DHA and Its Elaborated Modulation of Antioxidant Defenses of the Brain: Implications in Aging and AD Neurodegeneration
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DHA (docosahexaenoic acid) is perhaps the most pleiotropic molecule in nerve cell biology. This long-chain highly unsaturated fatty acid has evolved to accomplish essential functions ranging from structural components allowing fast events in nerve cell membrane physiology to regulation of neurogenesis and synaptic function. Strikingly, the plethora of DHA effects has to take place within the hostile pro-oxidant environment of the brain parenchyma, which might suggest a molecular suicide. In order to circumvent this paradox, different molecular strategies have evolved during the evolution of brain cells to preserve DHA and to minimize the deleterious effects of its oxidation. In this context, DHA has emerged as a member of the “indirect antioxidants” family, the redox effects of which are not due to direct redox interactions with reactive species, but to modulation of gene expression within thioredoxin and glutathione antioxidant systems and related pathways. Weakening or deregulation of these self-protecting defenses orchestrated by DHA is associated with normal aging but also, more worryingly, with the development of neurodegenerative diseases. In the present review, we elaborate on the essential functions of DHA in the brain, including its role as indirect antioxidant, the selenium connection for proper antioxidant function and their changes during normal aging and in Alzheimer’s disease.
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DHA exerts its indirect antioxidant action modulating thioredoxin and glutathione pathways, and DHA supplementation is beneficial in improving cognitive function in mild AD.
“DHA exerts its indirect antioxidant action modulating thioredoxin and glutathione pathways, and DHA supplementation is beneficial in improving cognitive function in mild AD [165].”
From Role of Oxidative Damage in Alzheimer’s Disease and Neurodegeneration: From Pathogenic Mechanisms to Biomarker Discovery (2021) · cites this paper as [165]
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López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982 · see citing works
Oxidative Stress and Antioxidant Defense
Birben, E., Şahiner, Ü. M., Saçkesen, C., ERZURUM, S. C., & Kalaycı, Ö. (2012) · World Allergy Organization Journal · doi:10.1097/wox.0b013e3182439613 · Cited by 4,960 · see citing works
Role of nrf2 in oxidative stress and toxicity
Ma, Q. (2013) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-011112-140320 · Cited by 4,903 · see citing works
Lipid rafts as a membrane-organizing principle
Lingwood, D., & Simons, K. (2010) · Science · doi:10.1126/science.1174621 · Cited by 4,417 · see citing works
Oxidative stress, aging, and diseases
Liguori, I., Russo, G., Curcio, F., Bulli, G., Aran, L., Della-Morte, D., Gargiulo, G., Testa, G., Cacciatore, F., Bonaduce, D., et al. (2018) · Clinical Interventions in Aging · doi:10.2147/cia.s158513 · Cited by 3,979 · see citing works
Ferroptosis: process and function
Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., Kang, R., & Tang, D. (2016) · Cell Death & Differentiation · doi:10.1038/cdd.2015.158 · Cited by 3,727 · see citing works
Łoboda, A., Damulewicz, M., Pyza, E., Józkowicz, A., & Dulak, J. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2223-0 · Cited by 2,654 · see citing works
Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts
Brown, D. A., & London, E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.r000005200 · Cited by 2,344 · see citing works
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
Yang, W. S., Kim, K. J., Gaschler, M. M., Patel, M., Shchepinov, M. S., & Stockwell, B. R. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1603244113 · Cited by 2,329 · see citing works
Brigelius-Flohé, R., & Maiorino, M. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.11.020 · Cited by 1,904 · see citing works
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
Kadry, H., Noorani, B., & Cucullo, L. (2020) · Fluids and Barriers of the CNS · doi:10.1186/s12987-020-00230-3 · Cited by 1,853 · see citing works
Lipid peroxidation in cell death
Gaschler, M. M., & Stockwell, B. R. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.10.086 · Cited by 1,852 · see citing works
Metabolism and functions of glutathione in brain
Dringen, R. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00060-x · Cited by 1,702 · see citing works
Role of ROS and RNS Sources in Physiological and Pathological Conditions
Meo, S. D., Reed, T. T., Venditti, P., & Víctor, V. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/1245049 · Cited by 1,638 · see citing works
Polyunsaturated fatty acids and their metabolites in brain function and disease
Bazinet, R. P., & Layé, S. (2014) · Nature reviews. Neuroscience · doi:10.1038/nrn3820 · Cited by 1,613 · see citing works
Cao, J. Y., & Dixon, S. J. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2194-1 · Cited by 1,515 · see citing works
Seiler, A., Schneider, M., Förster, H., Roth, S., Wirth, E. K., Culmsee, C., Plesnila, N., Kremmer, E., Rådmark, O., Wurst, W., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.07.005 · Cited by 1,470 · see citing works
Selenoproteins: Molecular Pathways and Physiological Roles
Labunskyy, V. M., Hatfield, D. L., & Gladyshev, V. N. (2014) · Physiological Reviews · doi:10.1152/physrev.00039.2013 · Cited by 1,412 · see citing works
Membrane Organization and Lipid RaftsPreprint
Simons, K., & Sampaio, J. L. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004697 · Cited by 1,068 · see citing works
Iron homeostasis and oxidative stress: An intimate relationship
Galaris, D., Barbouti, A., & Pantopoulos, K. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.118535 · Cited by 922 · see citing works
Neurovascular mechanisms of Alzheimer's neurodegeneration
