The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Phase Separation in Lipid Membranes
Open accessAbstract
Cell membranes show complex behavior, in part because of the large number of different components that interact with each other in different ways. One aspect of this complex behavior is lateral organization of components on a range of spatial scales. We found that lipid-only mixtures can model the range of size scales, from approximately 2 nm up to microns. Furthermore, the size of compositional heterogeneities can be controlled entirely by lipid composition for mixtures such as 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC)/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)/cholesterol or sphingomyelin (SM)/DOPC/POPC/cholesterol. In one region of special interest, because of its connection to cell membrane rafts, nanometer-scale domains of liquid-disordered phase and liquid-ordered phase coexist over a wide range of compositions.
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Cites
Membrane lipids: where they are and how they behave
van Meer, G., Voelker, D. R., & Feigenson, G. W. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2330 · Cited by 7,157
Self-citationLipid rafts as a membrane-organizing principle
Lingwood, D., & Simons, K. (2010) · Science · doi:10.1126/science.1174621 · Cited by 4,417
The Hydrophobic Effect: Formation of Micelles and Biological Membranes
Tanford, C. (1991) · Medical Entomology and Zoology · Cited by 3,327
Separation of Liquid Phases in Giant Vesicles of Ternary Mixtures of Phospholipids and Cholesterol
Veatch, S. L., & Keller, S. L. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74726-2 · Cited by 1,481
Lipid sorting in epithelial cells
Simons, K., & Van Meer, G. (1988) · Biochemistry · doi:10.1021/bi00417a001 · Cited by 1,371
The emerging field of lipidomics
Wenk, M. R. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1776 · Cited by 1,330
Biomembranes: molecular structure and function
(1989) · Choice Reviews Online · doi:10.5860/choice.27-0304 · Cited by 1,226
Domain Shapes and Patterns: The Phenomenology of Modulated Phases
Seul, M., & Andelman, D. (1995) · Science · doi:10.1126/science.267.5197.476 · Cited by 1,143
Vist, M. R., & Davis, J. H. (1990) · Biochemistry · doi:10.1021/bi00454a021 · Cited by 1,112
Plasma membrane phosphoinositide organization by protein electrostatics
McLaughlin, S., & Murray, D. (2005) · Nature · doi:10.1038/nature04398 · Cited by 868
Cited by
Regulation of Transmembrane Signaling by Phase Separation
Case, L. B., Ditlev, J. A., & Rosen, M. K. (2019) · Annual Review of Biophysics · doi:10.1146/annurev-biophys-052118-115534 · Cited by 303
Díaz, M., Mesa-Herrera, F., & Marín, R. (2021) · Antioxidants · doi:10.3390/antiox10060907 · Cited by 84
Lipid saturation controls nuclear envelope function
Romanauska, A., & Köhler, A. (2023) · Nature Cell Biology · doi:10.1038/s41556-023-01207-8 · Cited by 65
Beltrán-Heredia, E., Almendro-Vedia, V. G., Monroy, F., & Cao, F. J. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00312 · Cited by 25
Metadata
- Authors
- Heberle, F. A., & Feigenson, G. W.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2011-03-02
- Volume
- 3
- Issue
- 4
- Pages
- a004630-a004630
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2027504135
- Cited by
- 254
- References
- 50
- Type
- posted content
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
