Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

Cited by (306)

Items 201–300 of 306

1. Promoter methylation blocks FES protein‐tyrosine kinase gene expression in colorectal cancer
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2. DNA methylation and specific protein—DNA interactions
   Peter L. Molloy, Fujiko Watt · 1990 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
3. MINIREVIEW: A Role for DNA Methylation in Vertebrate Gene Expression?
   Jeannine S. Strobl · 1990 · Molecular Endocrinology
4. Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium
   Romina Beatriz Cejas, Daniel C. J. Ferguson, Adolfo Quiñones‐Lombraña, Jonathan Bard, Javier G. Blanco · 2019 · Scientific Reports
5. Widespread effects of DNA methylation and intra-motif dependencies revealed by novel transcription factor binding models
   Jan Grau, Florian Schmidt, Marcel H. Schulz · 2023 · Nucleic Acids Research
6. The TGF-β profibrotic cascade targets ecto-5′-nucleotidase gene in proximal tubule epithelial cells and is a traceable marker of progressive diabetic kidney disease
   Claudio Cappelli, Analia Tellez, Claudia Jara, Sebastián Alarcón, Ángelo Torres, Pablo Mendoza, Loreto Podestá, Claudio Flores, Claudia Quezada, Carlos E. Oyarzun et al. · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
7. Methylation-associated Transcriptional Silencing of the Major Histocompatibility Complex-linked hsp70 Genes in Mouse Cell Lines
   Jacek J. Gorzowski, Carrie A. Eckerley, Robert G. Halgren, Allison B. Mangurten, Benette Phillips · 1995 · Journal of Biological Chemistry
8. The CpG‐rich promoter of human LDH‐C is differentially methylated in expressing and nonexpressing tissues
   Christophe Bonny, Erwin Goldberg · 1995 · Developmental Genetics
9. The US‐1 element from the gene encoding rat poly (ADP‐ribose) polymerase binds the transcription factor Sp1
   Frédeéric POTVIN, René J. ROY, Guy G. Poirier, Sylvain L. Guérin · 1993 · European Journal of Biochemistry
10. CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription
    Tae Gi Uhm, Seol Kyung Lee, Byung Soo Kim, Jin Hyun Kang, Choon-Sik Park, T. Rhim, Hun-Soo Chang, DoJin Kim, I. Chung · 2012 · Experimental and Molecular Medicine
11. Extinction of Oct-3/4 Gene Expression in Embryonal Carcinoma × Fibroblast Somatic Cell Hybrids is Accompanied by Changes in the Methylation Status, Chromatin Structure, and Transcriptional Activity of the Oct-3/4 Upstream Region
    E Ben-Shushan, Eli Pikarsky, Avihu Klar, Yehudit Bergman · 1993 · Molecular and Cellular Biology
12. A nuclear protein with enhanced binding to methylated Sp1 sites in the AIDS virus promoter
    Peteranne B. Joel, Wei Shao, Karen R. Pratt · 1993 · Nucleic Acids Research
13. Functional analysis of the promoters of the human CaMIII calmodulin gene and of the intronless gene coding for a calmodulin-like protein
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14. Increased binding of SP1 to the γ‐globin gene promoter upon site‐specific cytosine methylation
    Pritam K. Sengupta, Donald Lavelle, Joseph DeSimone · 1994 · American Journal of Hematology
15. Transcriptional repression of the RET proto-oncogene by a mitogen activated protein kinase-dependent signalling pathway
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16. DNA methylation levels and expression patterns of Smyd1a and Smyd1b genes during Metamorphosis of the Japanese Flounder (Paralichthys olivaceus)
    Shuxian Wu, Yajuan Huang, Siping Li, Haishen Wen, Meizhao Zhang, Jifang Li, Yun Li, Changwei Shao, Feng He · 2018 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
17. Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53
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18. Hypomethylation of the Xmrk Oncogene Promoter in Melanoma Cells of Xiphophorus
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19. The Binding of Nuclear Factors to the as‐1 Element in the CaMV 35S Promoter is Affected by Cytosine Methylation in Vitro
    Akira Kanazawa, Michael R. O’Dell, Roger P. Hellens · 2007 · Plant Biology
20. A nuclear protein that binds preferentially to methylated DNA in vitro may play a role in the inaccessibility of methylated CpGs in mammalian nuclei
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21. The Functional Domains of the Murine Thy-1 Gene Promoter
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22. Interplay of ERα binding and DNA methylation in the intron-2 determines the expression and estrogen regulation of cystatin A in breast cancer cells
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23. Cancer Stem Cells: Dynamic Entities in an Ever-Evolving Paradigm
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24. The genetic script of metastasis
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25. FMR1 silencing and the signals to chromatin: a unified model of transcriptional regulation
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26. Inhibition in vitro transcription by specific double-stranded oligodeoxyribonucleotides
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27. Epigenetic Regulation of Dopamine Transporter mRNA Expression in Human Neuroblastoma Cells
