The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
DeepTMHMM predicts alpha and beta transmembrane proteins using deep neural networks
Open accessAbstract
Transmembrane proteins span the lipid bilayer and are divided into two major structural classes, namely alpha helical and beta barrels. We introduce DeepTMHMM, a deep learning protein language model-based algorithm that can detect and predict the topology of both alpha helical and beta barrels proteins with unprecedented accuracy. DeepTMHMM ( https://dtu.biolib.com/DeepTMHMM ) scales to proteomes and covers all domains of life, which makes it ideal for metagenomics analyses.
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Rives, A., Meier, J., Sercu, T., Goyal, S., Lin, Z., Liu, J., Guo, D., Ott, M., Zitnick, C. L., Ma, J., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2016239118 · Cited by 3,286
Rives, A., Meier, J., Sercu, T., Goyal, S., Lin, Z., Liu, J., Guo, D., Ott, M., Zitnick, C. L., Ma, J., et al. (2019) · doi:10.1101/622803 · Cited by 3,280
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles
Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science · doi:10.1126/science.1161302 · Cited by 667
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Ning, Y., Xiao, M., Perlin, D. S., Zhao, Y., Lu, M., Li, Y., Luo, Z., Dai, R., Li, S., Xu, J., et al. (2023) · Emerging Microbes & Infections · doi:10.1080/22221751.2022.2153086 · Cited by 63
Sun, H., Luan, G., Ma, Y., Lou, W., Chen, R., Feng, D., Zhang, S., Sun, J., & Lu, X. (2023) · Nature Communications · doi:10.1038/s41467-023-36964-5 · Cited by 56
Csx28 is a membrane pore that enhances CRISPR-Cas13b–dependent antiphage defense
VanderWal, A. R., Park, J.-U., Polevoda, B., Nicosia, J. K., Molina Vargas, A. M., Kellogg, E. H., & O’Connell, M. R. (2023) · Science · doi:10.1126/science.abm1184 · Cited by 55
N-glycosylation as a eukaryotic protective mechanism against protein aggregation
Duran-Romaña, R., Houben, B., De Vleeschouwer, M., Louros, N., Wilson, M. P., Matthijs, G., Schymkowitz, J., & Rousseau, F. (2024) · Science Advances · doi:10.1126/sciadv.adk8173 · Cited by 52
Metadata
- Authors
- Hallgren, J., Tsirigos, K. D., Pedersen, M. D., Almagro Armenteros, J. J., Marcatili, P., Nielsen, H., Krogh, A., & Winther, O.
- Venue
- bioRxiv (Cold Spring Harbor Laboratory)
- Publisher
- openRxiv
- Published
- 2022-04-10
- OpenAlex
- W4223551334
- Cited by
- 1,499
- References
- 3
- Type
- posted content
- Language
- en
- Open access
- green
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