Zloković, B. V. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.02.001 · Cited by 921 · see citing works
Dietary (n-3) Fatty Acids and Brain Development1
Innis, S. M. (2007) · The Journal of Nutrition · doi:10.1093/jn/137.4.855 · Cited by 906 · see citing works
Docosahexaenoic acid: Membrane properties of a unique fatty acid
Stillwell, W., & Wassall, S. R. (2003) · Chemistry and Physics of Lipids · doi:10.1016/s0009-3084(03)00101-4 · Cited by 872 · see citing works
Hambright, W. S., Fonseca, R. S., Chen, L., Na, R., & Ran, Q. (2017) · Redox Biology · doi:10.1016/j.redox.2017.01.021 · Cited by 851 · see citing works
Lipid raft microdomains and neurotransmitter signalling
Allen, J., Halverson-Tamboli, R. A., & Rasenick, M. M. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2059 · Cited by 850 · see citing works
Chemical Basis of Reactive Oxygen Species Reactivity and Involvement in Neurodegenerative Diseases
Collin, F. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102407 · Cited by 822 · see citing works
Imai, H., & Nakagawa, Y. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01197-8 · Cited by 763 · see citing works
Expression of Nrf2 in Neurodegenerative Diseases
Ramsey, C. P., Glass, C. A., Montgomery, M. B., Lindl, K. A., Ritson, G. P., Chia, L. A., Hamilton, R. L., Chu, C. T., & Jordan-Sciutto, K. L. (2007) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/nen.0b013e31802d6da9 · Cited by 760 · see citing works
Catalá, A. (2009) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2008.09.004 · Cited by 745 · see citing works
Fatty acid composition of brain phospholipids in aging and in Alzheimer’s disease
Söderberg, M., Edlund, C., Kristensson, K., & Dallner, G. (1991) · Lipids · doi:10.1007/bf02536067 · Cited by 667 · see citing works
Aksenov, M. Y., & Markesbery, W. R. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01636-6 · Cited by 661 · see citing works
Hanschmann, E., Godoy, J. R., Berndt, C., Hudemann, C., & Lillig, C. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4599 · Cited by 649 · see citing works
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection
Zhang, M., An, C., Gao, Y., Leak, R. K., Chen, J., & Zhang, F. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.09.003 · Cited by 622 · see citing works
Tocher, D., Betancor, M., Sprague, M., Olsen, R., & Napier, J. (2019) · Nutrients · doi:10.3390/nu11010089 · Cited by 615 · see citing works
Johnson, J. A., Johnson, D. A., Kraft, A. D., Calkins, M. J., Jakel, R. J., Vargas, M. R., & Chen, P. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1427.036 · Cited by 588 · see citing works
DHA Effects in Brain Development and Function
Lauritzen, L., Brambilla, P., Mazzocchi, A., Harsløf, L. B. S., Ciappolino, V., & Agostoni, C. V. (2016) · Nutrients · doi:10.3390/nu8010006 · Cited by 566 · see citing works
Direct and indirect antioxidant properties of inducers of cytoprotective proteins
Dinkova‐Kostova, A. T., & Talalay, P. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700195 · Cited by 535 · see citing works
A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression
Lin, P.-Y., Huang, S.-Y., & Su, K.-P. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.03.018 · Cited by 530 · see citing works
Neuroprotective Effect of Antioxidants in the Brain
Lee, K. H., Cha, M., & Lee, B. H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197152 · Cited by 527 · see citing works
Wu, A., Ying, Z., & Gomez-Pinilla, F. (2004) · Journal of Neurotrauma · doi:10.1089/neu.2004.21.1457 · Cited by 518 · see citing works
Selenoprotein P—Expression, functions, and roles in mammals
Burk, R. F., & Hill, K. E. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.03.026 · Cited by 516 · see citing works
Deletion of Selenoprotein P Alters Distribution of Selenium in the Mouse*
Hill, K., Zhou, J.-D., McMahan, W. J., Motley, A., Atkins, J., Gesteland, R., & Burk, R. F. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300755200 · Cited by 469 · see citing works
Typical 2‐Cys peroxiredoxins – structures, mechanisms and functions
Hall, A., Karplus, P. A., & Poole, L. B. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06985.x · Cited by 465 · see citing works
Regional Membrane Phospholipid Alterations in Alzheimer's Disease
Prasad, M. R., Lovell, M. A., Yatin, M., Dhillon, H. S., & Markesbery, W. R. (1998) · Neurochemical Research · doi:10.1023/a:1022457605436 · Cited by 440 · see citing works
Thioredoxin and Thioredoxin Target Proteins: From Molecular Mechanisms to Functional Significance
Lee, S., Kim, S. M., & Lee, R. T. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4322 · Cited by 434 · see citing works
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues
Schomburg, L., Schweizer, U., Holtmann, B., Flohé, L., Sendtner, M., & Köhrle, J. (2003) · Biochemical Journal · doi:10.1042/bj20021853 · Cited by 423 · see citing works
Lipid rafts in neuronal signaling and function.
Tsui-Pierchala, B. A., Encinas, M., Milbrandt, J., & Johnson, E. M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02215-4 · Cited by 420 · see citing works
Docosahexaenoic acid promotes neurite growth in hippocampal neurons
Calderón, F. H., & Kim, H. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02520.x · Cited by 416 · see citing works
Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease
Lovell, M. A., Ehmann, W. D., Mattson, M. P., & Markesbery, W. R. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00108-5 · Cited by 413 · see citing works
Antioxidants of Edible Mushrooms
Kozarski, M., Klaus, A., Jakovljevic, D., Todorovic, N., Vunduk, J., Petrović, P., Niksic, M., Vrvic, M., & Van Griensven, L. (2015) · Molecules · doi:10.3390/molecules201019489 · Cited by 413 · see citing works
M ECHANISM AND R EGULATION OF S ELENOPROTEIN S YNTHESIS
Driscoll, D. M., & Copeland, P. R. (2003) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.23.011702.073318 · Cited by 409 · see citing works
