Cytokines in Cancer Immunotherapy

Waldmann, Thomas A.·2018·Cold Spring Harbor Perspectives in Biology

Cited by (504)

Items 201–300 of 504

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  6. Modulation of T cell function and survival by the tumor microenvironment
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  7. In vivo tracking of adenoviral-transduced iron oxide-labeled bone marrow-derived dendritic cells using magnetic particle imaging
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  8. The mechanism of cytokine regulation of cancer occurrence and development in the tumor microenvironment and its application in cancer treatment: a narrative review
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  9. High expression level of interleukin-1β is correlated with poor prognosis and PD-1 expression in patients with lung adenocarcinoma
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  10. The use of adenoviral vectors in gene therapy and vaccine approaches
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  11. Immunocyte membrane-derived biomimetic nano-drug delivery system: a pioneering platform for tumour immunotherapy
    Yuan-ye Zeng, Qing Gu, Dan Li, Ai-Xue Li, Rongmei Liu, Jianying Liang, Jiyong Liu · 2024 · Acta Pharmacologica Sinica
  12. Nanoparticles: Properties and Applications in Cancer Immunotherapy
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  13. Cancer Immunotherapy in Combination with Radiotherapy and/or Chemotherapy: Mechanisms and Clinical Therapy
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  14. Unlocking the potential of the tumor microenvironment for cancer therapy
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  15. Cancer nanomedicine: emergence, expansion, and expectations
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  16. Cytokine-overexpressing dendritic cells for cancer immunotherapy
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  17. Targeting the TLR2 Receptor With a Novel Thymopentin-Derived Peptide Modulates Immune Responses
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  18. Review and prospect of immune checkpoint blockade therapy represented by PD-1/PD-L1 in the treatment of clear cell renal cell carcinoma
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  19. A self‐assembled, genetically engineered, irradiated tumor cell debris vaccine
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  20. The role of cytokines in shaping the future of Cancer immunotherapy
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  21. Immunization of Mice with Gold Nanoparticles Conjugated to Thermostable Cancer Antigens Prevents the Development of Xenografted Tumors
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  22. Promising immunotherapy: Highlighting cytokine‐induced killer cells
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  23. EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy
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  24. Construction of VSVΔ51M oncolytic virus expressing human interleukin-12
    Rwaa Hussin Abdulal, Jana S. Malki, Ezdehar Abdulraouf Ghazal, Ahdab Alsaieedi, Sarah A. Almahboub, Muhammad Yasir Khan, Reem M. Alsulaiman, Mazen M. Ghaith, Turki S. Abujamel, Magdah Ganash et al. · 2023 · Frontiers in Molecular Biosciences
  25. Immune Checkpoint Inhibitors, Small-Molecule Immunotherapies and the Emerging Role of Neutrophil Extracellular Traps in Therapeutic Strategies for Head and Neck Cancer
    Connor H. O’Meara, Zuhayr Jafri, Levon Michael Khachigian · 2023 · International Journal of Molecular Sciences
  26. Development of Recombinant Oncolytic rVSV-mIL12-mGMCSF for Cancer Immunotherapy
    Anastasia Ryapolova, Ekaterina Minskaia, Nizami B. Gasanov, Vasiliy Moroz, Bogdan Krapivin, Alexander D. Egorov, Victor S. Laktyushkin, Sofia Zhuravleva, Maksim Nagornych, Е. Н. Субчева et al. · 2023 · International Journal of Molecular Sciences
