The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis
Open accessAbstract
Members of the mammalian mismatch repair protein family of MutS and MutL homologs have been implicated in postreplicative mismatch correction and chromosome interactions during meiotic recombination. Here we demonstrate that mice carrying a disruption in MutS homolog Msh5 show a meiotic defect, leading to male and female sterility. Histological and cytological examination of prophase I stages in both sexes revealed an extended zygotene stage, characterized by impaired and aberrant chromosome synapsis, that was followed by apoptotic cell death. Thus, murine Msh5 promotes synapsis of homologous chromosomes in meiotic prophase I.
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Cites
PCR protocols — A guide to methods and applications
U.G. (1990) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(90)90252-7 · Cited by 11,702
Histological and Histopathological Evaluation of the Testis
Russell, L. D., Ettlin, R. A., Hikim, A. P. S., & Clegg, E. D. (1993) · International Journal of Andrology · doi:10.1111/j.1365-2605.1993.tb01156.x · Cited by 2,246
MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR
Modrich, P. (1991) · Annual Review of Genetics · doi:10.1146/annurev.ge.25.120191.001305 · Cited by 892
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
Baker, S. M., Plug, A. W., Prolla, T. A., Bronner, C. E., Harris, A. C., Yao, X., Christie, D.-M., Monell, C., Arnheim, N., Bradley, A., et al. (1996) · Nature Genetics · doi:10.1038/ng0796-336 · Cited by 829
Xu, Y., Ashley, T., Brainerd, E. E., Bronson, R. T., Meyn, M. S., & Baltimore, D. (1996) · Genes & Development · doi:10.1101/gad.10.19.2411 · Cited by 827
de Wind, N., Dekker, M., Berns, A., Radman, M., & te Riele, H. (1995) · Cell · doi:10.1016/0092-8674(95)90319-4 · Cited by 780
Self-citationPeters, A. H. F. M., Plug, A. W., van Vugt, M. J., & de Boer, P. (1997) · Chromosome Research · doi:10.1023/a:1018445520117 · Cited by 728
Self-citationPittman, D. L., Cobb, J., Schimenti, K. J., Wilson, L. A., Cooper, D. M., Brignull, E., Handel, M. A., & Schimenti, J. C. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80069-6 · Cited by 634
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
Drummond, J. T., Li, G.-M., Longley, M. J., & Modrich, P. (1995) · Science · doi:10.1126/science.7604264 · Cited by 601
Biochemistry and genetics of eukaryotic mismatch repair.
Kolodner, R. (1996) · Genes & Development · doi:10.1101/gad.10.12.1433 · Cited by 592
Cited by
Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability
Peters, A. H. F. M., O'Carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00542-6 · Cited by 1,766
Meiotic Chromosomes: Integrating Structure and Function
Zickler, D., & Kleckner, N. (1999) · Annual Review of Genetics · doi:10.1146/annurev.genet.33.1.603 · Cited by 1,255
Buermeyer, A. B., Deschênes, S. M., Baker, S. M., & Liskay, R. M. (1999) · Annual Review of Genetics · doi:10.1146/annurev.genet.33.1.533 · Cited by 451
Metadata
- Authors
- de Vries, S. S., Baart, E. B., Dekker, M., Siezen, A., de Rooij, D. G., de Boer, P., & te Riele, H.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1999-03-01
- Volume
- 13
- Issue
- 5
- Pages
- 523-531
- ISSN
- 0890-9369 (ISSN-L)
- OpenAlex
- W2166523005
- Cited by
- 365
- References
- 36
- Type
- posted content
- Language
- en
- Open access
- diamond
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- de Vries, S. S., Baart, E. B., Dekker, M., Siezen, A., de Rooij, D. G., de Boer, P., & te Riele, H. (1999). Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis. Genes & Development. https://doi.org/10.1101/gad.13.5.523
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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