Genome Stability Requires p53
Eischen, Christine M.·2016·Cold Spring Harbor Perspectives in Medicine
Cited by (165)
Items 101–165 of 165
- “Rules” to the genetic progression of tumours deciphered: Is it time to think differently in treating oral cancer patients?Ullas Mony, Vishnu Priya Veeraraghavan · 2022 · Oral Oncology
- Integrative bioinformatic analysis of p53 and pathway alterations in two different lung cancer subtypesYun Zhang, Abie Williams-Villalobo, Jyotsna Devi Godavarthi, Faith Shakoor, Shunbin Xiong, Bin Liu · 2022 · Biochemistry and Biophysics Reports
- p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-CellsIdil I. Aigha, Essam Mohamed Abdelalim · 2023 · Stem Cell Reviews and Reports
- Mapping the chromothripsis landscape in urothelial carcinoma unravels great intratumoral and intertumoral heterogeneityYuchen Zeng, Wei Lv, Huiying Tao, Conghui Li, Shiqi Jiang, Yuan Liang, Chen Chen, Tianxi Yu, Yue Li, Shuang Wu et al. · 2024 · iScience
- Development of Traceable Mouse Models of Advanced and Metastatic Bladder CancerEmma Desponds, Konstantina Kioseoglou, Hana Zdimerova, Marco Ongaro, Grégory Verdeil, M.M. Leblond · 2024 · Cancers
- Non-small cell lung carcinoma with co-expression of thyroid transcription factor-1 and p40: a case report and literature reviewC Wei, Yishan Wang, Weijia Lu, Biyun Lin, Danhui Gan, Yuanzhi Lu · 2025 · World Journal of Surgical Oncology
- Effect of p53 gene mutation with loss of function on the expression of genes and proteins involved in cell proliferationGyeong Hee Kim, Moon‐Moo Kim · 2026 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- Antagonistic pleiotropy governing reproductive aging: evolutionary regulation of endometrial receptivityHiroshi Kobayashi, Miki Nishio, Mai Umetani, Hiroshi Shigetomi, Shogo Imanaka, Hiratsugu Hashimoto · 2026 · Reproduction
- Influence of Therapeutic Proton Beam on Glioblastoma Multiforme Proliferation Index — A Preliminary StudyAnna M Bogdali, Kamila Rawojć, Justyna U. Miszczyk, Agnieszka Panek, Monika Woźniak, K. Szewczyk, Teofila Książek, Mirosław Bik-Multanowski, Jan Swakoń, Wiktor Komenda et al. · 2020 · Acta Physica Polonica A
- Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesShengwei Li, Qian Liu, Haiying Zhou, Hui Juan Lu, Xiaosheng Wang · 2022 · Journal of Translational Medicine
- Transcriptome analysis of HEK 293T cells revealed different significance of the depletion of DNA-dependent protein kinase subunits, Ku70, Ku80, and DNA-PKcsOlga Shadrina, Irina A. Garanina, Andrey N. Anisenko, Igor I. Kireev, Marina Gottikh · 2022 · Biochimie
- Mast cell sarcoma transdifferentiated from clonally-related T-lymphoblastic leukemia upon acquisition of TP53 mutation and genetic complexityJuehua Gao, Lucy Fu, Xinyan Lu, Madina Jh. SUKHANOVA, Olga Frankfurt, Arash Mohtashamian, Amy Chadburn, Lawrence J. Jennings, Barina Aqil, Qing Chen et al. · 2021 · Leukemia & lymphoma/Leukemia and lymphoma
- Translocation of pro-apoptotic proteins through basements membrane and hemidesmosome in the corneal epithelium of the keratoconus subjectsRamachandran Samivel, Saud Ahmed Alanazi, Ibraheem S. Almahuby, Adnan Ali Khan, Omar Kirat, Essam Saad Almutleb, Ali Mohammed Masmali · 2022 · Journal of King Saud University - Science
- Exploring chromosomal instability and clonal heterogeneity in breast cancerGiovanny Castellanos, Laura Valentina Camargo-Herrera, Nelson Rangel, Guillermo Jiménez, María Martínez‐Agüero, Milena Rondón‐Lagos · 2024 · Endocrine Related Cancer