Tamtaji, O. R., Heidari‐Soureshjani, R., Mirhosseini, N. Z., Kouchaki, E., Bahmani, F., Aghadavod, E., Ebrahimi, M. T., & Asemi, Z. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.11.034 · Cited by 409 · see citing works
Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function
Cao, D., Kevala, K., Kim, J., Moon, H., Jun, S. B., Lovinger, D. M., & Kim, H. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06335.x · Cited by 403 · see citing works
Fabelo, N., Martín, M. V., Santpere, G., Marín, R., Torrent, L., Ferrer, I., & Díaz, M. L. (2011) · Molecular Medicine · doi:10.2119/molmed.2011.00119 · Cited by 379 · see citing works
Self-citationRedox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System
Ren, X., Zou, L., Zhang, X., Branco, V., Wang, J., Carvalho, C. M. L., Holmgren, A., & Lu, J. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6925 · Cited by 365 · see citing works
Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene
Imai, H., Hirao, F., Sakamoto, T., Sekine, K., Mizukura, Y., Saito, M., Kitamoto, T., Hayasaka, M., Hanaoka, K., & Nakagawa, Y. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00734-4 · Cited by 357 · see citing works
Involvement of Lipids in Alzheimer’s Disease Pathology and Potential Therapies
Chew, H., Solomon, V. A., & Fonteh, A. N. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00598 · Cited by 353 · see citing works
Björnstedt, M., Hámberg, M., Kumar, S., Xue, J., & Holmgren, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.20.11761 · Cited by 312 · see citing works
Formation and signaling actions of electrophilic lipids
Schopfer, F. J., Cipollina, C., & Freeman, B. A. (2011) · Chemical Reviews · doi:10.1021/cr200131e · Cited by 299 · see citing works
Selenium, selenoproteins and neurodegenerative diseases
Cardoso, B. R., Roberts, B. R., Bush, A. I., & Hare, D. J. (2015) · Metallomics · doi:10.1039/c5mt00075k · Cited by 295 · see citing works
Svennerholm, L. T., Boström, K. B., Jungbjer, B., & Olsson, L. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.63051802.x · Cited by 294 · see citing works
Identification of a selenocysteyl-tRNASer in mammalian cells that recognizes the nonsense codon, UGA
Lee, B. J., Worland, P. J., Davis, J. N., Stadtman, T. C., & Hatfield, D. L. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)81714-8 · Cited by 289 · see citing works
Mechanisms of dendritic mRNA transport and its role in synaptic tagging
Doyle, M., & Kiebler, M. A. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.278 · Cited by 288 · see citing works
Luo, Y., & Zheng, S. G. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00604 · Cited by 288 · see citing works
van Eersel, J., Ke, Y. D., Liu, X., Delerue, F., Kril, J. J., Götz, J., & Ittner, L. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1009038107 · Cited by 284 · see citing works
Alessandri, J., Guesnet, P., Vancassel, S., Astorg, P., Denis, I., Goustard, B., Aïd, S., Poumès‐Ballihaut, C., Champeil‐Potokar, G., & Lavialle, M. (2004) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:2004063 · Cited by 283 · see citing works
Solovyev, N. D. (2015) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2015.09.003 · Cited by 282 · see citing works
Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex
Martín, M. V., Fabelo, N., Santpere, G., Puig, B., Marín, R., Ferrer, I., & Díaz, M. L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1242 · Cited by 269 · see citing works
Self-citationPhase Separation in Lipid MembranesPreprint
Heberle, F. A., & Feigenson, G. W. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004630 · Cited by 254 · see citing works
Imbalances of trace elements related to oxidative damage in Alzheimer's disease brain.
Cornett, C., Markesbery, W. R., & Ehmann, W. D. (1998) · PubMed · Cited by 253 · see citing works
Omega-3 fatty acids and neuropsychiatric disorders
Young, G. S., & Conquer, J. A. (2005) · annales de biologie animale biochimie biophysique · doi:10.1051/rnd:2005001 · Cited by 252 · see citing works
Ahmed, N., Ahmed, U., Thornalley, P. J., Häger, K., Fleischer, G., & Münch, G. W. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02864.x · Cited by 238 · see citing works
He, C., Qu, X., Cui, L., Wang, J., & Kang, J. X. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904835106 · Cited by 233 · see citing works
Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease.
Basun, H., Forssell, L. G., Wetterberg, L., & Winblad, B. G. (1991) · PubMed · Cited by 228 · see citing works
Calabrese, V., Rukhsana Sultana, A., Scapagnini, G., Guagliano, E., Sapienza, M. A., Bella, R., Kański, J., Pennisi, G., Mancuso, C., Stella, A. M. G., et al. (2006) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.8.1975 · Cited by 227 · see citing works
Steinbrenner, H., & Sies, H. (2013) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2013.02.021 · Cited by 217 · see citing works
SoOderberg, M., Edlund, C., Alafuzoff, I., Kristensson, K., & Dallner, G. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10994.x · Cited by 215 · see citing works
Metal Concentrations in Plasma and Cerebrospinal Fluid in Patients with Alzheimer’s Disease
Gerhardsson, L., Lundh, T., Minthon, L., & Londos, E. (2008) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000129365 · Cited by 210 · see citing works
Selenium and selenoprotein function in brain disorders
Pillai, R., Uyehara‐Lock, J. H., & Bellinger, F. P. (2014) · IUBMB Life · doi:10.1002/iub.1262 · Cited by 201 · see citing works
Editorial: Impact of Lipid Peroxidation on the Physiology and Pathophysiology of Cell Membranes
Catalá, Á., & Díaz, M. L. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00423 · Cited by 201 · see citing works
Self-citationIshrat, T., Parveen, K., Khan, M. M., Khuwaja, G., Khan, M. B., Yousuf, S., Ahmad, A., Shrivastav, P., & Islam, F. (2009) · Brain Research · doi:10.1016/j.brainres.2009.04.010 · Cited by 199 · see citing works