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28. The Bulk Chromatin Structure of a Murine Transgene Does Not Vary with Its Transcriptional or DNA Methylation Status
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29. Transcription Factors Nuclear Factor I and Spl Interact with the Murine Collagen α1(I) Promoter
    Michael C. Nehls, Richard A. Rippe, Linda Veloz, David A. Brenner · 1991 · Molecular and Cellular Biology
30. Engineered zinc finger proteins that respond to DNA modification by Hae III and Hha I methyltransferase enzymes 1 1Edited by T. Richmond
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31. Genetic investigation of ocular developmental genes in 52 patients with anophthalmia/microphthalmia
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32. Rapid impact of ?-amyloid on Paxillin in a neural cell line
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33. Presence of a consensus DNA motif at nearby DNA sequence of the mutation susceptible CG nucleotides
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34. Methylation and expression of neurofilament genes in tissues and in cell lines of the mouse
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35. Chromosomal organization and localization of the human histone deacetylase 9 gene (HDAC9)
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36. Sp1 is essential and its position is important for p120 gene transcription: a 35 bp juxtaposed positive regulatory element enhances transcription 2.5 fold
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37. Methylation status of CpG sites and methyl-CpG binding proteins are involved in the promoter regulation of the mouse Xist gene.
    Nathalie Allaman-Pillet, A. DJEMAÏ, Christophe Bonny, Daniel F. Schorderet · 1998 · Europe PMC (PubMed Central)
38. Hemidemethylation is sufficient for chromatin relaxation and transcriptional activation of methylatedaprt gene in mouse P19 embryonal carcinoma cell line
    Gregory E. Cooper, Peggy L. Bishop, Mitchell S. Turker · 1993 · Somatic Cell and Molecular Genetics
39. Putative contributions of the sex chromosome proteins SOX3 and SRY to neurodevelopmental disorders
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40. Eukaryotic DNA methylases and their use for in vitro methylation
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41. Mutant p53s and chromosome 19 microRNA cluster overexpression regulate cancer testis antigen expression and cellular transformation in hepatocellular carcinoma
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42. Regulators Associated with Clinical Outcomes Revealed by DNA Methylation Data in Breast Cancer
    Matthew H. Ung, Frederick S. Varn, Shaoke Lou, Chao Cheng · 2015 · PLoS Computational Biology
43. Effect of Regulatory Element DNA Methylation on Tissue-Type Plasminogen Activator Gene Expression
    Sylvie Dunoyer-Geindre, Anne-Sophie Rivier-Cordey, Carlos Eduardo R. Caetano, Richard J. Fish, Egbert K. O. Kruithof · 2016 · PLoS ONE
44. Methylation-Enhanced Binding of Sp1 to the Stage Selector Element of the Human γ-Globin Gene Promoter May Regulate Development Specificity of Expression
    Stephen M. Jane, Deborah L. Gumucio, Paul A. Ney, John M. Cunningham, Arthur W. Nienhuis · 1993 · Molecular and Cellular Biology
45. Sequence-specific and Methylation-dependent and -independent Binding of Rice Nuclear Proteins to a Rice Tungro Bacilliform Virus Vascular Bundle Expression Element
    He, Xiaoyuan, Fütterer, Johannes, Hohn, Thomas · 2001 · Journal of Biological Chemistry
46. The role of DNA methylation in regulation of the murine Lhx3 gene
    Raleigh Malik, Simon J. Rhodes · 2013 · Gene
47. Correlation between the methylation of the FUT1 promoter region and FUT1 expression in the duodenum of piglets from newborn to weaning
    Chaohui Dai, Li Sun, R.W. Xia, Shouyong Sun, Guoqiang Zhu, Shenglong Wu, Wenbin Bao · 2017 · 3 Biotech
48. DNA Methylation Represses the Murine αl (I) Collagen Promoter by an Indirect Mechanism
    Katherine Rhodes, Richard A. Rippe, Akihiro Umezawa, Michael C. Nehls, David A. Brenner, Michael Breindl · 1994 · Molecular and Cellular Biology
49. [40] Footprinting of DNA-binding proteins in intact cells
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50. Algorithms for CpG Islands Search: New Advantages and Old Problems
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51. Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53−/− cells to trigger G2/M arrest and senescence
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52. Breaking the Silence: The Interplay Between Transcription Factors and DNA Methylation
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53. Epigenetic Mechanisms in the Pathophysiology of Psychotic Disorders
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54. A Tobacco Nuclear Protein that Preferentially Binds to Unmethylated CpG‐rich DNA
    Ursula Fisscher, Peter J. Weisbeek, SJEF C. M. SMEEKENS · 1996 · European Journal of Biochemistry
55. DNA methylation in a sea lamprey vasotocin receptor gene promoter correlates with tissue- and life-stage-specific mRNA expression
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56. Identification of a CpG Island in the Human LRP-2 Gene and Analysis of Its Methylation Status in Parathyroid Adenomas
