The DOI matches its Crossref record.
Coinfection and the evolution of parasite virulence
Abstract
Analyses of the selection pressures acting on parasite virulence are made more complicated when individual hosts can simultaneously harbour many different strains or genotypes of a parasite. Here we explore the evolutionary dynamics of host-parasite associations in which individual hosts can be coinfected with many different parasite strains. (We take coinfection to mean that each strain transmits at a rate unaffected by the presence of others in the same host.) This study thus represents the opposite extreme to our earlier work on superinfection in which there is a dominance hierarchy such that only the most virulent strain present in a host is transmitted. For highly diverse populations of parasite strains, we find that such coinfection leads to selection for strains whose virulence-levels lie in a relatively narrow band close to the maximum consistent with the parasite's basic preproductive ratio, R0, exceeding unity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Emerging fungal threats to animal, plant and ecosystem health
Fisher, M. C., Henk, D. A., Briggs, C. J., Brownstein, J. S., Madoff, L. C., McCraw, S. L., & Gurr, S. J. (2012) · Nature · doi:10.1038/nature10947 · Cited by 3,310
Virulence evolution and the trade‐off hypothesis: history, current state of affairs and the future
ALIZON, S., HURFORD, A., MIDEO, N., & VAN BAALEN, M. (2009) · Journal of Evolutionary Biology · doi:10.1111/j.1420-9101.2008.01658.x · Cited by 932
Prisoner's dilemma in an RNA virus
Turner, P. E., & Chao, L. (1999) · Nature · doi:10.1038/18913 · Cited by 657
Imperfect vaccines and the evolution of pathogen virulence
Gandon, S., Mackinnon, M. J., Nee, S., & Read, A. F. (2001) · Nature · doi:10.1038/414751a · Cited by 630
Comparing Classical Community Models: Theoretical Consequences for Patterns of Diversity
Chave, J., Muller‐Landau, H. C., & Levin, S. A. (2002) · The American Naturalist · doi:10.1086/324112 · Cited by 573
Metadata
- Venue
- Proceedings of the Royal Society of London. Series B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 1995-08-22
- Volume
- 261
- Issue
- 1361
- Pages
- 209-215
- ISSN
- 0080-4649 (ISSN-L)
- 0962-8452
- 1471-2954
- OpenAlex
- W2033084767
- Cited by
- 729
- References
- 0
- FWCI
- 10.75
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Coinfection and the evolution of parasite virulence. https://app.cochat.ai/papers/10.1098/rspb.1995.0138
- The paper
- Coinfection and the evolution of parasite virulence. (1995). Proceedings of the Royal Society of London. Series B: Biological Sciences. https://doi.org/10.1098/rspb.1995.0138
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