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
Schipper, H. M., BENNETT, D., Liberman, A., Bienias, J. L., Schneider, J. A., Kelly, J. W., & Arvanitakis, Z. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.01.016 · Cited by 199 · see citing works
Lipidomics of Human Brain Aging and Alzheimer's Disease Pathology
Naudí, A., Cabré, R., Jové, M., Ayala, V., Gonzalo‐Benito, H., Portero‐Otín, M., Ferrer, I., & Pamplona, R. (2015) · International review of neurobiology · doi:10.1016/bs.irn.2015.05.008 · Cited by 199 · see citing works
The Mitochondrial Free Radical Theory of Aging
Barja, G. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-394625-6.00001-5 · Cited by 193 · see citing works
Selenium Level and Cognitive Function in Rural Elderly Chinese
Gao, S., Jin, Y., Hall, K. S., Liang, C., Unverzagt, F. W., Ji, R., Murrell, J. R., Cao, J., Shen, J., Ma, F., et al. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwk073 · Cited by 192 · see citing works
Farooqui, A. A., Ong, W., & Horrocks, L. A. (2004) · Neurochemical Research · doi:10.1007/s11064-004-6871-3 · Cited by 184 · see citing works
Selenium and Alzheimer's Disease: A Systematic Review
Loef, M., Schrauzer, G. N., & Walach, H. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-110414 · Cited by 182 · see citing works
Nutritional status of selenium in Alzheimer's disease patients
Cardoso, B. R., Ong, T. P., Filho, W. J., Jaluul, O., Freitas, M. I. D., & Cozzolino, S. M. F. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509992832 · Cited by 182 · see citing works
Mesa-Herrera, F., Taoro‐González, L., Valdés‐Baizabal, C., Díaz, M. L., & Marín, R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153810 · Cited by 182 · see citing works
Self-citationScheerer, P., Borchert, A., Krauß, N., Wessner, H., Gerth, C., Höhne, W. E., & Kühn, H. (2007) · Biochemistry · doi:10.1021/bi700840d · Cited by 179 · see citing works
Zhang, M., Wang, S., Mao, L., Leak, R. K., Shi, Y., Zhang, W., Hu, X., Sun, B., Cao, G., Gao, Y., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4043-13.2014 · Cited by 178 · see citing works
Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases
Park, M. H., Jo, M., Kim, Y. R., Lee, C., & Hong, J. T. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.03.018 · Cited by 175 · see citing works
Baierle, M., Nascimento, S., Moro, A. M., Brucker, N., Freitas, F., Gauer, B., Durgante, J., Bordignon, S., Zibetti, M. R., Trentini, C. M., et al. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/804198 · Cited by 173 · see citing works
Belayev, L., Khoutorova, L., Atkins, K. D., & Bazan, N. G. (2009) · Stroke · doi:10.1161/strokeaha.109.555979 · Cited by 170 · see citing works
Corcoran, N. M., Martin, D., Hutter‐Paier, B., Windisch, M., Nguyen, T. T., Nheu, L., Sundström, L., Costello, A. J., & Hovens, C. M. (2010) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2010.04.020 · Cited by 168 · see citing works
Biology of Healthy Aging and Longevity
Carmona, J. J., & Michán, S. (2016) · Revista de investigaci�n Cl�nica · doi:10.1016/s0034-8376(25)00202-5 · Cited by 166 · see citing works
Fabelo, N., Martín, M. V., Marín, R., Moreno, D., Ferrer, I., & Díaz, M. L. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.02.005 · Cited by 164 · see citing works
Self-citationDocosahexaenoic Acid Therapy of Experimental Ischemic Stroke
Belayev, L., Khoutorova, L., Atkins, K. D., Eady, T. N., Hong, S., Lü, Y., Obenaus, A., & Bazan, N. G. (2010) · Translational Stroke Research · doi:10.1007/s12975-010-0046-0 · Cited by 163 · see citing works
Power, J. H. T., & Blumbergs, P. C. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0438-3 · Cited by 155 · see citing works
Bazan, N. G. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.09.003 · Cited by 148 · see citing works
Cardoso, B. R., Apolinário, D., Bandeira, V. D. S., Busse, A. L., Magaldi, R. M., Filho, W. J., & Cozzolino, S. M. F. (2015) · European Journal of Nutrition · doi:10.1007/s00394-014-0829-2 · Cited by 145 · see citing works
General and specific lipid–protein interactions in Na,K-ATPase
Cornelius, F., Habeck, M., Kanai, R., Toyoshima, C., & KARLISH, S. J. D. (2015) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2015.03.012 · Cited by 144 · see citing works
Selenoproteins and the aging brain
Zhang, S., Rocourt, C. R. B., & Cheng, W. (2010) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2010.02.006 · Cited by 135 · see citing works
Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression
Jeong, W., Bae, S. H., Tolédano, M. B., & Rhee, S. G. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.05.020 · Cited by 129 · see citing works
Katakura, M., Hashimoto, M., Shahdat, H. M., Gamoh, S., Okui, T., Matsuzaki, K., & Shido, O. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.02.057 · Cited by 126 · see citing works
Bazan, N. G., Musto, A. E., & Knott, E. J. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8200-6 · Cited by 125 · see citing works
Savaskan, N. E., Ufer, C., Kühn, H., & Borchert, A. (2007) · Biological Chemistry · doi:10.1515/bc.2007.126 · Cited by 123 · see citing works
4-Hydroxyhexenal: A lipid peroxidation product derived from oxidized docosahexaenoic acid
van Kuijk, F. J. G. M., Holte, L. L., & Dratz, E. A. (1990) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(90)90118-h · Cited by 122 · see citing works
Role of the K eap1/ N rf2 pathway in neurodegenerative diseases
Yamazaki, H., Tanji, K., Wakabayashi, K., Matsuura, S., & Itoh, K. (2015) · Pathology International · doi:10.1111/pin.12261 · Cited by 121 · see citing works
Omega-3 Essential Fatty Acids Modulate Initiation and Progression of Neurodegenerative Disease
Peláez, R. P., Lukiw, W. J., & Bazan, N. G. (2010) · Molecular Neurobiology · doi:10.1007/s12035-010-8139-z · Cited by 120 · see citing works
Chen, L., Na, R., Gu, M., Richardson, A. G., & Ran, Q. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05603.x · Cited by 119 · see citing works