- Impact of lead (Pb)-induced neurotoxicity on protein synthesis and cellular stress responses in LUHMES cellsTsunehiko Hongen, Tomohiro Ito, Xian‐Yang Qin, Hideko Sone · 2025 · Journal of Trace Elements in Medicine and Biology
- TP53 Splice Mutations Have Tumour-Independent Effects on Genomic Stability and Prognosis: An In Silico StudyApeksha Arun Bhandarkar, Noah Ethan Kelly-Foleni, Debina Sarkar, Aaron R. Jeffs, Tania L. Slatter, Antony W. Braithwaite, Sunali Y. Mehta · 2025 · International Journal of Molecular Sciences
- Potential Synergistic Roles of Ketogenic Diet and Stem Cell Therapy in Parkinson's Disease: A Narrative ReviewPrincy Sindurakar, Vasavi Rakesh Gorantla, Dovenia S. Ponnoth · 2026 · Cureus
- Geniposide enhances cisplatin sensitivity in non-small cell lung cancer through PUMA-mediated apoptotic pathwayJingjing Sun, YaoZu Han, Chen Wang, T Y Wang, Wenmin Hu, Mengchao Yu, YIXUAN WANG, Wei Han · 2026 · Cellular Signalling
- YBX1 Expression Marks Proliferative Tumour States with Context-Dependent Genomic Instability: A Pan-Cancer AnalysisS.S. Wang, Zahra Shafaei Pishabad, Debina Sarkar, Apeksha Arun Bhandarkar, Makhdoom Sarwar, Aaron R. Jeffs, Glen Reid, Antony W. Braithwaite, Sunali Y. Mehta · 2026 · International Journal of Molecular Sciences
- Flavonoids as Modulators of the p53–Bcl-2 Axis in Cancer: Molecular Mechanisms and Therapeutic ImplicationsJulia Jankowska, Łukasz Szeleszczuk, Dariusz Maciej Pisklak · 2026 · Pharmaceutics
- Potential factors contributing to extreme longevity in the Greenland sharkFrancisco Alejandro Lagunas‐Rangel · 2026 · Journal of Fish Biology
- In silico analysis prediction of HepTH1-5 as a potential therapeutic agent by targeting tumour suppressor protein networksWan-Atirah Azemin, Nadiawati Alias, Abdul Manaf Ali, Mohd Shahir Shamsir · 2021 · Journal of Biomolecular Structure and Dynamics
- Animal Models of MelanomaZackie Aktary, Martin McMahon, Lionel Larue · 2019 · Springer eBooks
- The Genomics of Liposarcoma: A Review and CommentaryHannah C. Beird, Alexander J. Lazar, Danh D. Truong · 2022 · Global Journal of Human Social Science
- Jun Dimerization Protein 2 (JDP2) Increases p53 Transactivation by Decreasing MDM2Kasey Price, William Harry Yang, Leticia Cardoso, Chiung‐Min Wang, Richard H. Yang, Wei‐Hsiung Yang · 2024 · Cancers
- Genomic Applications in Thyroid CancerThomas J. Giordano · 2018 · Springer eBooks
- Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppressionAnn Rancourt, Sachiko Sato, Masahiko S. Satoh · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Aberrant CDK1 Activity in S Phase Induces Chromosomal Instability by Increasing Mitotic Microtubule Polymerisation Rates in Colorectal Cancer CellsAnn-Kathrin Schmidt · 2021
- Role of hepatic glucose signaling in the development of liver diseaseLei Yu · 2020
- The adenoviral protein E4orf4: a probing tool to decipher mechanical stress-induced nuclear envelope remodeling in tumor cellsKévin Jacquet, Marc‐Antoine Rodrigue, Darren E. Richard, Josée N. Lavoie · 2020 · Cell Cycle
- The SARS-CoV-2 host cell membrane fusion protein TMPRSS2 is a tumor suppressor and its downregulation correlates with increased antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Zhilan Zhang, Qiushi Feng, Xiaosheng Wang · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- The SARS-CoV-2 host cell membrane fusion protein TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Zhilan Zhang, Qiushi Feng, Xiaosheng Wang · 2021 · Research Square
