The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Medicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems
Open accessAbstract
Global pharmaceutical consumption is rising with the growing and ageing human population and more intensive food production. Recent studies have revealed pharmaceutical residues in a wide range of ecosystems and organisms. Environmental concentrations are often low, but pharmaceuticals typically are designed to have biological effects at low doses, acting on physiological systems that can be evolutionarily conserved across taxa. This Theme Issue introduces the latest research investigating the risks of environmentally relevant concentrations of pharmaceuticals to vertebrate wildlife. We take a holistic, global view of environmental exposure to pharmaceuticals encompassing terrestrial, freshwater and marine ecosystems in high- and low-income countries. Based on both field and laboratory data, the evidence for and relevance of changes to physiology and behaviour, in addition to mortality and reproductive effects, are examined in terms of the population- and community-level consequences of pharmaceutical exposure on wildlife. Studies on uptake, trophic transfer and indirect effects of pharmaceuticals acting via food webs are presented. Given the logistical and ethical complexities of research in this area, several papers focus on techniques for prioritizing which compounds are most likely to harm wildlife and how modelling approaches can make predictions about the bioavailability, metabolism and toxicity of pharmaceuticals in non-target species. This Theme Issue aims to help clarify the uncertainties, highlight opportunities and inform ongoing scientific and policy debates on the impacts of pharmaceuticals in the environment.
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Cites
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Ecosystems and Human Well-being: Synthesis
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Pharmaceuticals and personal care products in the environment: agents of subtle change?
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Occurrence, fate and effects of pharmaceutical substances in the environment- A review
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Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment
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Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?
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Self-citationClutton-Brock, T., & Sheldon, B. C. (2010) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2010.08.002 · Cited by 974
Dilute Concentrations of a Psychiatric Drug Alter Behavior of Fish from Natural Populations
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Cited by
Patel, M., Kumar, R., Kishor, K., Mlsna, T., Pittman, C. U., & Mohan, D. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00299 · Cited by 2,654
Transnational corporations and the challenge of biosphere stewardship
Folke, C., Österblom, H., Jouffray, J.-B., Lambin, E. F., Adger, W. N., Scheffer, M., Crona, B. I., Nyström, M., Levin, S. A., Carpenter, S. R., et al. (2019) · Nature Ecology & Evolution · doi:10.1038/s41559-019-0978-z · Cited by 290
Hejna, M., Kapuścińska, D., & Aksmann, A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19137717 · Cited by 279
Metadata
- Authors
- Arnold, K. E., Brown, A. R., Ankley, G. T., & Sumpter, J. P.
- Venue
- Philosophical Transactions of the Royal Society B: Biological Sciences
- Publisher
- The Royal Society
- Published
- 2014-11-19
- Volume
- 369
- Issue
- 1656
- Pages
- 20130569
- ISSN
- 0962-8436 (ISSN-L)
- 1471-2970
- OpenAlex
- W2135488502
- Cited by
- 441
- References
- 72
- FWCI
- 16.90
- Type
- journal article
- Language
- en
- Open access
- green
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- Arnold, K. E., Brown, A. R., Ankley, G. T., & Sumpter, J. P. (2014). Medicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems. Philosophical Transactions of the Royal Society B: Biological Sciences. https://doi.org/10.1098/rstb.2013.0569
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