectious Diseases (K23AI084854, K23AI112477, P30AI036214, P30AI094189, U01AI069918, T32AI102623)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Keywords
- gonorrhea, chlamydia, Neisseria gonorrhoeae, Chlamydia trachomatis, HIV, annual screening, case finding, test positivity, men who have sex with men, sexually transmitted infections
- MeSH terms
- Adult, Chlamydia Infections, Female, Gonorrhea, Health Promotion, Humans, Male, Mass Screening, Middle Aged, Risk-Taking, Sexual Behavior, United States, HIV Infections, Prevalence, CD4 Lymphocyte Count, Viral Load, Nucleic Acid Amplification Techniques, Coinfection
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