Using Mendelian Randomization to Improve the Design of Randomized Trials

Cited by (339)

Items 301–339 of 339

1. Exploring the gut microbiota-microbial metabolites-targets regulatory network in metabolic dysfunction-associated steatotic liver disease
   Dapeng Yin, Wei Wu, X. Wang, Junhua He, Yikun Zhu, Jin Li · 2026 · Frontiers in Molecular Biosciences
2. Causal relationship between hydrogen sulfide and osteoarthritis: A Mendelian randomization analysis
   Peng Yang, Yi Jiang, Jun Ma, Xiaofei Ye, Lina Liu, Jiuyi Sun · 2026 · Medicine
3. Causal Risk Factors for Type 1 Diabetes in Mendelian Randomization Studies: A Systematic Review and Meta-Analysis
   Mali Li, Panting Shen, Chao Liu, Jin Li, Shichao Qiu, Zhihua Wang · 2026 · Diabetes Metabolic Syndrome and Obesity
4. Air pollution and female reproductive traits: insights from bibliometrics and Mendelian randomization
   Fan-Hua Cao, Shuo Chen, Linlin Liu, Shuang-Long Cai, Q. Zhou · 2026 · International Journal of Environmental Health Research
5. Assessing the Association Between T2DM, Rheumatoid Arthritis, and Dipeptidyl Peptidase‐4 Inhibitors: Insights From Epidemiology, Meta‐Analysis, and Mendelian Randomization Study
   Lirong Zhang, Lan Lin, Jingting Wang, Yixiao Zhu, Jiaqin Cai, Hong Sun, Xiaoxia Wei · 2026 · Journal of Diabetes Research
6. Causal Association of Circulating Adipokines With the Risk of Carpal Tunnel Syndrome and Diabetic Neuropathy: A Bidirectional Two‐Sample Mendelian Randomization Study
   Hongquan Wen, Zhiqiang Fan, P. Wang, Jia Li · 2026 · Journal of Diabetes Research
7. Class-Specific Antihypertensives and Alzheimer’s Disease: Genotype- and Hypertension-Stratified Analysis
   Dehao Yang, Ruting Wei, Jie Zhu, Jiaxuan Chen, Shiyue Wang, Hejia Cai, Bo Zhang, Bingxin Teng, Bo Li, Xiaoya Xie et al. · 2026 · Molecular Neurobiology
8. Association between genetically predicted dietary patterns and atrial fibrillation: a two sample Mendelian randomization study
   Xinpeng You, Wenxing Guo, Kai Huang, Chenghao Zhong, Ling Yang, Qi Jiang · 2026 · European Journal of Nutrition
9. Genetic Regulation of Monocyte MicroRNAs and Their Implication in Musculoskeletal Diseases: A Cross-Ancestry Expression Quantitative Trait Loci and Imputation Study
   Yong Liu, Kuan-Jui Su, Yun Gong, Bo Tian, Anqi Liu, Zhe Luo, Qing Tian, Chuan Qiu, Hui Shen, He Xiao et al. · 2026 · International Journal of Molecular Sciences
10. Identification of colorectal cancer immune biomarkers via eQTL mapping: a Mendelian randomization and transcriptomic analysis study
    Genyuan Pu, Zi Yin, Xin Zhang, Zhiqi Liu, Caiting Yang, Chunping Xu, Mingming Lai · 2026 · PeerJ
11. Genetically predicted anti‑rubella virus IgG levels and dermatitis risk: A two‑sample Mendelian randomization study
    Zidan Ouyang, Jiajian Lin, Jing Wu, Xiaojun Wang, Haijiao Wang, Li Chen · 2026 · Virus Research
12. Exploring the role of adenosine deaminase in esophageal cancer and its potential for traditional Chinese medicine intervention
    Xiaoling Tian, Yanhong Liu, Baochun Wang, Yubo Liu, Fengqi Liu, Chenlin Wang, Shuang Lv, Yunqi Hua, Fangrui Yin · 2026 · Frontiers in Molecular Biosciences
13. Causal Effects of Female Reproductive and Hormonal Factors on Osteoporosis, Bone Mineral Density, and Osteoarthritis: A Two-Sample Mendelian Randomization Study
