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Cited by 225

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae.

Open access
Nikawa, J, Cameron, S, Toda, T, Ferguson, K M, Wigler, M·1987·Genes & Development

Abstract

We have isolated and characterized normal and mutant alleles of many of the genes of the RAS/adenylyl cyclase pathway of the yeast Saccharomyces cerevisiae. Manipulation of those genes has revealed a system for feedback control that can modulate cAMP levels over at least a 10,000-fold range. The feedback control depends upon the activity of the cAMP-dependent protein kinases and requires the presence of the CDC25 and RAS proteins. The capacity for such dramatic control of cAMP levels raises fundamental questions about the normal mechanism of action of the cAMP signaling system in yeast.

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Metadata

Authors
Nikawa, J., Cameron, S., Toda, T., Ferguson, K. M., & Wigler, M.
Venue
Genes & Development
Published
1987-11
Volume
1
Issue
9
Pages
931-937
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2132444456
Cited by
225
References
1
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. https://app.cochat.ai/papers/10.1101/gad.1.9.931
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Nikawa, J., Cameron, S., Toda, T., Ferguson, K. M., & Wigler, M. (1987). Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Genes & Development. https://doi.org/10.1101/gad.1.9.931

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.