CoChat
Sign Up
Cited by 110

HSV-1 infection of human brain cells induces miRNA-146a and alzheimer-type inflammatory signaling.

Hill, James M., Zhao, Yuhai, Clement, Christian, Neumann, Donna M., Lukiw, Walter J.·2009·NeuroReport
DOI 10.1097/wnr.0b013e3283329c05PMC PMC2872932
Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1097/wnr.0b013e3283329c05

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 24

  1. [1]Toma HS Murina AT Areaux RG Neumann DM Bhattacharjee PS Foster TP Ocular HSV-1 latency, reactivation and recurrent disease Semin Ophthalmol 2008 23 249 273 18584563
  2. [2]Ball MJ Limbic predilection in Alzheimer dementia: is reactivated herpes virus involved? Can J Neurol Sci 1982 9 303 306 7116237
  3. [3]Itzhaki RF Wozniak MA Herpes simplex virus type 1 in Alzheimer’s disease: the enemy within J Alzheimers Dis 2008 13 393 405 18487848
  4. [4]Jamieson GA Maitland NJ Craske J Wilcock GK Itzhaki RF Detection of herpes simplex virus type 1 DNA sequences in normal and Alzheimer’s disease brain using polymerase chain reaction Biochem Soc Trans 1991 19 122S 1653719
  5. [5]Hill JM Lukiw WJ Gebhardt BM Higaki S Loutsch JM Myles ME Gene expression analyzed by microarrays in HSV-1 latent mouse trigeminal ganglion following heat stress Virus Genes 2001 23 273 280 11778695
  6. [6]Lukiw WJ Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling Neurochem Res 2004 29 1287 1297 15176485
  7. [7]Lehtinen M Koivisto V Lahtinen P Lehtinen T Aaran RK Leinikki P Phospholipase A2 activity is copurified together with herpes simplex virus-specified Fc receptor proteins Intervirology 1988 29 50 56 2838429
  8. [8]Baltimore D Boldin MP O’Connell RM Rao DS Taganov KD MicroRNAs: new regulators of immune cell development and function Nat Immunol 2008 9 839 845 18645592
  9. [9]Prerna S Lukiw WJ Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer’s disease temporal lobe neocortex Neurosci Lett 2009 459 100 104 19406203
  10. [11]Lukiw WJ Cui JG Zhao Y An NF-κB-sensitive microRNA-146a-mediated inflammatory circuit in Alzheimer’s disease and in stressed human brain cells J Biol Chem 2008 283 31315 31322 18801740 PMC2581572
  11. [12]Pogue AI Li YY Cui JG Zhao Y Kruck TPA Percy ME Characterization of an NF-κB-regulated, miRNA-146a-mediated downregulation of CFH in metal-sulfate-stressed human brain cells J Inorganic Biochem 2009 111 156 164 19540598
  12. [13]Lukiw WJ Micro RNA speciation in fetal, aged and Alzheimer hippocampus Neuroreport 2007 18 297 300 17314675
  13. [14]Lukiw WJ Pogue AI Induction of specific miRNA species by ROS-generating metal sulfates in primary human brain cells J Inorg Biochem 2007 101 1265 1269 17629564 PMC2080079
  14. [15]Higaki S Deai T Fukuda M Shimomura Y Microarray analysis in the HSV-1 latently infected mouse trigeminal ganglia Cornea 2004 23 S42 S47 15448479
  15. [16]Hill JM Ball MJ Neumann DM Azcuy AM Bhattacharjee PS Bouhanik S The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender J Virol 2008 82 8230 8234 18550674 PMC2519549
  16. [17]Alexandrov P Cui JG Zhao Y Lukiw WJ 24S-hydroxycholesterol induces inflammatory gene expression in human neural cells Neuroreport 2005 16 909 913 15931060
  17. [18]Rapoport SI In vivo approaches and rationale for quantifying kinetics and imaging brain lipid metabolic pathways Prostagland Other Lipid Mediat 2005 77 185 196 16099403
  18. [19]Higaki S Watanabe K Itahashi M Shimomura Y Cyclooxygenase-inhibiting drug reduces HSV-1 reactivation in a mouse eye model Curr Eye Res 2009 34 171 176 19274523
  19. [20]Meffert MK Baltimore D Physiological functions for brain NF-kappaB Trends Neurosci 2005 28 37 43 15626495
  20. [21]Huemer HP Wang Y Garred P Koistinen V Oppermann S Herpes simplex virus glycoprotein C: molecular mimicry of complement regulatory proteins by a viral protein Immunology 1993 79 639 647 8406590 PMC1421934
  21. [22]Faith SA Sweet TJ Bailey E Booth T Docherty JJ Resveratrol suppresses nuclear factor-κB in herpes simplex virus infected cells Antiviral Res 2006 72 242 251 16876885
  22. [23]Motsch N Pfuhl T Mrazek J Barth S Grässer FA Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miR-146a RNA Biology 2007 4 131 137 18347435
  23. [24]Hou J Wang P Lin L Liu X Ma F An H MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2 J Immunol 2009 183 2150 2158 19596990
  24. [25]Umbach JL Kramer MF Jurak I Karnowski HW Coen DM Cullen BR MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs Nature 2008 454 780 783 18596690 PMC2666538

Cited by

Sorted by citations

Authors
Hill, J. M., Zhao, Y., Clement, C., Neumann, D. M., & Lukiw, W. J.
Venue
NeuroReport
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2009-10-28
Volume
20
Issue
16
Pages
1500-1505
ISSN
0959-4965
DOI
10.1097/wnr.0b013e3283329c05
PMC
PMC2872932
Cited by
110
References
1
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review