  27. Nucleic acid cancer vaccines targeting tumor related angiogenesis. Could mRNA vaccines constitute a game changer?
    Srdan Tadic, Alfredo Martı́nez · 2024 · Frontiers in Immunology
  28. Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies
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  29. Current Immunotherapy Approaches for Malignant Melanoma
    Jaesung Lim, Eunjin Cho, Kyungwoo Lee, Yonghyun Choi, Youngmin Seo, Hojeong Jeon, Jonghoon H. Choi · 2019 · BioChip Journal
  30. Serum proteomic analysis of melanoma patients with immunohistochemical profiling of primary melanomas and cultured cells: Pilot study
    Jan Kučera, Karol�na Strnadov�, Barbora Dvoř�nkov�, Lukáš Lacina, Ivana Krajsov�, Jiří Štork, Hana Kov�řov�, Helena Skaln�kov�, Petr Vodička, Jan Motl�k et al. · 2019 · Oncology Reports
  31. Impact of T-cell immunity on chemotherapy response in childhood acute lymphoblastic leukemia
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  32. Coagulation- and fibrinolysis-related genes for predicting survival and immunotherapy efficacy in colorectal cancer
    Yanling Ma, Bofang Wang, Puyi He, Wenbo Qi, Ling Xiang, Ewetse Paul Maswikiti, Hao Chen · 2022 · Frontiers in Immunology
  33. Cytokine profiling identifies circulating IL-6 and IL-15 as prognostic stratifiers in patients with non-small cell lung cancer receiving anti-PD-1/PD-L1 blockade therapy
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  34. Sleep loss impairs blood-brain barrier function: Cellular and molecular mechanisms
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  35. Revolutionizing cancer treatment: the rise of personalized immunotherapies
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  36. New insights into the role of IFN-α/β and TLR7/8/9 in cancer immunotherapy and systemic autoimmunity
    Arthur Μ. Krieg · 2025 · Journal for ImmunoTherapy of Cancer
  37. Association of functional IL16 polymorphisms with cancer and cardiovascular disease: a meta-analysis
    Victor Hugo de Souza, Josiane Bazzo de Alencar, Bruna Tiaki Tiyo, Hugo Vicentin Alves, Evelyn Castillo Lima Vendramini, Ana Maria Sell, Jeane Eliete Laguila Visentainer · 2020 · Oncotarget
  38. NIR‐II Light Powered Asymmetric Hydrogel Nanomotors for Enhanced Immunochemotherapy
    Yingfei Wang, Wei Chen, Zhong Wang, Yu Zhu, Hongxia Zhao, Kun Wu, Jie Wu, Weihua Zhang, Qing Zhang, Hongqian Guo et al. · 2022 · Angewandte Chemie
  39. Prognostic and immunological significance of an M1 macrophage-related gene signature in osteosarcoma
    Xiaoyu Mao, Fanglong Song, Ju Jin, Bin Zou, Peijun Dai, Mingjuan Sun, Weicheng Xu, Lianghua Wang, Yifan Kang · 2023 · Frontiers in Immunology
  40. Therapeutic applications of RNA nanostructures
    Theresa Yip, Xiaodong Qi, Hao Yan, Yung Chang · 2024 · RSC Advances
  41. Inflammation-associated drug resistance and tumor growth in TNBC
    Arij Fouzat Hassan, Hadeel Kheraldine, Lama Abujamous, Hamda Al-Thawadi, Abdelbary M. A. Elhissi · 2025 · Frontiers in Immunology
  42. Emerging interleukin targets in the tumour microenvironment: implications for the treatment of gastrointestinal tumours
    Lindsay K. Dickerson, Jason A. Carter, Karan Kohli, Venu Gopal Pillarisetty · 2023 · Gut
  43. Predictive value of serum cytokines in patients with non-small-cell lung cancer receiving anti-PD-1 blockade therapy: a meta-analysis
    Qian Liu, Zakari Shaibu, Aiguo Xu, Fang Yang, Ruoxue Cao, Fumeng Yang · 2025 · Clinical and Experimental Medicine
  44. Interleukin-21 engineering enhances CD19-specific CAR-NK cell activity against B-cell lymphoma via enriched metabolic pathways
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  45. The Heterogeneity of Infiltrating Macrophages in Metastatic Osteosarcoma and Its Correlation with Immunotherapy
    Zhanchao Wang, Huiqiao Wu, Yu Chen, Huajiang Chen, Wen Yuan, Xinwei Wang · 2021 · Journal of Oncology
  46. Association of CTLA-4 and IL-4 polymorphisms in viral induced liver cancer
    Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Janeen H. Trembley, Areeb Rizwan, Fatima Faraz, Syeda Alveena Shah, Mahrukh Farooqi, Naeem Mahmood Ashraf, Tayyaba Afsar et al. · 2022 · BMC Cancer
  47. Changes in Tumor Immune Microenvironment after Radiotherapy Resistance in Colorectal Cancer: A Narrative Review
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  48. Constitutive Turbodomains enhance expansion and antitumor activity of allogeneic BCMA CAR T cells in preclinical models
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  49. IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p
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  50. Revolutionizing type 1 diabetes management: Exploring oral insulin and adjunctive treatments