- The SARS-CoV-2 Host Cell Membrane Fusion Protein TMPRSS2 is A Tumor Suppressor and its Downregulation Promotes Antitumor Immunity and Immunotherapy Response in Lung AdenocarcinomaZhixian Liu, Zhilan Zhang, Qiushi Feng, Xiaosheng Wang · 2021 · Research Square
- A preview of selected articlesStuart P. Atkinson · 2020 · Stem Cells
- Extrachromosomal DNA in the cancerous transformation of Barrett’s esophagusJens Luebeck, Alvin Wei Tian Ng, Patricia C. Galipeau, Xiaohong Li, Carissa A. Sanchez, Annalise Katz‐Summercorn, Hoon Kim, Sriganesh Jammula, Yudou He, Scott Michael Lippman et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- The SARS-CoV-2 host cell membrane fusion protein TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaXiaosheng Wang, Zhixian Liu, Zhilan Zhang, Qiushi Feng · 2022 · Research Square
- Data from Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003Cassie Kline, Payal Jain, Lindsay Baker Kilburn, Erin E. Bonner, Nalin M. Gupta, John Ross Crawford, Anu Banerjee, Roger J. Packer, Javier E. Villanueva-Meyer, Tracy L. Luks et al. · 2023
- Data from Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003Cassie Kline, Payal Jain, Lindsay Baker Kilburn, Erin E. Bonner, Nalin M. Gupta, John Ross Crawford, Anu Banerjee, Roger J. Packer, Javier E. Villanueva-Meyer, Tracy L. Luks et al. · 2023
- Chronic treatment with ATR and CHK1 inhibitors does not substantially increase the mutational burden of human cellsLisa Casimir, Samuel Zimmer, Félix Racine-Brassard, Félix Goudreau, Pierre‐Étienne Jacques, Alexandre Maréchal · 2023 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
- Ferroptosis-related genes are involved in the activity of resveratrol against esophageal cancerXiujing Chen, Hongjie Chen, Penghui Hu, Yiguang Lin, Zengcheng Zou, Size Chen · 2023 · Research Square
- Pinpointing the decisive role of TP53 mutations in orchestrating immunosuppression in head and neck squamous cell carcinomaTiansheng Wang, Jie Yuan, Yuxin Cao, Xinrong Liu, Wentao Yu, Yilei Zhang, Feifei Liao, Chao Zhang, Liyan Ji, Qiongzhi He et al. · 2024 · Research Square
- Additional file 1 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesShengwei Li, Qian Liu, Haiying Zhou, Hui Juan Lu, Xiaosheng Wang · 2022 · Figshare
- Additional file 2 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesShengwei Li, Qian Liu, Haiying Zhou, Hui Juan Lu, Xiaosheng Wang · 2022 · Figshare
- Additional file 4 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesShengwei Li, Qian Liu, Haiying Zhou, Hui Juan Lu, Xiaosheng Wang · 2022 · Figshare
- Polyploidy involves the activation of mTORC1 and induces tolerance to glucose starvationDebopriya Choudhury, Didhiti Singha, Meghna Mondal, Pushkar Malakar · 2024 · Research Square
- Stepwise to clarify differentiation between pleomorphic xanthoastrocytoma and giant cell glioblastoma using p53, CD34 and KI67; clinicopathological hospital based studyAbdelhakeem A. Essa, Ahmed Abd Esattar Abd Elhakeem, Amr M. Tayel, Ahmad Abdalla Ismail · 2024 · The Egyptian Journal of Neurology Psychiatry and Neurosurgery
- Molecular Heterogeneity Analysis and Prognostic Stratification of Driver-Gene mutated NSCLC Based on Concurrent Alteration ProfilesJiamei Jin, Wenjin Pan, Yiming Liu, Wenhan Cai, Kai Zhao, Zirui Zhu, Herui Han, Mingming Hu, Xiangming Qiu, Xinran Tian et al. · 2025 · Research Square
