The DOI matches its Crossref record; 146 of the 146 references it cites were found in a registry or an index.
Functional Neuroanatomy of the Basal Ganglia
Open accessAbstract
The "basal ganglia" refers to a group of subcortical nuclei responsible primarily for motor control, as well as other roles such as motor learning, executive functions and behaviors, and emotions. Proposed more than two decades ago, the classical basal ganglia model shows how information flows through the basal ganglia back to the cortex through two pathways with opposing effects for the proper execution of movement. Although much of the model has remained, the model has been modified and amplified with the emergence of new data. Furthermore, parallel circuits subserve the other functions of the basal ganglia engaging associative and limbic territories. Disruption of the basal ganglia network forms the basis for several movement disorders. This article provides a comprehensive account of basal ganglia functional anatomy and chemistry and the major pathophysiological changes underlying disorders of movement. We try to answer three key questions related to the basal ganglia, as follows: What are the basal ganglia? What are they made of? How do they work? Some insight on the canonical basal ganglia model is provided, together with a selection of paradoxes and some views over the horizon in the field.
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Cites
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Cited by
The basal ganglia control the detailed kinematics of learned motor skills
Dhawale, A. K., Wolff, S. B. E., Ko, R., & Ölveczky, B. P. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00889-3 · Cited by 194
A supramodal role of the basal ganglia in memory and motor inhibition: meta-analytic evidence
Guo, Y., Schmitz, T. W., Mur, M., Ferreira, C. S., & Anderson, M. C. (2018) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.11.033 · Cited by 133
Patricio, F., Morales-Andrade, A. A., Patricio-Martínez, A., & Limón, I. D. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.595635 · Cited by 129
Neural correlates of sparse coding and dimensionality reduction
Beyeler, M., Rounds, E. L., Carlson, K. D., Dutt, N., & Krichmar, J. L. (2019) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1006908 · Cited by 104
The neurobiological reward system in Prolonged Grief Disorder (PGD): A systematic review
Kakarala, S. E., Roberts, K. E., Rogers, M., Coats, T., Falzarano, F., Gang, J., Chilov, M., Avery, J., Maciejewski, P. K., Lichtenthal, W. G., et al. (2020) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2020.111135 · Cited by 85
Metadata
- Authors
- Lanciego, J. L., Luquin, N., & Obeso, J. A.
- Venue
- Cold Spring Harbor Perspectives in Medicine
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2012-10-15
- Volume
- 2
- Issue
- 12
- Pages
- a009621-a009621
- ISSN
- 2157-1422 (ISSN-L)
- OpenAlex
- W2134155886
- Cited by
- 833
- References
- 146
- Type
- posted content
- Language
- en
- Open access
- green
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- Lanciego, J. L., Luquin, N., & Obeso, J. A. (2012). Functional Neuroanatomy of the Basal Ganglia. Cold Spring Harbor Perspectives in Medicine. https://doi.org/10.1101/cshperspect.a009621
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
