The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Deep brain stimulation for chronic pain investigated with magnetoencephalography
Open accessAbstract
Deep brain stimulation has shown remarkable potential in alleviating otherwise treatment-resistant chronic pain, but little is currently known about the underlying neural mechanisms. Here for the first time, we used noninvasive neuroimaging by magnetoencephalography to map changes in neural activity induced by deep brain stimulation in a patient with severe phantom limb pain. When the stimulator was turned off, the patient reported significant increases in subjective pain. Corresponding significant changes in neural activity were found in a network including the mid-anterior orbitofrontal and subgenual cingulate cortices; these areas are known to be involved in pain relief. Hence, they could potentially serve as future surgical targets to relieve chronic pain.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“when the stimulator was turned off, worsening symptoms were associated with reduced activity in the same areas”
From Graph theory analysis of complex brain networks: new concepts in brain mapping applied to neurosurgery (2016) · cites this paper as [59]
In the citing paper
“During stimulation, subjective symptom relief was correlated with significantly increased activity in the left midanterior orbitofrontal cortex and right subgenual cingulate cortex”
From Graph theory analysis of complex brain networks: new concepts in brain mapping applied to neurosurgery (2016) · cites this paper as [59]
Citations
Cites
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Subgenual prefrontal cortex abnormalities in mood disorders
Drevets, W. C., Price, J. L., Simpson, J. R., Todd, R. D., Reich, T., Vannier, M., & Raichle, M. E. (1997) · Nature · doi:10.1038/386824a0 · Cited by 2,693
The human orbitofrontal cortex: linking reward to hedonic experience
Kringelbach, M. L. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1747 · Cited by 2,180
Self-citationPlacebo and Opioid Analgesia-- Imaging a Shared Neuronal Network
Petrovic, P., Kalso, E., Petersson, K. M., & Ingvar, M. (2002) · Science · doi:10.1126/science.1067176 · Cited by 1,488
Kringelbach, M. L. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.10.1064 · Cited by 824
Self-citationSignal Processing in Magnetoencephalography
Vrba, J., & Robinson, S. E. (2001) · Methods · doi:10.1006/meth.2001.1238 · Cited by 716
(1999) · Medical Entomology and Zoology · Cited by 587
The Oxford Companion to the Mind
Gregory, R. L. (1989) · International Clinical Psychopharmacology · doi:10.1097/00004850-198901000-00013 · Cited by 532
A Quantitative Assessment of the Sensitivity of Whole-Head MEG to Activity in the Adult Human Cortex
Hillebrand, A., & Barnes, G. R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1102 · Cited by 428
Deep brain stimulation for pain relief: A meta-analysis
Bittar, R. G., Kar-Purkayastha, I., Owen, S. L. F., Bear, R. E., Green, A. L., Wang, S., & Aziz, T. Z. (2005) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2004.10.005 · Cited by 397
Self-citation
Cited by
Sorted by citations
Affective neuroscience of pleasure: reward in humans and animals
Berridge, K. C., & Kringelbach, M. L. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1099-6 · Cited by 1,254
Self-citationTranslational principles of deep brain stimulation
Kringelbach, M. L., Jenkinson, N., Owen, S. L. F., & Aziz, T. Z. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2196 · Cited by 853
Self-citationTowards a functional neuroanatomy of pleasure and happiness
Kringelbach, M. L., & Berridge, K. C. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.08.006 · Cited by 564
Self-citationBrain States and Transitions: Insights from Computational Neuroscience
Kringelbach, M. L., & Deco, G. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108128 · Cited by 249
Self-citationBuilding a neuroscience of pleasure and well-being
Berridge, K. C., & Kringelbach, M. L. (2011) · Psychology of Well-Being: Theory, Research and Practice · doi:10.1186/2211-1522-1-3 · Cited by 229
Self-citation
Metadata
- Authors
- Kringelbach, M. L., Jenkinson, N., Green, A. L., Owen, S. L. F., Hansen, P. C., Cornelissen, P. L., Holliday, I. E., Stein, J., & Aziz, T. Z.
- Affiliations
- John Radcliffe Hospital (GB)
- University of Oxford (GB)
- Newcastle University (GB)
- Aston University (GB)
- Corresponding author
- Kringelbach, Morten L.
- Aziz, Tipu Z.
- ORCID
- Venue
- NeuroReport
- Published
- 2007-02-12
- Volume
- 18
- Issue
- 3
- Pages
- 223-228
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W1964099314
- Cited by
- 101
- References
- 26
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 6 · 2019: 4 · 2018: 5 · 2017: 5 · 2016: 3 · 2015: 10 · 2014: 6 · 2013: 6 · 2012: 10
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Neuroreport (publishedVersion)
- PubMed (publishedVersion)
- Aston Publications Explorer (Aston University) (submittedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Keywords
- deep brain stimulation, chronic pain, phantom limb pain, magnetoencephalography, orbitofrontal cortex, subgenual anterior cingulate cortex, treatment-resistant pain, surgical targets
- MeSH terms
- Brain, Brain Mapping, Chronic Disease, Gyrus Cinguli, Humans, Functional Laterality, Male, Middle Aged, Nerve Net, Pain, Intractable, Intractable Pain, Phantom Limb, Predictive Value of Tests, Magnetoencephalography, Treatment Outcome, Prefrontal Cortex, Deep Brain Stimulation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
