Cited by 107Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesHIV/AIDS Research and Interventions

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A Randomized Controlled Trial of a Tailored Group Smoking Cessation Intervention for HIV-Infected Smokers

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Moadel, Alyson B., Bernstein, Steven L., Mermelstein, Robin J., Arnsten, Julia H., Dolce, Eileen H., Shuter, Jonathan·2012·JAIDS Journal of Acquired Immune Deficiency Syndromes

DOI 10.1097/qai.0b013e3182645679PMC PMC3568498

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Abstract

BACKGROUND: More than half of the persons living with human immunodeficiency virus (HIV; PLWH) in the US smoke cigarettes, and tobacco use is responsible for considerable morbidity and mortality in this group. Little is known about the efficacy of tobacco treatment strategies in PLWH. DESIGN: Randomized controlled trial comparing Positively Smoke Free (PSF), an intensive group-therapy intervention targeting HIV-infected smokers, to standard care. METHODS: A cohort of 145 PLWH smokers, recruited from an HIV-care center in the Bronx, New York, were randomized 1:1 into the PSF program or standard care. All were offered a 3-month supply of nicotine replacement therapy. PSF is an 8-session program tailored to address the needs and concerns of HIV-infected smokers. The sessions were cofacilitated by a graduate student and an HIV-infected peer. The primary outcome was biochemically confirmed, 7-day point-prevalence abstinence at 3 months. RESULTS: In the intention-to-treat analysis, PSF condition subjects had nearly double the quit rate of controls (19.2% vs. 9.7%, P = 0.11). In the complete case, as-treated analysis, assignment to PSF was associated with increased odds of quitting (odds ratio(adj) 3.55, 95% confidence interval 1.04 to 12.0). Latino ethnicity and lower loneliness score were predictive of abstinence. The subjects in the PSF condition exhibited significant decreases in daily cigarette consumption and significant increases in self-efficacy and in motivation to quit. Attendance of ≥7 sessions was associated with higher quit rates. CONCLUSIONS: These findings suggest a positive effect of PSF on cessation rates in PLWH smokers. Loneliness and self-efficacy are influential factors in the smoking behaviors of PLWH.

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Authors: Moadel, A. B., Bernstein, S. L., Mermelstein, R. J., Arnsten, J. H., Dolce, E. H., & Shuter, J.
Affiliations: Albert Einstein College of Medicine (US)
Yale University (US)
University of Illinois Chicago (US)
Corresponding author: Moadel, Alyson B.
ORCID: Bernstein, Steven L.
Mermelstein, Robin J.
Arnsten, Julia H.
Shuter, Jonathan
Venue: JAIDS Journal of Acquired Immune Deficiency Syndromes
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2012-10-01
Volume: 61
Issue: 2
Pages: 208-215
ISSN: 1525-4135 (ISSN-L)
DOI: 10.1097/qai.0b013e3182645679
PMC: PMC3568498
OpenAlex: W2024488929
Semantic Scholar: 837e8b3743aa5d391cff7732802dcfa7a3b697ec
Cited by: 107
References: 41
Citations by year: 2026: 4 · 2025: 3 · 2024: 9 · 2023: 5 · 2022: 2 · 2021: 10 · 2020: 5 · 2019: 8 · 2018: 7 · 2017: 8 · 2016: 16 · 2015: 9 · 2014: 11 · 2013: 8 · 2012: 2
FWCI: 6.43
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: JAIDS Journal of Acquired Immune Deficiency Syndromes (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse (R21DA023362)
National Cancer Institute (R21CA163100)
National Institute of Allergy and Infectious Diseases (AI-51519, P30AI051519)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Keywords: smoking cessation, group therapy, nicotine replacement therapy, peer facilitation, abstinence, loneliness, self-efficacy, Hispanic origin, Latino smokers
MeSH terms: Adult, Aged, Female, Humans, Male, Middle Aged, New York, Smoking, HIV Infections, Smoking Cessation, Treatment Outcome

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A Randomized Controlled Trial of a Tailored Group Smoking Cessation Intervention for HIV-Infected Smokers

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