The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
The Nuclear Envelope
Open accessAbstract
The nuclear envelope (NE) is a highly regulated membrane barrier that separates the nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different proteins that have been implicated in chromatin organization and gene regulation. Although the nuclear membrane enables complex levels of gene expression, it also poses a challenge when it comes to cell division. To allow access of the mitotic spindle to chromatin, the nucleus of metazoans must completely disassemble during mitosis, generating the need to re-establish the nuclear compartment at the end of each cell division. Here, I summarize our current understanding of the dynamic remodeling of the NE during the cell cycle.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Class of Membrane Proteins Shaping the Tubular Endoplasmic Reticulum
Voeltz, G. K., Prinz, W. A., Shibata, Y., Rist, J. M., & Rapoport, T. A. (2006) · Cell · doi:10.1016/j.cell.2005.11.047 · Cited by 1,152
Lamin A-dependent nuclear defects in human aging
Scaffidi, P., & Misteli, T. (2006) · Science · doi:10.1126/science.1127168 · Cited by 1,125
The molecular architecture of the nuclear pore complex
Alber, F., Dokudovskaya, S., Veenhoff, L. M., Zhang, W., Kipper, J., Devos, D., Suprapto, A., Karni-Schmidt, O., Williams, R., Chait, B. T., et al. (2007) · Nature · doi:10.1038/nature06405 · Cited by 1,057
Dechat, T., Pfleghaar, K., Sengupta, K., Shimi, T., Shumaker, D. K., Solimando, L., & Goldman, R. D. (2008) · Genes & Development · doi:10.1101/gad.1652708 · Cited by 940
The nuclear lamina comes of age
Gruenbaum, Y., Margalit, A., Goldman, R. D., Shumaker, D. K., & Wilson, K. L. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1550 · Cited by 834
The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity
Pichler, A., Gast, A., Seeler, J. S., Dejean, A., & Melchior, F. (2002) · Cell · doi:10.1016/s0092-8674(01)00633-x · Cited by 816
Transcriptional repression mediated by repositioning of genes to the nuclear lamina
Reddy, K. L., Zullo, J. M., Bertolino, E., & Singh, H. (2008) · Nature · doi:10.1038/nature06727 · Cited by 786
Ellenberg, J., Siggia, E. D., Moreira, J. E., Smith, C. L., Presley, J. F., Worman, H. J., & Lippincott-Schwartz, J. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.138.6.1193 · Cited by 768
“Laminopathies”: A wide spectrum of human diseases
Worman, H. J., & Bonne, G. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.03.028 · Cited by 661
Nuclear Membrane Proteins with Potential Disease Links Found by Subtractive Proteomics
Schirmer, E. C., Florens, L., Guan, T., Yates, J. R., & Gerace, L. (2003) · Science · doi:10.1126/science.1088176 · Cited by 653
Cited by
Catastrophic nuclear envelope collapse in cancer cell micronuclei
Hatch, E. M., Fischer, A. H., Deerinck, T. J., & Hetzer, M. W. (2013) · Cell · doi:10.1016/j.cell.2013.06.007 · Cited by 741
Self-citationNixon-Abell, J., Obara, C. J., Weigel, A. V., Li, D., Legant, W. R., Xu, C. S., Pasolli, H. A., Harvey, K., Hess, H. F., Betzig, E., et al. (2016) · Science · doi:10.1126/science.aaf3928 · Cited by 455
RNAi Factors Are Present and Active in Human Cell Nuclei
Gagnon, K. T., Li, L., Chu, Y., Janowski, B. A., & Corey, D. R. (2014) · Cell Reports · doi:10.1016/j.celrep.2013.12.013 · Cited by 372
The AIM 2 inflammasome: Sensor of pathogens and cellular perturbations
Lugrin, J., & Martinon, F. (2018) · Immunological Reviews · doi:10.1111/imr.12618 · Cited by 333
The ER in 3D: a multifunctional dynamic membrane network
Friedman, J. R., & Voeltz, G. K. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.07.004 · Cited by 300
Metadata
- Authors
- Hetzer, M. W.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2010-02-03
- Volume
- 2
- Issue
- 3
- Pages
- a000539-a000539
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2121410884
- Cited by
- 313
- References
- 144
- Type
- posted content
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Nuclear Envelope. https://app.cochat.ai/papers/10.1101/cshperspect.a000539
- The paper
- Hetzer, M. W. (2010). The Nuclear Envelope. Cold Spring Harbor Perspectives in Biology. https://doi.org/10.1101/cshperspect.a000539
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
