The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.
Protein Folding in the Cytoplasm and the Heat Shock Response
Open accessAbstract
Proteins generally must fold into precise three-dimensional conformations to fulfill their biological functions. In the cell, this fundamental process is aided by molecular chaperones, which act in preventing protein misfolding and aggregation. How this machinery assists newly synthesized polypeptide chains in navigating the complex folding energy landscape is now being understood in considerable detail. The mechanisms that ensure the maintenance of a functional proteome under normal and stress conditions are also of great medical relevance, as the aggregation of proteins that escape the cellular quality control underlies a range of debilitating diseases, including many age-of-onset neurodegenerative disorders.
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1 retracted
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Gavin, A.-C., Bösche, M., Krause, R., Grandi, P., Marzioch, M., Bauer, A., Schultz, J., Rick, J. M., Michon, A.-M., Cruciat, C.-M., et al. (2002) · Nature · doi:10.1038/415141a · Cited by 4,759
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Self-citationMolecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
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Cited by
Molecular chaperones in protein folding and proteostasis
Hartl, F. U., Bracher, A., & Hayer-Hartl, M. (2011) · Nature · doi:10.1038/nature10317 · Cited by 3,381
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Bouchama, A., Abuyassin, B., Lehe, C., Laitano, O., Jay, O., O’Connor, F. G., & Leon, L. R. (2022) · Nature Reviews Disease Primers · doi:10.1038/s41572-021-00334-6 · Cited by 444
Protein Folding and Mechanisms of Proteostasis
Díaz-Villanueva, J., Díaz-Molina, R., & García-González, V. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160817193 · Cited by 338
Jovaisaite, V., Mouchiroud, L., & Auwerx, J. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.090738 · Cited by 335
Molecular mechanisms governing plant responses to high temperatures
Li, B., Gao, K., Ren, H., & Tang, W. (2018) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12701 · Cited by 323
Metadata
- Authors
- Vabulas, R. M., Raychaudhuri, S., Hayer-Hartl, M., & Hartl, F. U.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2010-12-01
- Volume
- 2
- Issue
- 12
- Pages
- a004390-a004390
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2157013283
- Cited by
- 428
- References
- 158
- Type
- posted content
- Language
- en
- Open access
- bronze
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- Vabulas, R. M., Raychaudhuri, S., Hayer-Hartl, M., & Hartl, F. U. (2010). Protein Folding in the Cytoplasm and the Heat Shock Response. Cold Spring Harbor Perspectives in Biology. https://doi.org/10.1101/cshperspect.a004390
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