- Additional file 3 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesLi, Shengwei, Liu, Qian, Zhou, Haiying, Lu, Hui, Xiaosheng Wang · 2022 · Figshare
- Additional file 2 of DEPTH2: an mRNA-based algorithm to evaluate intratumor heterogeneity without reference to normal controlsSong, Dandan, Wang, Xiaosheng · 2022 · Figshare
- Additional file 6 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesLi, Shengwei, Liu, Qian, Zhou, Haiying, Lu, Hui, Xiaosheng Wang · 2022 · Figshare
- Additional file 3 of TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Lu, Qiqi, Zhang, Zhilan, Qiushi Feng, Xiaosheng Wang · 2024 · Figshare
- Additional file 7 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesLi, Shengwei, Liu, Qian, Zhou, Haiying, Lu, Hui, Xiaosheng Wang · 2022 · Figshare
- Additional file 3 of DEPTH2: an mRNA-based algorithm to evaluate intratumor heterogeneity without reference to normal controlsSong, Dandan, Xiaosheng Wang · 2022 · Figshare
- Additional file 4 of TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Lu, Qiqi, Zhang, Zhilan, Qiushi Feng, Xiaosheng Wang · 2024 · Figshare
- Additional file 5 of Subtyping of sarcomas based on pathway enrichment scores in bulk and single cell transcriptomesLi, Shengwei, Liu, Qian, Zhou, Haiying, Lu, Hui, Xiaosheng Wang · 2022 · Figshare
- Additional file 2 of TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Lu, Qiqi, Zhang, Zhilan, Qiushi Feng, Xiaosheng Wang · 2024 · Figshare
- Additional file 1 of TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinomaZhixian Liu, Lu, Qiqi, Zhang, Zhilan, Qiushi Feng, Xiaosheng Wang · 2024 · Figshare
- Comparison of levels of expression of mammalian target of rapamycin (mTOR) and glutathione S-transferases (zeta, sigma, and kappa) in pterygium and normal conjunctival tissuesG. Kilic, R. Karadag, Arzu Kaya Koçdoğan, Serpil Oğuztüzün, GG Simsek · 2025 · Journal Français d Ophtalmologie
- Evaluation of Preventive Efficacy of Different Phytocompounds to Combat Hyperglycemia in Mice Model: A Comparative AssessmentSayoni Dam, Sujan Murmu, Amar Faruk Saheb, Tamanna Khatun, Barsha Roy, Astha Saha, Debapriya Ghosh, Ashaporna Biswas, Banani Bhattacharjee, Arnob Chakrovorty et al. · 2026 · Springer eBooks
- The role of the transcription factor BRN2 in melanomagenesisMichael HAMM · 2018 · theses.fr (ABES)
- Regulation of Netrin-1 by p53 isoformsYan Sun · 2020
- Double jeopardy: how BRCA2, TP53, and DNMT3A redefine the link between infertility and cancer riskZhengbin Huang, Musavir Abbas, Ansar Hussain, Ming Long, Muhammad Muzammal, Kaiyong Song · 2026 · Frontiers in Cell and Developmental Biology
- Impact of TP53 co-mutations on the efficacy of tyrosine kinase inhibitors in ALK fusion-positive non–small cell lung cancer: a systematic review and meta-analysisJiayun Ma, Siyu Li, Xingru Ao, Weixing Zhao · 2026 · Egyptian Journal of Bronchology
- Network-based discovery of resveratrol’s key regulators in lung squamous cell carcinomaDini Maharani, Jonathan García-Román, Adam Hermawan · 2026 · Egyptian Journal of Medical Human Genetics
- PRMT1-mediated methylation controls OFIP ubiquitination and centrosome duplication to maintain epidermal homeostasisKai Liu, Ting Song, Junkui Zhao, Shaodong Yan, Weiwen Bu, Shenying Zhang, Die Hu, Dengwen Li, Huijie Zhao, Jun Zhou · 2026 · Proceedings of the National Academy of Sciences