Cited by 142Medication Adherence and ComplianceMental Health Treatment and AccessPharmacy and Medical Practices

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Medication nonadherence and psychiatry

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Chapman, Sarah C.E., Horne, Rob·2013·Current Opinion in Psychiatry

DOI 10.1097/yco.0b013e3283642da4PMC PMC4222796

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Abstract

PURPOSE OF REVIEW: Nonadherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing nonadherence is therefore a key challenge to quality care for patients with psychiatric disorders. This review highlights findings regarding the prevalence and consequence of nonadherence, barriers to adherence and new intervention methods from 2012 onwards. RECENT FINDINGS: Recent research has highlighted that nonadherence is a global challenge for psychiatry and has linked nonadherence to poorer outcomes, including hospital admissions, suicide and mortality. Optimizing medication regimens can reduce nonadherence; however, often a complex interplay of factors affects individuals' motivation and ability to follow their prescription. Psychiatrists can enable patients to develop an accurate model of their illness and treatment and facilitate adherence. However, nonadherence is often a hidden issue within consultations. Novel interventions using new technologies and tailoring techniques may have the potential to reduce nonadherence. SUMMARY: Nonadherence remains a significant challenge for patients with psychiatric disorders, physicians and healthcare systems. New developments demonstrate the importance of developing tailored interventions to enable patients to overcome perceptual and practical barriers to adherence.

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FIGURE 1 Perceptions and Practicalities Approach to nonadherence [5].CC BY-NC-ND · PubMed Central

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FIGURE 2 Intervention components, based on content from [5].CC BY-NC-ND · PubMed Central

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Authors: Chapman, S. C. E., & Horne, R.
Affiliations: UCL School of Pharmacy (GB)
ORCID: Chapman, Sarah C.E.
Venue: Current Opinion in Psychiatry
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2013-09
Volume: 26
Issue: 5
Pages: 446-452
ISSN: 0951-7367 (ISSN-L)
DOI: 10.1097/yco.0b013e3283642da4
PMC: PMC4222796
OpenAlex: W2026767598
Cited by: 142
References: 57
Citations by year: 2026: 3 · 2025: 8 · 2024: 7 · 2023: 12 · 2022: 15 · 2021: 18 · 2020: 18 · 2019: 11 · 2018: 15 · 2017: 12 · 2016: 7 · 2015: 11 · 2014: 4 · 2013: 1
FWCI: 1.06
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
Locations: Current Opinion in Psychiatry (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Funders: National Institute for Health and Care Research (NF-SI-0510-10197, PB-PG-1207-15248)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Keywords: medication non-adherence, mental illness, barriers to adherence, adherence interventions, personalized interventions, technology-based interventions, hospitalization, suicide, mortality, physician-patient relationship, illness model
MeSH terms: Assessment of Medication Adherence, Mental Disorders, Humans, Health Behavior, Drug Monitoring, Medication Adherence

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