Fonteh, A. N., Cipolla, M., Chiang, J., Arakaki, X., & Harrington, M. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100519 · Cited by 116 · see citing works
Nand, S., Mishra, D., Singh, P., Vamanu, E., & Singh, M. P. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111377 · Cited by 116 · see citing works
Salminen, L. E., & Paul, R. H. (2014) · Reviews in the Neurosciences · doi:10.1515/revneuro-2014-0046 · Cited by 113 · see citing works
Vinceti, M., Chiari, A., Eichmüller, M., Rothman, K. J., Filippini, T., Malagoli, C., Weuve, J., Tondelli, M., Zamboni, G., Nichelli, P., et al. (2017) · Alzheimer s Research & Therapy · doi:10.1186/s13195-017-0323-1 · Cited by 112 · see citing works
N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid
Kim, H., & Spector, A. A. (2018) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2018.03.004 · Cited by 112 · see citing works
Savaskan, N. E., Borchert, A., Bräuer, A. U., & Kühn, H. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.03.033 · Cited by 104 · see citing works
Brain lipid concentrations in bipolar disorder
Igarashi, M., Ma, K., Gao, F., Kim, H., GREENSTEIN, D. K., Rapoport, S. I., & Rao, J. S. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.08.001 · Cited by 101 · see citing works
Zhong, X., Liu, J. R., Kyle, J. W., Hanck, D. A., & Agnew, W. S. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl068 · Cited by 97 · see citing works
楠知里, Liu, Y., Yoshizaki, T., Nakagawa, F., Ishikado, A., Kondo, M., Morino, K., Sekine, O., Ugi, S., Nishio, Y., et al. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.10.115 · Cited by 95 · see citing works
Shaikh, S. R., Cherezov, V., Caffrey, M., Stillwell, W. H., & Wassall, S. R. (2003) · Biochemistry · doi:10.1021/bi034931+ · Cited by 95 · see citing works
Asatryan, A., & Bazan, N. G. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.783076 · Cited by 95 · see citing works
Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease
Johanson, C. E., McMillan, P. N., Tavares, R., Spangenberger, A. G., Duncan, J., Silverberg, G. D., & Stopa, E. G. (2004) · Cerebrospinal Fluid Research · doi:10.1186/1743-8454-1-3 · Cited by 94 · see citing works
Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity
Ran, Q., Gu, M., Remmen, H. V., Strong, R., Roberts, J. L., & Richardson, A. G. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20868 · Cited by 93 · see citing works
Preventing metal-mediated oxidative DNA damage with selenium compounds
Battin, E. E., Zimmerman, M. T., Ramoutar, R. R., Quarles, C. E., & Brumaghim, J. L. (2011) · Metallomics · doi:10.1039/c0mt00063a · Cited by 91 · see citing works
Regional Distribution of Glutathione Peroxidase in the Adult Rat Brain
Brannan, T. S., Maker, H. S., Weiss, C., & Cohen, G. (1980) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1980.tb07102.x · Cited by 89 · see citing works
Huang, T. L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-090934 · Cited by 88 · see citing works
Towards a unified mechanistic theory of aging
Barja, G. (2019) · Experimental Gerontology · doi:10.1016/j.exger.2019.05.016 · Cited by 88 · see citing works
Monitoring the Redox Status in Multiple Sclerosis
Tanaka, M., & Vécsei, L. (2020) · Biomedicines · doi:10.3390/biomedicines8100406 · Cited by 88 · see citing works
Uğuz, A. C., & Nazıroğlu, M. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0758-5 · Cited by 85 · see citing works
4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation
Ishikado, A., Morino, K., Nishio, Y., Nakagawa, F., Mukose, A., Sono, Y., Nagisa, Y., Kondo, K., Sekine, O., Yoshizaki, T., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069415 · Cited by 83 · see citing works
Docosahexaenoic acid: brain accretion and roles in neuroprotection after brain hypoxia and ischemia
Mayurasakorn, K., Williams, J. J., Ten, V. S., & Deckelbaum, R. J. (2010) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328342cba5 · Cited by 83 · see citing works
8-OHdG in Cerebrospinal Fluid as a Marker of Oxidative Stress in Various Neurodegenerative Diseases
Gmitterová, K., Heinemann, U., Gawinecka, J., Varges, D., Ciesielczyk, B., Valkovič, P., Benetin, J., & Zerr, I. (2009) · Neurodegenerative Diseases · doi:10.1159/000237221 · Cited by 82 · see citing works
Song, G.-L., Zhang, Z.-H., Wen, L., Chen, C., Shi, Q., Zhang, Y., Ni, J., & Liu, Q. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-131805 · Cited by 81 · see citing works
Inhibition of Neuronal Apoptosis by Polyunsaturated Fatty Acids
Kim, H., Akbar, M. D., & Kim, K.-Y. (2001) · Journal of Molecular Neuroscience · doi:10.1385/jmn:16:2-3:223 · Cited by 79 · see citing works
Vučković, A., Bosello-Travain, V., Bordin, L., Cozza, G., Miotto, G., Rossetto, M., Toppo, S., Venerando, R., Zaccarin, M., Maiorino, M., et al. (2019) · FEBS Letters · doi:10.1002/1873-3468.13631 · Cited by 78 · see citing works
Montine, T. J., Peskind, E. R., Quinn, J. F., Wilson, A. M., Montine, K. S., & Galasko, D. R. (2010) · NeuroMolecular Medicine · doi:10.1007/s12017-010-8126-6 · Cited by 77 · see citing works
Gladyshev, M. I., & Sushchik, N. N. (2019) · Biomolecules · doi:10.3390/biom9090485 · Cited by 77 · see citing works
Mukherjee, P. K., Chawla, A., Loayza, M. S., & Bazan, N. G. (2007) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2007.10.022 · Cited by 76 · see citing works
Díaz, M. L., Fabelo, N., Martín, M. V., Ferrer, I., Gómez, T., & Marín, R. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-141146 · Cited by 75 · see citing works
Self-citationFabelo, N., Martín, M. V., Marín, R., Santpere, G., Aso, E., Ferrer, I., & Díaz, M. L. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31826be03c · Cited by 75 · see citing works
Self-citationDíaz, M. L., Fabelo, N., Ferrer, I., & Marín, R. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.02.022 · Cited by 75 · see citing works
Self-citationZhu, W., Ding, Y., Kong, W., Li, T., & Chen, H. (2018) · Inflammation · doi:10.1007/s10753-018-0765-z · Cited by 75 · see citing works