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57. The Undermethylated State of a CpG Island Region in Igf2 Transgenes Is Dependent on the H19 Enhancers
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58. Characterization and purification of a novel dATP-binding protein in eukaryotes
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59. Seasonal Adaptation: Geographic Photoperiod–Temperature Patterns Explain Genetic Variation in the Common Vole Tsh Receptor
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60. Functional relevance of promoter CpG island of human Angiotensin II type 1 receptor (AT1R) gene
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61. Methylation inhibits the interaction of dna binding proteins with a potential C-ABL intron regulatory element
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62. Widespread effects of DNA methylation and intra-motif dependencies revealed by novel transcription factor binding models
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63. Control of transcription
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64. Transcriptional Regulation, Signaling Pathways, and Subcellular Localization of Corticotropin-Releasing Factor Receptors in the Central Nervous System
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65. The LTR promoter of the rat oncomodulin gene is regulated by cell-line specific accessibility in the LTR U3 region
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66. Promoter cloning and characterization of the rabbit BK channel β1 subunit gene
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67. On the regulation of DNA methylation by higher-order structure in the cell nucleus
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68. The interaction between a leflunomide-response methylation site (cg17330251) and variant (rs705379) on response to leflunomide in patients with rheumatoid arthritis
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69. Human transcription factor genes involved in neuronal development tend to have high GC content and CpG elements in the proximal promoter region
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70. Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine
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71. Triphenyl phosphate induces coordinated DNA methylation and gene expression changes in aquatic embryonic cells
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72. The Role of DNA Methylation in Osteosarcoma Pathogenesis and Therapy
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73. The Association Between Oxidative Stress, Cellular Differentiation And Galectins In Human Promyelocytic Leukemia Cells (HL-60)
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74. H2AX Promoter Demethylation at Specific Sites Plays a Role in STAT5-Induced Tumorigenesis
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75. The Study of Protein-DNA Interactions by Methylation Interference
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79. Binding of the Transcription Factor EBP-80 Mediates the Methylation Response of an Intracistemal A-Particle Long Terminal Repeat Promoter
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80. Sp1
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83. Genetic etiology of hereditary colorectal cancer: new mechanisms and advanced mutation detection techniques
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84. Pharmacodynamic Mechanisms of Tolfenamic Acid Induced SP1 Degradation Relative to Alzheimer's Disease Pathology
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87. Investigating the regulation of c-Fes non-receptor tyrosine kinase activation and gene expression
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88. Functional analysis of the -1087 single nucleotide polymorphism in the IL-10 promoter region.
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89. Herstellung und Charakterisierung von APOBEC-1 transgenen Kaninchen mit dem leberspezifischen APOBEC-1 Promotor der Ratte
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92. Mesenchymal to epithelial reverting transition in breast cancer metastases: A key role for re-expression of E-cadherin
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93. A Predictive Model for Genomic Methylation Targets in Humans Classification of methylation-prone and resistant CpG sites through sequence analysis
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94. ESTABLISHMENT OF A THERAPY FOR XEROSTOMIA INDUCED BY RADIATION THERAPY USING A DNA DEMETHYLATING AGENT
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95. Epigenetic regulation of gene expression in the vascular endothelium
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96. Regulation of CpG island promoters by the histone methyltransferase MLL2
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97. Epigenetic repression of the NFATc1 transcription factor in human lymphomas
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98. Targeting the Transcription of RET Oncogene in Medullary Thyroid Carcinoma Using Drug-Like Small Molecules
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