    Guangjun Li, Wen Shen, Jian Chen, Yuxiang Dai, Guowei Mo, Songhao Wang, Xin Wang · 2026 · International Journal of Women s Health
14. Exploring mitochondrial genetic features in intervertebral disc degeneration through multi-omics integration analyses
    Fangxing Xu, Chao Wang, Meng Sun, Shuai Shi, Xuyao Wang, Donghui Liu, Lianhao Yu, Chunyang Xi, Pengyu Kong · 2026 · The Journals of Gerontology Series A
15. Multi-omics mendelian randomization integrating GWAS and eQTL data revealed potential drug target for irritable bowel syndrome
    Huiwen Ke, Wenchao Chen, Qian Zhang, Zipeng Liu, Pengfei Wei, Li Li, Haitao Yu, Dongmei Huang, Chaoting Lan, Ning Xu et al. · 2026 · Frontiers in Genetics
16. Relationships between immune cells, blood metabolites, and intrahepatic cholangiocarcinoma: a Mendelian randomization study with experimental validation
    Zhipeng Ye, BuLang Tang, Yuanjian Zhang, Hanhan Chen, Jie Li, Z Ye, Xuejian Liu, Di Li · 2026 · Frontiers in Cell and Developmental Biology
17. Circulating IL-17 a as a downstream inflammatory indicator of depression: Insights from mendelian randomization and animal experiments
    Zhenchen Lu, Qiaoyu Yang, Shansong Hu, Han Wu, Liuliu Lu, Yiwei Shao, Bingqing Ye, L L Li, Zeng Li, Rong Li et al. · 2026 · Cytokine
18. Genetic evidence for potential causal associations between gut microbiota and site-specific urolithiasis risk: a two-sample mendelian randomization study
    Laiyu Yang, Bin Liu, Xinquan Gu · 2026 · Urolithiasis
19. The Use of Genetic Testing in the Management and Treatment of Kidney Stones
    Trisha Laxamana, Niveda Shekar, David S. Goldfarb · 2026 · Advances in Kidney Disease and Health
20. Integrating multi-omics and mendelian randomization identifies therapeutic targets for Lichen Sclerosus: A druggable genome-wide study
    Shuai Wang, Pengfei Wang, Haiping Li, Xinyi Guan, Shuling Ji, Xian Zhang, Yuanhong Chen, Nan Li, Hu Li, Lujiadai Xue et al. · 2026 · Global Medical Genetics
21. A meta-analysis of the long-term effects of antihypertensive therapy on the risk of major cardiovascular disease across 51 randomized trials
    Q Yang, Zeinab Bidel, Dexter Canoy, Guyu Zeng, William C. Cushman, Anthony Rodgers, Koon Teo, B Davis, John Philip Chalmers, Carl J. Pepine et al. · 2026 · Nature Medicine
22. Gut microbiota influences gastric cancer through the mediation of inflammatory proteins: A Mendelian randomization analysis
    Chenyang Yu, Fule Wang, Xinfang Zhang, Wenzhao Guo, Changchuan Bai, Guanhua Lv · 2026 · Medicine
23. Genetic Links Between Cancer and Coronary Atherosclerosis: A Mendelian Randomization Analysis
    Yanan Fan, Miaomiao Liu, L J Zhang, Fei Liu, Jiantao Dong, M Y Zhang, Lixiao Zhang, Yun Sun, Wenjing Yao, Wei Geng · 2026 · Human Mutation
24. Multi-omics Mendelian randomization identified adaptive immune response–related drug targets in psoriatic arthritis
    Zhaopeng Fan, Qi Dong, Le Ding, Lintao Zhang, Xue Yun, Hua Guo · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
25. PNPT1-induced mitochondrial dysfunction drives osteoclast activation via post-transcriptional Nrf2 suppression and lipid peroxidation signaling
    Chengyan Liu, Xinlin Nie, Fangze Xing, Dongbo Wang, Chenkun Liu, Lu Feng, Jiewen Zhang, Yiwei Zhao, Ruomu Cao, Sen Luo et al. · 2026 · International Immunopharmacology