Omega-3 Polyunsaturated Fatty Acids in Alzheimers Disease: Key Questions and Partial Answers
Calon, F. (2011) · Current Alzheimer Research · doi:10.2174/156720511796391881 · Cited by 74 · see citing works
Zgórzyńska, E., Dziedzic, B., Gorzkiewicz, A., Stulczewski, D., Bielawska, K., Su, K., & Walczewska, A. (2017) · Pharmacological Reports · doi:10.1016/j.pharep.2017.04.009 · Cited by 74 · see citing works
Kühbacher, M., Bartel, J., Hoppe, B., Alber, D., Bukalis, G., Bräuer, A. U., BEHNE, D., & Kyriakopoulos, A. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06109.x · Cited by 73 · see citing works
Lovell, M. A., Xiong, S., Ganna Lyubartseva, A., & Markesbery, W. R. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.03.008 · Cited by 73 · see citing works
Seleno-L-Methionine Protects Against β-Amyloid and Iron/Hydrogen Peroxide-Mediated Neuron Death
Xiong, S., Markesbery, W. R., Shao, C., & Lovell, M. A. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2006.1363 · Cited by 72 · see citing works
Morris, G., Walder, K. R., Puri, B. K., Berk, M., & Maes, M. H. J. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9392-y · Cited by 69 · see citing works
Suzuki, T., Zhang, J., Miyazawa, S., Liu, Q., Farzan, M., & Yao, W. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07404.x · Cited by 68 · see citing works
Sharangdhar, T., Sugimoto, Y., Heraud-Farlow, J. E., Moya, S. M. F., Ehses, J., Mozos, I. R. D. L., Ule, J., & Kiebler, M. A. (2017) · EMBO Reports · doi:10.15252/embr.201744334 · Cited by 68 · see citing works
Bell, T. J., Miyashiro, K., Sul, J., Buckley, P. T., Lee, M. T., McCullough, R. M., Jochems, J., Kim, J., Cantor, C. R., Parsons, T. D., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015264107 · Cited by 67 · see citing works
Casañas‐Sánchez, V., Pérez, J. A. P., Fabelo, N., Quinto‐Alemany, D., & Díaz, M. L. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00203 · Cited by 66 · see citing works
Self-citationDocosahexaenoic acid confers enduring neuroprotection in experimental stroke
Hong, S., Belayev, L., Khoutorova, L., Obenaus, A., & Bazan, N. G. (2014) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2013.12.033 · Cited by 66 · see citing works
Effects of inorganic selenium compounds on oxidative DNA damage
Ramoutar, R. R., & Brumaghim, J. L. (2007) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2007.03.016 · Cited by 66 · see citing works
Cytoplasmic intron retention, function, splicing, and the sentinel RNA hypothesis
Buckley, P. T., Khaladkar, M., Kim, J., & Eberwine, J. H. (2013) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1203 · Cited by 65 · see citing works
Selenoprotein P and selenoprotein M block Zn2+-mediated Aβ42 aggregation and toxicity
Du, X., Li, H., Wang, Z., Qiu, S., Liu, Q., & Ni, J. (2013) · Metallomics · doi:10.1039/c3mt20282h · Cited by 64 · see citing works
Bell, T. J., Miyashiro, K., Sul, J., McCullough, R., Buckley, P. T., Jochems, J., Meaney, D. F., Haydon, P. G., Cantor, C. R., Parsons, T. D., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711796105 · Cited by 63 · see citing works
Cieślik, M., Czapski, G. A., Wójtowicz, S., Wieczorek, I., Wencel, P. L., Strosznajder, R. P., Jaber, V. R., Lukiw, W. J., & Strosznajder, J. B. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-01819-y · Cited by 61 · see citing works
Tatsumi, Y., Kato, A., Sango, K., Himeno, T., Kondo, M., Kato, Y., Kamiya, H., Nakamura, J., & Kato, K. (2018) · Journal of Diabetes Investigation · doi:10.1111/jdi.12931 · Cited by 60 · see citing works
“Redox lipidomics technology: Looking for a needle in a haystack”
Tyurina, Y. Y., Tyurin, V. A., Anthonymuthu, T. S., Amoscato, A. A., Sparvero, L. J., Нестерова, А. М., Baynard, M. L., Sun, W., He, R., Khaitovich, P., et al. (2019) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2019.03.012 · Cited by 59 · see citing works
Membrane raft domains and remodeling in aging brain
Colin, J., Gregory-Pauron, L., Lanhers, M.-C., Claudepierre, T., Corbier, C., Yen, F. T., Malaplate-Armand, C., & Oster, T. (2016) · Biochimie · doi:10.1016/j.biochi.2016.08.014 · Cited by 55 · see citing works
Dendritic mRNA targeting and translation.
Kindler, S., & Kreienkamp, H. (2012) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-7091-0932-8_13 · Cited by 54 · see citing works
Gupta, A., Lacoste, B., Pistell, P. J., Ingram, D. K., Hamel, É., Alaoui‐Jamali, M. A., Szarek, W. A., Vlahakis, J. Z., Su, J., Song, W., et al. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12927 · Cited by 54 · see citing works
Bazan, N. G. (2012) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2012.08.008 · Cited by 50 · see citing works
Adaptation, aging, and genomic information
Rose, M. R. (2009) · Aging · doi:10.18632/aging.100053 · Cited by 49 · see citing works
Casañas‐Sánchez, V., Pérez, J. A. P., Fabelo, N., Herrera‐Herrera, A. V., Fernández, C., Marín, R., González-Montelongo, M. D. C., & Díaz, M. L. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12833 · Cited by 48 · see citing works
Self-citationHwang (2009) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000211 · Cited by 48 · see citing works
Membrane Biophysics and Mechanics in Alzheimer's Disease
Yang, X., Askarova, S., & Lee, J. C. (2010) · Molecular Neurobiology · doi:10.1007/s12035-010-8121-9 · Cited by 47 · see citing works
Docosahexaenoic Acid Significantly Stimulates Immediate Early Response Genes and Neurite Outgrowth
Dagai, L., Naor, R. P., & Birk, R. Z. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9845-z · Cited by 45 · see citing works
Gerhardsson, L., Blennow, K., Lundh, T., Londos, E., & Minthon, L. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000233353 · Cited by 44 · see citing works
Lipid Raft Proteomics: More than Just Detergent-Resistant Membranes
Foster, L. J., & Chan, Q. W. T. (2007) · Springer eBooks · doi:10.1007/978-1-4020-5943-8_4 · Cited by 43 · see citing works
