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Cited by 1,363

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?

Open access
Boxall, Alistair B.A., Rudd, Murray A., Brooks, Bryan W., Caldwell, Daniel J., Choi, Kyungho, Hickmann, Silke, Innes, Elizabeth, Ostapyk, Kim, Staveley, Jane P., Verslycke, Tim, Ankley, Gerald T., Beazley, Karen F., Belanger, Scott E., Berninger, Jason P., Carriquiriborde, Pedro, Coors, Anja, DeLeo, Paul C., Dyer, Scott D., Ericson, Jon F., Gagné, François, Giesy, John P., Gouin, Todd, Hallstrom, Lars, Karlsson, Maja V., Larsson, D. G. Joakim, Lazorchak, James M., Mastrocco, Frank, McLaughlin, Alison, McMaster, Mark E., Meyerhoff, Roger D., Moore, Roberta, Parrott, Joanne L., Snape, Jason R., Murray-Smith, Richard, Servos, Mark R., Sibley, Paul K., Straub, Jürg Oliver, Szabo, Nora D., Topp, Edward, Tetreault, Gerald R., Trudeau, Vance L., Van Der Kraak, Glen·2012·Environmental Health Perspectives

Abstract

BACKGROUND: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. OBJECTIVE: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. DATA SOURCES: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. DATA SYNTHESIS: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f ) antibiotic resistance, and g) risk management. CONCLUSIONS: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.

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Metadata

Authors
Boxall, A. B. A., Rudd, M. A., Brooks, B. W., Caldwell, D. J., Choi, K., Hickmann, S., Innes, E., Ostapyk, K., Staveley, J. P., Verslycke, T., Ankley, G. T., Beazley, K. F., Belanger, S. E., Berninger, J. P., Carriquiriborde, P., Coors, A., DeLeo, P. C., Dyer, S. D., Ericson, J. F., Gagné, F., Giesy, J. P., Gouin, T., Hallstrom, L., Karlsson, M. V., Larsson, D. G. J., Lazorchak, J. M., Mastrocco, F., McLaughlin, A., McMaster, M. E., Meyerhoff, R. D., Moore, R., Parrott, J. L., Snape, J. R., Murray-Smith, R., Servos, M. R., Sibley, P. K., Straub, J. O., Szabo, N. D., Topp, E., Tetreault, G. R., Trudeau, V. L., & Van Der Kraak, G.
Venue
Environmental Health Perspectives
Published
2012-09
Volume
120
Issue
9
Pages
1221-1229
ISSN
  • 0091-6765 (ISSN-L)
  • 1552-9924
OpenAlex
W1971503506
Cited by
1,363
References
2
FWCI
51.61
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions? https://app.cochat.ai/papers/10.1289/ehp.1104477
The paper
Boxall, A. B. A., Rudd, M. A., Brooks, B. W., Caldwell, D. J., Choi, K., Hickmann, S., Innes, E., Ostapyk, K., Staveley, J. P., Verslycke, T., Ankley, G. T., Beazley, K. F., Belanger, S. E., Berninger, J. P., Carriquiriborde, P., Coors, A., DeLeo, P. C., Dyer, S. D., Ericson, J. F., . . . Van Der Kraak, G. (2012). Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions? Environmental Health Perspectives. https://doi.org/10.1289/ehp.1104477

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.