The DOI matches its Crossref record; 69 of the 70 references it cites were found in a registry or an index.
Adherence to the Medical Regimen During the First Two Years After Lung Transplantation
Open accessAbstract
BACKGROUND: Despite the importance of adherence to the medical regimen for maximizing health after lung transplantation, no prospective studies report on rates or risk factors for nonadherence in this patient population. Whether adherence levels differ in lung versus other types of transplant recipients is unknown. METHODS: A total of 178 lung recipients and a comparison group of 126 heart recipients were enrolled. Adherence in nine areas was assessed in separate patient and family caregiver interviews 2, 7, 12, 18, and 24 months posttransplant. Potential risk factors for nonadherence were obtained at the initial assessment. RESULTS: Cumulative incidence rates of persistent nonadherence (i.e., nonadherence at > or =2 consecutive assessments) were significantly lower (P<0.05) in lung recipients than heart recipients for taking immunosuppressants (13% nonadherent vs. 21%, respectively), diet (34% vs. 56%), and smoking (1% vs. 8%). Lung recipients had significantly higher persistent nonadherence to completing blood work (28% vs. 17%) and monitoring blood pressure (70% vs. 59%). They had a high rate of spirometry nonadherence (62%; not measured in heart recipients). The groups did not differ in nonadherence to attending clinic appointments (27%), exercise (44%), or alcohol limitations (7%). In both groups, poor caregiver support and having only public insurance (e.g., Medicaid) increased nonadherence risk in all areas. CONCLUSIONS: Lung recipients were neither uniformly better nor worse than heart recipients in adhering to their regimen. Lung recipients have particular difficulty with some home monitoring activities. Strategies to maximize adherence in both groups should build on caregiver support and on strengthening financial resources for patient healthcare requirements.
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“Other groups[41–43] suggested that in addition to medication adherence, other dimensions, such as health perception, diet, exercise, and keeping appointments and contact with the transplant center might influence outcome.”
From Adherence is associated with a favorable outcome after lung transplantation (2019) · cites this paper as [42]
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Metadata
- Authors
- Dew, M. A., DiMartini, A. F., De Vito Dabbs, A., Zomak, R., De Geest, S., Dobbels, F., Myaskovsky, L., Switzer, G. E., Unruh, M., Steel, J. L., Kormos, R. L., & McCurry, K. R.
- Affiliations
- University of Pittsburgh (US)
- University of Pittsburgh Medical Center (US)
- KU Leuven (BE)
- Corresponding author
- Dew, Mary Amanda
- ORCID
- Venue
- Transplantation
- Published
- 2008-01-27
- Volume
- 85
- Issue
- 2
- Pages
- 193-202
- ISSN
- 0041-1337 (ISSN-L)
- PMC
- PMC3387784
- OpenAlex
- W2047045261
- Cited by
- 124
- References
- 70
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 5 · 2023: 4 · 2022: 5 · 2021: 8 · 2020: 7 · 2019: 4 · 2018: 13 · 2017: 8 · 2016: 13 · 2015: 7 · 2014: 11 · 2013: 6 · 2012: 7
- FWCI
- 5.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Transplantation (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH059229, MH072718, R01MH059229, R01MH072718)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Keywords
- medication adherence, lung transplantation, heart transplantation, dietary adherence, smoking cessation, spirometry, caregiver support, Medicaid, risk factors for non-adherence, post-transplant care
- MeSH terms
- Adult, Emotions, Ethnicity, Female, Follow-Up Studies, Humans, Income, Longitudinal Studies, Male, Patient Compliance, Social Support, Heart Transplantation, Lung Transplantation, Treatment Refusal
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