Cited by 161Pain Management and Placebo EffectPsychosomatic Disorders and Their TreatmentsPsychotherapy Techniques and Applications

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Role of expectations in health

Colloca, Luana, Miller, Franklin G·2011·Current Opinion in Psychiatry

DOI 10.1097/yco.0b013e328343803b

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Abstract

PURPOSE OF REVIEW: Considerable progress has been made in the neurobiological understanding of expectations in physiological and pathological processes. This article is aimed at presenting an overview of the role of expectations in producing health-related effects. We selected recent laboratory and clinical studies in the field of the placebo effect, with a particular focus on psychiatric disorders. RECENT FINDINGS: Recent scientific research indicates that expectations have the potential for relieving many symptoms. This research relies mostly on the study of placebo and nocebo phenomena which influence physiological and pathological functions. The findings from placebo and nocebo research have important implications for the design and interpretation of clinical trials and for clinical practice. SUMMARY: The studies of expectations in the field of psychiatry and in other fields of medicine suggest that placebo effects are likely to be an important aspect of any treatment. The application of research on health-related expectations has the potential for promoting wellness, improving health, and benefiting patient care.

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Additional file 6 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Additional file 8 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Additional file 4 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Additional file 2 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Additional file 3 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Additional file 5 of Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects
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Authors: Colloca, L., & Miller, F. G.
Affiliations: National Institutes of Health (US)
Corresponding author: Colloca, Luana
ORCID: Colloca, Luana
Miller, Franklin G
Venue: Current Opinion in Psychiatry
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2011-03
Volume: 24
Issue: 2
Pages: 149-155
ISSN: 0951-7367 (ISSN-L)
DOI: 10.1097/yco.0b013e328343803b
OpenAlex: W2317572789
Cited by: 161
References: 52
Citations by year: 2026: 12 · 2025: 11 · 2024: 17 · 2023: 13 · 2022: 5 · 2021: 15 · 2020: 14 · 2019: 9 · 2018: 15 · 2017: 9 · 2016: 8 · 2015: 7 · 2014: 4 · 2013: 9 · 2012: 11
FWCI: 0.66
Type: journal article
Language: en
Open access: closed
Locations: Current Opinion in Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: expectations, placebo effect, nocebo effect, mental illness, symptom relief, clinical trial design, patient care, wellness
MeSH terms: Mental Disorders, Clinical Trials as Topic, Humans, Placebos, Treatment Outcome, Outcome Assessment, Health Care

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Role of expectations in health

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