The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Direct interaction of ligand–receptor pairs specifying stomatal patterning
Open accessAbstract
Valves on the plant epidermis called stomata develop according to positional cues, which likely involve putative ligands (EPIDERMAL PATTERNING FACTORS [EPFs]) and putative receptors (ERECTA family receptor kinases and TOO MANY MOUTHS [TMM]) in Arabidopsis . Here we report the direct, robust, and saturable binding of bioactive EPF peptides to the ERECTA family. In contrast, TMM exhibits negligible binding to EPF1 but binding to EPF2. The ERECTA family forms receptor homomers in vivo. On the other hand, TMM associates with the ERECTA family but not with itself. While ERECTA family receptor kinases exhibit complex redundancy, blocking ERECTA and ERECTA-LIKE1 (ERL1) signaling confers specific insensitivity to EPF2 and EPF1, respectively. Our results place the ERECTA family as the primary receptors for EPFs with TMM as a signal modulator and establish EPF2–ERECTA and EPF1–ERL1 as ligand–receptor pairs specifying two steps of stomatal development: initiation and spacing divisions.
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1 retracted
Voinnet, O., Rivas, S., Mestre, P., & Baulcombe, D. (2003) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01676.x · Cited by 1,734
RetractedFloral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Clark, S. E., Williams, R. W., & Meyerowitz, E. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80239-1 · Cited by 1,373
Pattern-recognition receptors in plant innate immunity
Zipfel, C. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2007.11.003 · Cited by 658
Jeong, S., Trotochaud, A. E., & Clark, S. E. (1999) · The Plant Cell · doi:10.1105/tpc.11.10.1925 · Cited by 633
Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells
Okuda, S., Tsutsui, H., Shiina, K., Sprunck, S., Takeuchi, H., Yui, R., Kasahara, R. D., Hamamura, Y., Mizukami, A., Susaki, D., et al. (2009) · Nature · doi:10.1038/nature07882 · Cited by 615
Self-citationStomatal Patterning and Differentiation by Synergistic Interactions of Receptor Kinases
Shpak, E. D., McAbee, J. M., Pillitteri, L. J., & Torii, K. U. (2005) · Science · doi:10.1126/science.1109710 · Cited by 586
Self-citationThe secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule
Hara, K., Kajita, R., Torii, K. U., Bergmann, D. C., & Kakimoto, T. (2007) · Genes & Development · doi:10.1101/gad.1550707 · Cited by 546
Self-citationControl of Stomatal Distribution on the Arabidopsis Leaf Surface
Nadeau, J. A., & Sack, F. D. (2002) · Science · doi:10.1126/science.1069596 · Cited by 524
Arabidopsis CLV3 Peptide Directly Binds CLV1 Ectodomain
Ogawa, M., Shinohara, H., Sakagami, Y., & Matsubayashi, Y. (2008) · Science · doi:10.1126/science.1150083 · Cited by 512
Cited by
Mechanisms of Stomatal Development
Pillitteri, L. J., & Torii, K. U. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105451 · Cited by 389
Self-citationOsakabe, Y., Yamaguchi-Shinozaki, K., Shinozaki, K., & Tran, L.-S. P. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ers354 · Cited by 384
Disease Resistance Gene Analogs (RGAs) in Plants
Sekhwal, M., Li, P., Lam, I., Wang, X., Cloutier, S., & You, F. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160819248 · Cited by 327
Guo, T., Chen, K., Dong, N.-Q., Shi, C.-L., Ye, W.-W., Gao, J.-P., Shan, J.-X., & Lin, H.-X. (2018) · The Plant Cell · doi:10.1105/tpc.17.00959 · Cited by 316
SERKing Coreceptors for Receptors
Ma, X., Xu, G., He, P., & Shan, L. (2016) · Trends in Plant Science · doi:10.1016/j.tplants.2016.08.014 · Cited by 266
Metadata
- Authors
- Lee, J. S., Kuroha, T., Hnilova, M., Khatayevich, D., Kanaoka, M. M., McAbee, J. M., Sarikaya, M., Tamerler, C., & Torii, K. U.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2012-01-12
- Volume
- 26
- Issue
- 2
- Pages
- 126-136
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2112576661
- Cited by
- 342
- References
- 27
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Lee, J. S., Kuroha, T., Hnilova, M., Khatayevich, D., Kanaoka, M. M., McAbee, J. M., Sarikaya, M., Tamerler, C., & Torii, K. U. (2012). Direct interaction of ligand–receptor pairs specifying stomatal patterning. Genes & Development. https://doi.org/10.1101/gad.179895.111
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