Cited by 69Smoking Behavior and CessationMobile Health and mHealth ApplicationsSubstance Abuse Treatment and Outcomes

Combining text messaging and telephone counseling to increase varenicline adherence and smoking abstinence among cigarette smokers living with HIV: a randomized controlled study

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Tseng, Tuo-Yen, Krebs, Paul, Schoenthaler, Antoinette, Wong, Selena, Sherman, Scott, Gonzalez, Mirelis, Urbina, Antonio, Cleland, Charles M. +1 more·2017·AIDS and Behavior

Abstract

Smoking represents an important health risk for people living with HIV (PLHIV). Low adherence to smoking cessation pharmacotherapy may limit treatment effectiveness. In this study, 158 participants recruited from three HIV care centers in New York City were randomized to receive 12-weeks of varenicline (Chantix) either alone as standard care (SC) or in combination with text message (TM) support or TM plus cell phone-delivered adherence-focused motivational and behavioral therapy (ABT). Generalized linear mixed-effect models found a significant decline in varenicline adherence from week 1–12 across treatment groups. At 12-weeks, the probability of smoking abstinence was significantly higher in SC+TM+ABT than in SC. The study demonstrates the feasibility of delivering adherence-focused interventions to PLHIV who smoke. Findings suggest intensive behavioral support is an important component of an effective smoking cessation intervention for this population, and a focus on improving adherence self-efficacy may lead to more consistent adherence and higher smoking abstinence.

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Authors
Tseng, T.-Y., Krebs, P., Schoenthaler, A., Wong, S., Sherman, S., Gonzalez, M., Urbina, A., Cleland, C. M., & Shelley, D.
Affiliations
  • New York University (US)
  • St. Luke's-Roosevelt Hospital Center (US)
  • Center for Drug Use and HIV Research (US)
Corresponding author
Shelley, Donna
Venue
AIDS and Behavior
Published
2016-09-07
Volume
21
Issue
7
Pages
1964-1974
ISSN
  • 1090-7165 (ISSN-L)
  • 1573-3254
OpenAlex
W2508283310
Cited by
69
References
68
Citations by year
2026: 2 · 2025: 6 · 2024: 12 · 2023: 5 · 2022: 6 · 2021: 9 · 2020: 3 · 2019: 12 · 2018: 6 · 2017: 7 · 2015: 1
FWCI
6.71
Type
journal article
Language
en
Open access
Locations
  • AIDS and Behavior (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Drug Abuse (R34 DA031636001A1)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
varenicline, smoking cessation, HIV, text messaging, telephone counseling, medication adherence, smoking abstinence, adherence self-efficacy
MeSH terms
Varenicline, Adult, Behavior Therapy, Counseling, Female, Humans, Male, Middle Aged, New York City, Research Design, Smoking, Telephone, HIV Infections, Smoking Cessation, Treatment Outcome, Nicotinic Agonists, Cell Phone, Medication Adherence, Text Messaging, Motivational Interviewing

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