Enzymes in brain phospholipid docosahexaenoic acid accretion: A PL-ethora of potential PL-ayers
Kitson, A. P., Stark, K. D., & Duncan, R. E. (2012) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2012.06.001 · Cited by 43 · see citing works
Potential Roles of Selenium and Selenoproteins in the Prevention of Alzheimer';s Disease
Du, X., Wang, C., & Liu, Q. (2015) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026615666150827094936 · Cited by 43 · see citing works
Retinoid X Receptor α Regulates DHA-Dependent Spinogenesis and Functional Synapse Formation In Vivo
Cao, H., Li, M.-Y., Li, G., Li, S.-J., Wen, B., Lü, Y., & Yu, X. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107649 · Cited by 43 · see citing works
Selenium Compounds Prevent Amyloid β-Peptide Neurotoxicity in Rat Primary Hippocampal Neurons
Godoi, G. L., Porciúncula, L. O., Schulz, J. F., Kaufmann, F. N., da Rocha, J. B. T., Souza, D. O., Ghisleni, G., & de Almeida, H. L. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1147-4 · Cited by 42 · see citing works
Khaladkar, M., Buckley, P. T., Lee, M. T., Francis, C., Eghbal, M. M., Chuong, T., Suresh, S., Kühn, B., Eberwine, J. H., & Kim, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076194 · Cited by 41 · see citing works
Changes in Lipidome Composition during Brain Development in Humans, Chimpanzees, and Macaque Monkeys
Li, Q., Bożek, K., Xu, C., Guo, Y., Sun, J., Pääbo, S., Sherwood, C. C., Hof, P. R., Ely, J. J., Li, Y., et al. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx065 · Cited by 40 · see citing works
Anatomical Regional Differences in Selenium Levels in the Human Brain
Ramos, P., Santos, A., Pinto, N. R., Mendes, R. P., Magalhães, T., & Almeida, A. A. (2014) · Biological Trace Element Research · doi:10.1007/s12011-014-0160-z · Cited by 39 · see citing works
Sex-dependent association between selenium status and cognitive performance in older adults
Cardoso, B. R., Hare, D. J., & Macpherson, H. (2020) · European Journal of Nutrition · doi:10.1007/s00394-020-02384-0 · Cited by 38 · see citing works
Insight Into the Role of Ferroptosis in Non-neoplastic Neurological Diseases
Lei, J., Chen, Z., Song, S., Sheng, C., Song, S., & Zhu, J. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00231 · Cited by 37 · see citing works
Bang, H.-Y., Park, S., Saeidi, S., Na, H., & Surh, Y. (2017) · Molecules · doi:10.3390/molecules22060969 · Cited by 35 · see citing works
Marín, R. (2011) · Frontiers in Physiology · doi:10.3389/fphys.2011.00023 · Cited by 34 · see citing works
Self-citationDíaz, M. L., Fabelo, N., & Marín, R. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00454 · Cited by 34 · see citing works
Self-citationElevated amyloid-β plaque deposition in dietary selenium-deficient Tg2576 transgenic mice
Haratake, M., Yoshida, S., Mandai, M., Fuchigami, T., & Nakayama, M. (2013) · Metallomics · doi:10.1039/c3mt00035d · Cited by 33 · see citing works
Role of membrane biophysics in Alzheimer's–related cell pathways
Zhu, D., Bungart, B. L., Yang, X., Zhumadilov, Z. S., Lee, J. C., & Askarova, S. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00186 · Cited by 32 · see citing works
Khalili, H., Ahl, R., Cao, Y., Paydar, S., Sjölin, G., Niakan, A., Dabiri, G., & Mohseni, S. (2017) · Injury · doi:10.1016/j.injury.2017.07.005 · Cited by 30 · see citing works
Liu, J., Luo, G., & Mu, Y. (2012) · Advanced topics in science and technology in China · doi:10.1007/978-3-642-22236-8 · Cited by 29 · see citing works
The emerging role of minor intron splicing in neurological disorders
Jutzi, D., Akinyi, M. V., Mechtersheimer, J., Frilander, M. J., & Ruepp, M. (2018) · Cell Stress · doi:10.15698/cst2018.03.126 · Cited by 29 · see citing works
The Role of Selenite on Microglial Migration
PUPPA, L. D., Savaskan, N. E., Bräuer, A. U., BEHNE, D., & Kyriakopoulos, A. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1397.084 · Cited by 28 · see citing works
Santamarı́a, A., Vázquez‐Román, B., de la Cruz, V. P., González‐Cortés, C., Trejo‐Solís, C., Galván‐Arzate, S., Jara‐Prado, A., Fonseca, J. G., & Ali, S. F. (2005) · Synapse · doi:10.1002/syn.20206 · Cited by 28 · see citing works
The Multifaceted Impact of Peroxiredoxins on Aging and Disease
Radyuk, S. N., & Orr, W. C. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7452 · Cited by 28 · see citing works
Plasticity of Mouse Brain Docosahexaenoic Acid: Modulation by Diet and Age
Moriguchi, T., Harauma, A., & Salem, N. (2013) · Lipids · doi:10.1007/s11745-013-3775-5 · Cited by 27 · see citing works
Santos, G., Díaz, M. L., & Torres, N. V. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00090 · Cited by 26 · see citing works
Self-citationCrystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4
Janowski, R., Scanu, S., Niessing, D., & Madl, T. (2016) · Acta Crystallographica Section F Structural Biology Communications · doi:10.1107/s2053230x16013686 · Cited by 26 · see citing works
Dietary docosahexaenoic acid inhibits neurodegeneration and prevents stroke
Yamagata, K. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24728 · Cited by 26 · see citing works
Chouinard‐Watkins, R., Chen, C. T., Metherel, A. H., Lacombe, R. J. S., Thiès, F., Masoodi, M., & Bazinet, R. P. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2017.07.013 · Cited by 25 · see citing works
Cabré, R., Naudí, A., Domínguez-González, M., Jové, M., Ayala, V., Mota‐Martorell, N., Pradas, I., Nogueras, L., Rué, M., Portero‐Otín, M., et al. (2017) · The Journals of Gerontology Series A · doi:10.1093/gerona/glx164 · Cited by 24 · see citing works
Akerele, O. A., & Cheema, S. K. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104778 · Cited by 23 · see citing works
Díaz, M. L., Fabelo, N., Casañas‐Sánchez, V., Marín, R., Gómez, T., Quinto‐Alemany, D., & Pérez, J. A. P. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150470 · Cited by 22 · see citing works
