The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Impact of sleep on the risk of cognitive decline and dementia
Open accessAbstract
PURPOSE OF REVIEW: Trouble falling or staying asleep, poor sleep quality, and short or long sleep duration are gaining attention as potential risk factors for cognitive decline and dementia, including Alzheimer's disease. Sleep-disordered breathing has also been linked to these outcomes. Here, we review recent observational and experimental studies investigating the effect of poor sleep on cognitive outcomes and Alzheimer's disease, and discuss possible mechanisms. RECENT FINDINGS: Observational studies with self-report and objective sleep measures (e.g. wrist actigraphy, polysomnography) support links between disturbed sleep and cognitive decline. Several recently published studies demonstrate associations between sleep variables and measures of Alzheimer's disease pathology, including cerebrospinal fluid measures of Aβ and PET measures of Aβ deposition. In addition, experimental studies suggest that sleep loss alters cerebrospinal fluid Aβ dynamics, decrements in slow-wave sleep may decrease the clearance of Aβ from the brain, and hypoxemia characteristic of sleep-disordered breathing increases Aβ production. SUMMARY: Findings indicate that poor sleep is a risk factor for cognitive decline and Alzheimer's disease. Although mechanisms underlying these associations are not yet clear, healthy sleep appears to play an important role in maintaining brain health with age, and may play a key role in Alzheimer's disease prevention.
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Sleep disturbances increase the risk of dementia: a systematic review and meta-analysis
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Metadata
- Authors
- Spira, A. P., Chen-Edinboro, L. P., Wu, M. N., & Yaffe, K.
- Venue
- Current Opinion in Psychiatry
- Published
- 2014-11
- Volume
- 27
- Issue
- 6
- Pages
- 478-483
- ISSN
- 0951-7367 (ISSN-L)
- OpenAlex
- W2323344600
- Cited by
- 308
- References
- 17
- FWCI
- 7.41
- Type
- journal article
- Language
- en
- Open access
- green
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- Spira, A. P., Chen-Edinboro, L. P., Wu, M. N., & Yaffe, K. (2014). Impact of sleep on the risk of cognitive decline and dementia. Current Opinion in Psychiatry. https://doi.org/10.1097/yco.0000000000000106
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
