Transcriptional Regulation by P53

Beckerman, R., Prives, C.·2010·Cold Spring Harbor Perspectives in Biology

Cited by (575)

Items 101–200 of 575

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  4. Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions
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  5. USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2
    Z Li, Qiongyu Hao, Jianyuan Luo, J Xiong, Sufang Zhang, Weiyi Wang, Liping Bai, W Wang, Mei‐ling Chen, Wei Wang et al. · 2015 · Oncogene
  6. p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma
    Beilei Zhang, Xinan Wang, Jiacong Deng, Haifeng Zheng, Wei Liu, Si Chen, Jie Tian, Fu Wang · 2019 · Cancer Letters
  7. Beyond effector caspase inhibition
    Alexander H. Stegh, Ronald Anthony DePinho · 2011 · Cell Cycle
  8. Emerging Roles of p53 Related lncRNAs in Cancer Progression: A Systematic Review
    Tian Lin, Pingfu Hou, Sen Meng, Fang Chen, Tao Jiang, Min-Le Li, Meilin Shi, Jin-Jin Liu, Junnian Zheng, Jin Bai · 2019 · International Journal of Biological Sciences
  9. Nuclear translocation of annexin 1 following oxygen-glucose deprivation–reperfusion induces apoptosis by regulating Bid expression via p53 binding
    Xing Li, Yin Zhao, Qian Xia, Lu Zheng, Lu Liu, Baoming Zhao, Jing Shi · 2016 · Cell Death and Disease
  10. The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl
    Nina Bacher Reuven, Julia Adler, V Meltser, Y Shaul · 2013 · Cell Death and Differentiation
  11. Not all p53 gain-of-function mutants are created equal
    Stephano S. Mello, Laura Donatella Attardi · 2013 · Cell Death and Differentiation
  12. Genetics and Biology of Pancreatic Ductal Adenocarcinoma
    Richard Francis Dunne, Aram F. Hezel · 2015 · Hematology/Oncology Clinics of North America
  13. Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells
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  14. In vitro and in vivo testing methods of epigenomic endpoints for evaluating endocrine disruptors
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  15. Novel RNA-binding activity of MYF5 enhancesCcnd1/Cyclin D1mRNA translation during myogenesis
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  16. p53’s Extended Reach: The Mutant p53 Secretome
    Evangelos Pavlakis, Thorsten Stiewe · 2020 · Biomolecules
  17. A Phase I First-in-Human Pharmacokinetic and Pharmacodynamic Study of Serdemetan in Patients with Advanced Solid Tumors
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  18. Salusin-β mediates tubular cell apoptosis in acute kidney injury: Involvement of the PKC/ROS signaling pathway
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  19. Electrical Stimulation Enhances Epidermal Proliferation in Human Cutaneous Wounds by Modulating p53–SIVA1 Interaction
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  20. Haploinsufficient tumor suppressor genes.
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  21. Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity
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  22. CerS6 Is a Novel Transcriptional Target of p53 Protein Activated by Non-genotoxic Stress
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  23. Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis
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  24. The role of the MDM2/p53 axis in antitumor immune responses
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  25. Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors
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  26. Coordination between cell proliferation and apoptosis after DNA damage in Drosophila
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  27. Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
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  28. Transcriptional Regulation of thep53Tumor Suppressor Gene in S-Phase of the Cell-Cycle and the Cellular Response to DNA Damage
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  29. Fiber Light-Coupled Optofluidic Waveguide (FLOW) Immunosensor for Highly Sensitive Detection of p53 Protein
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  30. Cytostatic and Anti-tumor Potential of Ajwa Date Pulp against Human Hepatocellular Carcinoma HepG2 Cells
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  31. Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex
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  32. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
    Gross, Kayla M., Zhou, Wenhui, Breindel, Jerrica L., Ouyang, Jian, Jin, Dexter X., Sokol, Ethan S., Gupta, Piyush B., Huber, Kathryn, Zou, Lee, Kuperwasser, Charlotte · 2019 · Cell Reports
  33. VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage
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  34. Selective killing of p53‐deficient cancer cells by SP600125
