Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 269

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

Current concepts in the pathogenesis and treatment of chronic suppurative otitis media

Open access
Mittal, Rahul, Lisi, Christopher V., Gerring, Robert, Mittal, Jeenu, Mathee, Kalai, Narasimhan, Giri, Azad, Rajeev K., Yao, Qi, Grati, M'hamed, Yan, Denise, Eshraghi, Adrien A., Angeli, Simon I., Telischi, Fred F., Liu, Xue-Zhong·2015·Journal of Medical Microbiology
DOI 10.1099/jmm.0.000155
Open this paper in CoChat — free account

Abstract

Otitis media (OM) is an inflammation of the middle ear associated with infection. Despite appropriate therapy, acute OM (AOM) can progress to chronic suppurative OM (CSOM) associated with ear drum perforation and purulent discharge. The effusion prevents the middle ear ossicles from properly relaying sound vibrations from the ear drum to the oval window of the inner ear, causing conductive hearing loss. In addition, the inflammatory mediators generated during CSOM can penetrate into the inner ear through the round window. This can cause the loss of hair cells in the cochlea, leading to sensorineural hearing loss. Pseudomonas aeruginosa and Staphylococcus aureus are the most predominant pathogens that cause CSOM. Although the pathogenesis of AOM is well studied, very limited research is available in relation to CSOM. With the emergence of antibiotic resistance as well as the ototoxicity of antibiotics and the potential risks of surgery, there is an urgent need to develop effective therapeutic strategies against CSOM. This warrants understanding the role of host immunity in CSOM and how the bacteria evade these potent immune responses. Understanding the molecular mechanisms leading to CSOM will help in designing novel treatment modalities against the disease and hence preventing the hearing loss.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1099/jmm.0.000155

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 46 references

Cited by

See all 269

Metadata

Authors
Mittal, R., Lisi, C. V., Gerring, R., Mittal, J., Mathee, K., Narasimhan, G., Azad, R. K., Yao, Q., Grati, M., Yan, D., Eshraghi, A. A., Angeli, S. I., Telischi, F. F., & Liu, X.-Z.
Venue
Journal of Medical Microbiology
Publisher
Microbiology Society
Published
2015-10-01
Volume
64
Issue
10
Pages
1103-1116
ISSN
  • 0022-2615 (ISSN-L)
  • 1473-5644
DOI
10.1099/jmm.0.000155
OpenAlex
W1849565921
Cited by
269
References
46
FWCI
11.41
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Current concepts in the pathogenesis and treatment of chronic suppurative otitis media. https://app.cochat.ai/papers/10.1099/jmm.0.000155
The paper
Mittal, R., Lisi, C. V., Gerring, R., Mittal, J., Mathee, K., Narasimhan, G., Azad, R. K., Yao, Q., Grati, M., Yan, D., Eshraghi, A. A., Angeli, S. I., Telischi, F. F., & Liu, X.-Z. (2015). Current concepts in the pathogenesis and treatment of chronic suppurative otitis media. Journal of Medical Microbiology. https://doi.org/10.1099/jmm.0.000155

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.