The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae
Open accessAbstract
The synaptonemal complex (SC) is a proteinaceous complex that apparently mediates synapsis between homologous chromosomes during meiotic prophase. In Saccharomyces cerevisiae , the Zip1 protein is the integral component of the SC. In the absence of a DNA double-strand break or the SC initiation protein Zip3, Zip1 proteins aggregate to form a polycomplex (PC). In addition, Zip1 is also responsible for DSB-independent nonhomologous centromere coupling at early meiotic prophase. We report here that Zip3 is a SUMO (small ubiquitin-related modifier) E3 ligase and that Zip1 is a binding protein for SUMO-conjugated products. Our results also suggest that at early meiotic prophase, Zip1 interacts with Zip3-independent Smt3 conjugates (e.g., Top2) to promote nonhomologous centromere coupling. At and after mid-prophase, the Zip1 protein begins to associate with Zip3-dependent Smt3 conjugates (e.g., Red1) along meiotic chromosomes in the wild-type cell to form SCs and with Smt3 polymeric chains in the zip3 mutant to form PCs.
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SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?
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THE GENETICS AND MOLECULAR BIOLOGY OF THE SYNAPTONEMAL COMPLEX
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Cited by
Recombination, Pairing, and Synapsis of Homologs during Meiosis
Zickler, D., & Kleckner, N. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016626 · Cited by 799
New Mechanistic and Functional Insights into DNA Topoisomerases
Chen, S. H., Chan, N.-L., & Hsieh, T.-S. (2013) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-061809-100002 · Cited by 369
Ubiquitin-dependent Proteolytic Control of SUMO Conjugates
Uzunova, K., Göttsche, K., Miteva, M., Weisshaar, S. R., Glanemann, C., Schnellhardt, M., Niessen, M., Scheel, H., Hofmann, K., Johnson, E. S., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706505200 · Cited by 314
SUMO-specific proteases: a twist in the tail
Hay, R. T. (2007) · Trends in Cell Biology · doi:10.1016/j.tcb.2007.08.002 · Cited by 273
Metadata
- Authors
- Cheng, C.-H., Lo, Y.-H., Liang, S.-S., Ti, S.-C., Lin, F.-M., Yeh, C.-H., Huang, H.-Y., & Wang, T.-F.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2006-07-17
- Volume
- 20
- Issue
- 15
- Pages
- 2067-2081
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2151137171
- Cited by
- 264
- References
- 49
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Cheng, C.-H., Lo, Y.-H., Liang, S.-S., Ti, S.-C., Lin, F.-M., Yeh, C.-H., Huang, H.-Y., & Wang, T.-F. (2006). SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes & Development. https://doi.org/10.1101/gad.1430406
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