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  35. Differentiated embryo-chondrocyte expressed gene 1 regulates p53-dependent cell survival versus cell death through macrophage inhibitory cytokine-1
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  36. Targeting the Ubiquitin-Mediated Proteasome Degradation of p53 for Cancer Therapy
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  37. AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair
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  38. To repress or not to repress: This is the guardian's question
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  39. USP7 enforces heterochromatinization of p53 target promoters by protecting SUV39H1 from MDM2-mediated degradation.
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  40. Anti-cancer properties of quercetin in osteosarcoma
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  41. Heat stress: A risk factor for skin carcinogenesis
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  42. NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2
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  43. Mdm2 and MdmX as Regulators of Gene Expression
    Lynn Biderman, James L. Manley, Carol L. Prives · 2012 · Genes & Cancer
  44. The many interactions between the innate immune system and the response to radiation
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  45. Molecular signatures of ovarian diseases: Insights from network medicine perspective
    Medi Kori, Esra Göv, Kazım Yalçın Arğa · 2016 · Systems Biology in Reproductive Medicine
  46. Multivalency regulates activity in an intrinsically disordered transcription factor
    Sarah J. Clark, Janette B. Myers, Ashleigh King, Radovan Fiala, Jiří Nováček, Frederick Grant Pearce, Jörg Heierhorst, Steve Reichow, Elisar J. Barbar · 2018 · eLife
  47. Molecular docking studies, drug-likeness and in-silico ADMET prediction of some novel β-Amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives as elevators of p53 protein levels
    Zakari Ya’u Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen Eyije Abechi · 2020 · Scientific African
  48. Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2
    Jing Zhang, Shu Kan, Bryant Huang, Zhenyue Hao, Tak W. Mak, Qing Zhong · 2011 · Genes & Development
  49. Mutant p53 in cell-cell interactions
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  50. Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells
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  51. The role of p53 in the alternation of vascular functions
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  52. Serine/Threonine Kinase 17A Is a Novel p53 Target Gene and Modulator of Cisplatin Toxicity and Reactive Oxygen Species in Testicular Cancer Cells
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  53. CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage
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  54. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression
    Frédéric Lebrun-Julien, Ueli Suter · 2015 · ASN NEURO
  55. p53 Requires an Intact C-Terminal Domain for DNA Binding and Transactivation
    Hyun‐Jung Kim, Kyunghwan Kim, Jongkyu Choi, Kyu Heo, Hwa Jin Baek, Robert G. Roeder, Woojin An · 2011 · Journal of Molecular Biology
  56. Life or death
    Katharina Schlereth, Joël P. Charles, Anne Catherine Bretz, Thorsten Stiewe · 2010 · Cell Cycle
  57. Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapy
    Wissam Beaino, Yunjun Guo, Albert J. Chang, Carolyn J. Anderson · 2014 · JBIC Journal of Biological Inorganic Chemistry
  58. Long story short: p53 mediates innate immunity
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  59. HDAC5, a Key Component in Temporal Regulation of p53-Mediated Transactivation in Response to Genotoxic Stress
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  61. Aberrant expression of ETS1 and ETS2 proteins in cancer
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  62. Starvation Promotes REV1 SUMOylation and p53-Dependent Sensitization of Melanoma and Breast Cancer Cells
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  63. p53 Basic C Terminus Regulates p53 Functions through DNA Binding Modulation of Subset of Target Genes
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  64. Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription
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  65. The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System
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  66. p53 and RAD9, the DNA Damage Response, and Regulation of Transcription Networks
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  67. p53-Autophagy-Metastasis Link
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  69. LncRNAs: New Players in Gliomas, With Special Emphasis on the Interaction of lncRNAs With EZH2
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