    Mohsen Nabi‐Afjadi, Samane Ostadhadi, Mahsa Liaghat, Ajay Prakash Pasupulla, Sajjad Masoumi, Fatemeh Aziziyan, Hamidreza Zalpoor, Leila Abkhooie, Vahideh Tarhriz · 2024 · Biomedicine & Pharmacotherapy
  51. Tracking inflammation status for improving patient prognosis: A review of current methods, unmet clinical needs and opportunities
    Vidya Raju, Revanth Reddy, Arzhang Cyrus Javan, Behnam Hajihossainlou, Ralph Weissleder, Anthony Guiseppi‐Elie, Katsuo Kurabayashi, Simon A. Jones, Rose T. Faghih · 2025 · Biotechnology Advances
  52. Development of IL-15/IL-15Rα sushi domain-IgG4 Fc complexes in Pichia pastoris with potent activities and prolonged half-lives
    Huan Xu, Mingyang Shi, Changsheng Shao, Hao Li, Jing Wu, Yin Yu, Fang Fang, Yugang Guo, Weihua Xiao · 2021 · Microbial Cell Factories
  53. Cuproptosis-related lncRNAs predict the clinical outcome and immune characteristics of hepatocellular carcinoma
    Hongfei Zhu, Feifei Mao, Kang Wang, Jinkai Feng, Shuqun Cheng · 2022 · Frontiers in Genetics
  54. Pseudoprogression manifesting as recurrent ascites with anti-PD-1 immunotherapy in urothelial bladder cancer
    Randy F. Sweis, Yuanyuan Zha, Lomax F. Pass, Brian L. Heiss, Tara Chongsuwat, Jason J. Luke, Thomas Frank Gajewski, Russell Zelig Szmulewitz · 2018 · Journal for ImmunoTherapy of Cancer
  55. Combination Vaccination With Tetanus Toxoid and Enhanced Tumor-Cell Based Vaccine Against Cervical Cancer in a Mouse Model
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  56. Advances in mRNA‐Lipid Nanoparticle Engineering for Immune Cell Targeting and Immune Modulation
    Cheesue Kim, Yeji Lee, Hyukjin Lee, Byung‐Soo Kim · 2025 · Small Methods
  57. Breast neoplasm epithelial-mesenchymal transition and cytokines: a systematic review
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  58. Combinatorial Strategies With PD-1/PD-L1 Immune Checkpoint Blockade for Breast Cancer Therapy: Mechanisms and Clinical Outcomes
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  59. SON-1210 - a novel bifunctional IL-12 / IL-15 fusion protein that improves cytokine half-life, targets tumors, and enhances therapeutic efficacy
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  60. Durable antitumor response via an oncolytic virus encoding decoy-resistant IL-18
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  61. Emerging Frontiers in Colorectal Cancer Therapy: From Targeted Molecules to Immunomodulatory Breakthroughs and Cell-Based Approaches
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  62. Is AAV-delivered IL-27 a potential immunotherapeutic for cancer?
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  63. Impact of noncoding RNAs on cancer directed immune therapies: Now then and forever
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  64. Saga of monokines in shaping tumour-immune microenvironment: Origin to execution
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  65. Prognostic significance and mechanisms of CXCL genes in clear cell renal cell carcinoma
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  66. Beyond CAR T cells: Engineered Vγ9Vδ2 T cells to fight solid tumors
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  67. The Bioinformatics-Based Analysis Identifies 7 Immune-Related Genes as Prognostic Biomarkers for Colon Cancer
    Jie Pan, Zongqi Weng, Chaorong Xue, Bing-qiang Lin, Mengxin Lin · 2021 · Frontiers in Oncology
  68. Reversing vemurafenib‐resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects
    Alessandra Fragale, Emilia Stellacci, Giulia Romagnoli, Valerio Licursi, Stefania Parlato, Irene Canini, Giacomo Remedi, Maria Buoncervello, Paola Matarrese, Lucia Pedace et al. · 2023 · International Journal of Cancer
  69. Interleukins and interferons in mesenchymal stromal stem cell-based gene therapy of cancer
    Urban Švajger, Urška Kamenšek · 2024 · Cytokine & Growth Factor Reviews
  70. Nanomedicine-based cancer immunotherapy: a bibliometric analysis of research progress and prospects
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  71. Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients
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  72. Recent advances in AIE-based platforms for cancer immunotherapy
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  73. Natural Killer Cell‐Mediated Antitumor Immunity: Molecular Mechanisms and Clinical Applications
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  74. Research advances of secretory proteins in malignant tumors
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  75. Immunotherapy: A new target for cancer cure (Review)
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  76. IL12/18/21 Preactivation Enhances the Antitumor Efficacy of Expanded γδT Cells and Overcomes Resistance to Anti–PD-L1 Treatment
