The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Regulation of Bone Metabolism by Sex Steroids
Open accessAbstract
Osteoporosis is a significant public health problem, and a major cause of the disease is estrogen deficiency following menopause in women. In addition, considerable evidence now shows that estrogen is also a major regulator of bone metabolism in men. Since the original description of the effects of estrogen deficiency on bone by Fuller Albright more than 70 years ago, there has been enormous progress in understanding the mechanisms of estrogen and testosterone action on bone using human and mouse models. Although we understand more about the effects of estrogen on bone as compared with testosterone, both sex steroids do play important roles, perhaps in a somewhat compartment-specific (i.e., cancellous vs. cortical bone) manner. This review summarizes our current knowledge of sex steroid action on bone based on human and mouse studies, identifies both agreements and potential discrepancies between these studies, and suggests directions for future research in this important area.
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The 2022 hormone therapy position statement of The North American Menopause Society
(2022) · Menopause · doi:10.1097/gme.0000000000002028 · Cited by 977
Regulation of Energy Metabolism by Bone-Derived Hormones
Mera, P., Ferron, M., & Mosialou, I. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a031666 · Cited by 90
Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts
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Metadata
- Authors
- Khosla, S., & Monroe, D. G.
- Venue
- Cold Spring Harbor Perspectives in Medicine
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2017-07-14
- Volume
- 8
- Issue
- 1
- Pages
- a031211
- ISSN
- 2157-1422 (ISSN-L)
- OpenAlex
- W2735579573
- Cited by
- 323
- References
- 73
- Type
- posted content
- Language
- en
- Open access
- bronze
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