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- [80]Ursini F. Maiorino M. Glutathione Peroxidases Encyclopedia of Biological Chemistry 2nd ed. Lennarz W.J. Lane M.D. Academic Press Waltham, MA, USA 2013 399 404 978-0-12-378631-9
- [166]Ran Q. Liang H. The Use of Gpx4 Knockout Mice and Transgenic Mice to Study the Roles of Lipid Peroxidation in Diseases and Aging BT-Studies on Experimental Models Basu S. Wiklund L. Humana Press Totowa, NJ, USA 2011 265 278 978-1-60761-956-7
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Perez-Vazquez, A., Carpena, M., Barciela, P., Cassani, L., Simal-gandara, J., & Prieto, M. (2023) · Antioxidants · doi:10.3390/antiox12030612 · Cited by 98 · see citing works
Gutierrez, L., Folch, A., Rojas, M., Cantero, J. L., Atienza, M., Folch, J., Camins, A., Ruiz, A., Papandreou, C., & Bulló, M. (2021) · Nutrients · doi:10.3390/nu13113728 · Cited by 105 · see citing works
Toledo, A. P., Reyna‐Jeldes, M., Ortega, L., Coddou, C., & Yévenes, G. E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105390 · Cited by 71 · see citing works
Davinelli, S., Medoro, A., Intrieri, M., Saso, L., Scapagnini, G., & Kang, J. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.11.017 · Cited by 65 · see citing works
Hachem, M., & Nacir, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073969 · Cited by 62 · see citing works
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Ahmed, K., Senan, E. M., Al-Wagih, K. S., Al-Azzam, M. M. A., & Alkhraisha, Z. M. (2023) · Diagnostics · doi:10.3390/diagnostics13091654 · Cited by 49 · see citing works
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Raine, A., & Brodrick, L. (2024) · Aggression and Violent Behavior · doi:10.1016/j.avb.2024.101956 · Cited by 23 · see citing works
Jové, M., Cabré, R., Mota‐Martorell, N., Martin‐Garí, M., Òbis, È., Ramos, P., Canales, I., Galo‐Licona, J. D., Sol, J., Nogueras, L., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212517 · Cited by 21 · see citing works
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Mora, I., Pérez-Santamaria, A., Tortajada-Pérez, J., Vázquez‐Manrique, R. P., Arola, L., & Puiggròs, F. (2023) · Cells · doi:10.3390/cells12151932 · Cited by 11 · see citing works
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Zhang, H., Zhao, X., Zhang, J., Liu, L., & Liu, J. (2024) · Food Reviews International · doi:10.1080/87559129.2024.2423767 · Cited by 10 · see citing works
Salinas, F. C., Ramón, A. M., Ferrer, F. C., Domingo-Carnice, A., Cordobilla, B., & Domingo, J. C. (2022) · Nutrients · doi:10.3390/nu14234956 · Cited by 10 · see citing works
Joardar, A., & Chakraborty, H. (2023) · Langmuir · doi:10.1021/acs.langmuir.3c00119 · Cited by 10 · see citing works
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Shi, Y., Bao, L., Li, Y., Ou, D., Li, J., Liu, X., Deng, N., Deng, C.-Q., Huang, X., Zhang, W., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.08.182 · Cited by 8 · see citing works
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Kim, J. P., Nho, K. T., Wang, T., Huynh, K., Arnold, M., Risacher, S. L., Bice, P. J., Han, X., Kristal, B. S., Blach, C., et al. (2023) · medRxiv · doi:10.1101/2023.06.12.23291054 · Cited by 5 · see citing works
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Валерьевна, Х. М., Khrapov, S. E., Владимирович, Ч. А., Kozhin, P. M., Romakh, L. P., Евгеньевна, С. А., Викторович, Х. С., Кандалинцева, Н. В., & Брониславовна, М. Е. (2022) · Сибирский научный медицинский журнал · doi:10.18699/ssmj20220502
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Lin, T., Hu, J., Wen, Q., Liu, X., Lin, J.-H., Shi, Q., Lin, M., & Huang, W. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1502612
Liu, J., Yang, Y., Shi, H., Wong, K. K., & Raine, A. (2025) · Criminal Behaviour and Mental Health · doi:10.1002/cbm.2368
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Li, F., Feng, Z., Li, J., Ma, L., Li, M., Li, S., Liu, S., & Tang, C. (2025) · Food Science and Human Wellness · doi:10.26599/fshw.2025.9250714
Singh, P., & Rath, S. L. (2026) · Journal of Alzheimer s Disease · doi:10.1177/13872877251411331
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Bisht, D., Prakash, D., Verma, O., & Tyagi, N. (2026) · Springer eBooks · doi:10.1007/978-981-95-4169-0_3
Rusleen, M. H. R., Mansor, N. I., Hamid, A. A., Nor, N. H. M., & Mohamed, Z. (2026) · Nutrients · doi:10.3390/nu18111819
Bai, J., Tan, G., Liao, J., Zheng, B., Wang, Y., Yang, D., Huang, X., Wang, R., & Long, D. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6c01886
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Sharma, S., & Kumar, V. (2026) · Discover Chemistry. · doi:10.1007/s44371-026-00903-2
Gomes‐Bispo, A., Dias, B., Gomes, R., Cardoso, C. L., Afonso, C. M., Lopes, P. A., Prates, J. A. M., & Bandarra, N. M. (2026) · Biochimie · doi:10.1016/j.biochi.2026.08.009
Yuan, J., Yang, R., Chen, H., Zhao, H., Chen, X., Lou, Z., Han, X., & Ma, F. (2026) · Nutrients · doi:10.3390/nu18172777
H, N. N. C., Prabhu, G. S., & Almeida, P. M. D. (2026) · All Life · doi:10.1080/26895293.2026.2740823
- Authors
- Díaz, M., Mesa-Herrera, F., & Marín, R.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- Universidad de La Laguna (ES)
- Corresponding author
- Díaz, Mario
- Venue
- Antioxidants
- Publisher
- MDPI AG
- Published
- 2021-06-03
- Volume
- 10
- Issue
- 6
- Pages
- 907
- ISSN
- 2076-3921 (ISSN-L)
- PMC
- PMC8228037
- OpenAlex
- W3167089249
- Cited by
- 84
- References
- 208
- Citations by year
- 2026: 16 · 2025: 15 · 2024: 17 · 2023: 14 · 2022: 13 · 2021: 9
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Antioxidants (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Keywords
- docosahexaenoic acid, omega-3 fatty acids, thioredoxin system, glutathione system, oxidative stress, neurodegeneration, Alzheimer's disease, brain aging, selenium, gene expression regulation, membrane fatty acids, neurogenesis, synaptic function
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