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  77. Advances in engineering and delivery strategies for cytokine immunotherapy
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  78. The role of intestinal flora on tumor immunotherapy: recent progress and treatment implications
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  79. Emerging IL-12-based nanomedicine for cancer therapy
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  80. Controlling tumor progression and recurrence in mice through combined treatment with a PD-L1 inhibitor and a designer Salmonella strain that delivers GM-CSF
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  81. Natural killer cell memory: challenges and opportunities for cancer immunotherapy
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  82. Siglec-15 antibody–GM-CSF chimera suppresses tumor progression via reprogramming tumor-associated macrophages
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  83. Advances and challenges in cancer immunotherapy: Strategies for personalized treatment
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  84. Advancing Cancer Immunotherapy Using Lipid Nanoparticle-Based Approaches
    Pedro Henrique Dias Moura Prazeres, Gabriel Costa da Silva, Giovane Azevedo, Natália Jordana Alves da Silva, Pedro Augusto Carvalho Costa, Walison da Silva, Anderson Oliveira Lobo, Pedro Pires Goulart Guimarães · 2025 · International Journal of Nanomedicine
  85. Cytokines and Chemokines in Cancer Cachexia and Its Long-Term Impact on COVID-19
    Santosh Kumar Singh, Rajesh Singh · 2022 · Cells
  86. Drug Repurposing by Tumor Tissue Editing
    Florian Lüke, Dennis Christoph Harrer, Pan Pantziarka, Tobias Pukrop, Lina Ghibelli, Christopher Gerner, Albrecht Reichle, Daniel Heudobler · 2022 · Frontiers in Oncology
  87. Revitalizing Cytokine‐Based Cancer Immunotherapy through Advanced Delivery Systems
    Pengwen Chen, West Kristian D. Paraiso, Horacio Cabral · 2023 · Macromolecular Bioscience
  88. Overview of Basic Immunology and Clinical Application
    Bettzy Stephen, Joud Hajjar · 2020 · Advances in experimental medicine and biology
  89. Novel classes of immunotherapy for breast cancer
    Alberto Hernando‐Calvo, David W. Cescon, Philippe Lucien Bedard · 2021 · Breast Cancer Research and Treatment
  90. Prognostic role of serum cytokines level in non-small cell lung cancer patients with anti-PD-1 and chemotherapy combined treatment
    Hongyu Liu, Chao Zhou, Haohua Jiang, Tianqing Chu, Runbo Zhong, Xueyan Zhang, Yinchen Shen, Baohui Han · 2024 · Frontiers in Immunology
  91. Advances in Liposomal Interleukin and Liposomal Interleukin Gene Therapy for Cancer: A Comprehensive Review of Preclinical Studies
    Eman A. Kubbara, Ahmed Kamal Bolad, Husam M. Malibary · 2025 · Pharmaceutics
  92. Overcoming cancer immunotherapy barriers via nanomaterial-mediated pyroptosis
    Jianlei Xie, Baoxin Peng, Yu Xiao, Xiasang Chen, Xinying Zhang, Diqi Chen, Lijuan Song, Meiqian Xu, Wenjing Liao, Xiaowen Zhang · 2025 · Journal of Materials Chemistry B
  93. The “double-edged sword” effect of cytokines in cancer: coexisting opportunities and challenges
    Xuan Yin, Wangzheqi Zhang, Guanhua Wang, Yawei Liu, Bing Dai, Liping Yue · 2025 · Frontiers in Immunology
  94. Bioengineering strategies to enhance the interleukin-18 bioactivity in the modern toolbox of cancer immunotherapy
    Mojtaba Taheri, Hossein Abdul Tehrani, Fatemeh Daliri, Mona Alibolandi, Masoud Soleimani, Alireza Shoari, Ehsan Arefian, Mohammad Ramezani · 2023 · Cytokine & Growth Factor Reviews
  95. Redirecting oncolytic viruses: Engineering opportunists to take control of the tumour microenvironment
    Taylor R. Jamieson, Joanna Poutou, Carolina S. Ilkow · 2020 · Cytokine & Growth Factor Reviews
  96. Evaluation of the clinical application value of cytokine expression profiles in the differential diagnosis of prostate cancer
    Rongfa Chen, Linna Liu, Hui Chen, Chao Xing, Tingting Zhang, Yilin Pang, Xunjun Yang · 2024 · Cancer Immunology Immunotherapy
  97. Localized Nano-mediated Interleukin-12 Gene Therapy: Promising Candidate for Cancer Immunotherapeutics
    Moganavelli Singh, Jeaneen Venkatas · 2022 · Current Cancer Drug Targets
  98. GT-00AxIL15, a Novel Tumor-Targeted IL-15-Based Immunocytokine for the Treatment of TA-MUC1-Positive Solid Tumors: Preclinical In Vitro and In Vivo Pharmacodynamics and Biodistribution Studies
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  99. Harnessing immunotherapy for hepatocellular carcinoma: Principles and emerging promises
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  100. Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma
    Shawna A. Shirley, Cathryn G. Lundberg, Richard F. Heller · 2020 · Cancers