26. The Impact of Omega Fatty Acids on DKD : A Multimodal Study Integrating Mendelian Randomization, Proteomic Mediation Analysis, and Meta‐Analysis
    Li Zhang, Mei‐yan Wu, Tingting Pan, Dong Dan, Shuai Xue · 2026 · The FASEB Journal
27. A study on risk factors for the progression from T2DM to end-stage renal disease based on Mendelian randomization and logistic regression analysis
    Yakun Wang, Xinjia Guo, Yanhong Li, Qiyu Fu, Chong Zhang, Shoujun Bai · 2026 · Renal Failure
28. Causal associations between human metabolites and functional dyspepsia: Evidence from two sample and multivariable Mendelian randomization
    Lijuan Long, Mengyu Li, Liqiong Liu, Lijuan Zhang · 2026 · Medicine
29. Genetic evidence linking circadian rhythm genes and hypertension: A two-sample Mendelian randomization study
    Le Wang, Yue-Qi Leng, Wei-Zhong Wang, Jia‐Cen Sun · 2026 · Journal of International Medical Research
30. Identification of B-cell senescence-related key genes and mechanisms in Alzheimer's disease through transcriptomic sequencing combined with Mendelian randomization analysis and experimental verification
    Rong Yuan, Guihua Liao, Shaohui Su, Jiayan Shan, Shanhong Tang · 2026 · Journal of Alzheimer s Disease
31. Exploration of the mechanism of gut microbiota-mediated immune modulation in the pathogenesis of pancreatic cancer
    Mengwei Cai, Haonan Cheng, Yakang Jia, Tianjian Qiu, Ze-Long Liu, Junyan Xu, Hui Li, Zhihao Zhang, Jin Wang · 2026 · Medicine
32. Mendelian Randomization Investigating the Association between Circulating Immune T Cells and Crohn’s Disease
    翊林 张 · 2026 · Advances in Clinical Medicine
33. Genome-wide association summary statistics-based genetic mapping of brain functional and structural networks in Type 2 diabetes mellitus and its complications
    Lin Chen, Hsinyu Hsieh, Nan Cheng, Yin Xu · 2026 · Brain Research Bulletin
34. Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors
    Binyue Xu, Xuhuan Li, Shangling Dong, Zheyuan Zhang, Dong Jin, Guoping Li, Jiesheng Wang · 2026 · CNS Neuroscience & Therapeutics
35. Exploration of Key Targets and Potential Mechanisms of Traditional Chinese Medicine Intervention in Bipolar Disorder Based on Bioinformatics, Machine Learning, and Mendelian Randomization
    Ze-Feng Zhang, Kai-Rui Zhang, Zhu-Jiang Li, Pei-Pei Qiao, Ming-Yu Yu, Pan-Pan Huang · 2026 · Proceedings of the 2026 2nd International Conference on Health Big Data
36. Identification and expression validation of key genes of Xiaozhengtongluo formula in the treatment of diabetic nephropathy by Mendelian randomization
    Zhao Liu, Moxixuan Liu, Haina Wu, Ying Zhang, Zhiqiang Chen, Xiaona Wei, Yun Ma, Xinai Wang, Hui Gao, Jinmei Zheng et al. · 2026 · Functional & Integrative Genomics
37. Causal interplay between major depressive disorder and cognitive impairment: A bidirectional Mendelian randomization study with brain imaging mediation
    Yilin Tang, Qingli Mu, Sirui Gao, Wanting Feng, Bangshan Liu, Yumeng Ju, Mi Wang, Kai Gao, Yan Zhang, Mei Liao et al. · 2026 · Journal of Affective Disorders
38. Lung cancer and altered brain structure
    Zhen Yuan, Zhiwei Xu, Shuyue Lv, Yin Dong, Aoli Chen, Wenchao Wang, Jiwei Cheng · 2026 · Medicine
39. Bidirectional causal associations between Sjögren syndrome and gastrointestinal disorders
    Qiaofeng Wei, Lanlan Li, Qing Du, Hongju Zhang · 2026 · Medicine